Life Sciences Commons^™

Healthy Bites: A Challenge-Based Worksite Wellness Nutrition Program, Mary E. Herndon, Adelina J. Espat, Laura R. Nathan-Garner

International Journal of Exercise Science: Conference Proceedings

Purpose: The worksite health promotion literature has shown that successful nutrition communication programs call for making small changes to diet, one at a time. The use of observational learning (role models) and a “challenge” scenario for behavior change is supported by Social Cognitive Theory. The significance of these small changes in worksites is underscored by a recent Harvard Business Review article suggesting workplace wellness programs can return up $2.71 on every $1.00 invested. The purpose of the proposed program, Healthy Bites, is to increase knowledge of employees regarding the impact of specific nutrition behaviors related to reducing cancer risk and …

Altered Irinotecan Pharmacokinetics In Diet-Induced Obesity, Pranav Shah, Adarsh Gandhi, Romi Ghose

International Journal of Exercise Science: Conference Proceedings

Title: Altered Irinotecan Pharmacokinetics in Diet-Induced Obesity

Authors: Pranav Shah*, Adarsh Gandhi and Romi Ghose

Affiliation: University of Houston, Department of Pharmacological and Pharmaceutical Sciences, Houston, TX - 77030

Purpose: Irinotecan (CPT-11) is a topoisomerase I inhibitor that has been shown to be highly effective in treatment of colon, stomach, pancreas, and non-small cell lung cancers. It has recently been shown that CPT-11 administration is associated with liver toxicity and this effect is compounded by baseline obesity. It was found that patients with a BMI index of >25 were twice as much susceptible to developing liver toxicity than patients with …

Relationship Between Dyslipidemia And Physical Activity In Mexican Children, Armando Avila-Rodríguez, Elias H. Avila-Rodriguez, Jesus M. Araujo-Contreras, Efren Rivas-Avila, Rebecca E. Lee, Luis J. Rodriguez-Ortega, Nohe Vargas-Chavez

International Journal of Exercise Science: Conference Proceedings

Purpose: The purpose of this research was to determine the relationship between physical activity and lipid levels in children 10 to 13 years of age living in Durango, Mexico. Method: Cross-sectional study performed in 823 children (n=428, 52% boys; n=395, 48% girls) enrolled in nine elementary schools. Physical activity was monitored in two ways: a) a questionnaire was used to obtain information about physical activity done in the previous week, and b) steps were counted for 24 hours with a Yamax SW-200 pedometer. A subsample of 425 children provided serum samples to determine total-cholesterol (TC), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C) and …

Leptin And Its Association With Obesity Among Mexican Adolescents, Jesus M. Araujo-Contreras, Elias H. Avila-Rodriguez, Armando Avila-Rodriguez, Efren Rivas-Avila, Nelda Mier, Abelardo Camacho-Luis, Nohe Vargas-Chavez

International Journal of Exercise Science: Conference Proceedings

Purpose: To investigate the association between leptin concentrations and nutritional status among a Mexican adolescent population. Methods: Cross-sectional study with 448 adolescents attending five schools in Durango, Mexico. Serum leptin concentrations were measured by ELISA. Other measurements included height, weight, and waist and hip circumference. Body fat of participants was assessed with bio-electrical impedance using a body composition analyzer InBody-720. Sociodemographic information was also collected. Results: Based on IOTF BMI cut-off points, 34.1% of adolescents were overweight and obese and prevalence rates were higher among females (37.1%) than males (29.5%). In agreement with waist circumference, 22.5% of participants …

Angiotensin At2r Activation Increases Ace2/Ang1-7/Masr Axis And Prevents Fatty-Diet-Induced Obesity, Sourashish Nag, Quaisar Ali, Yonnie Wu, Tahir Hussain

International Journal of Exercise Science: Conference Proceedings

Purpose: Adipose tissue, the obligatory site of fat accumulation causing obesity, expresses local renin angiotensin system (RAS). RAS is commonly known to regulate blood pressure. However recently, we observed that angiotensin type 2 receptor (AT2R) activation prevents high-fat diet (HFD)-induced adiposity and hyperinsulinemia. Although, the mechanism(s) is(are) not known. There is evidence that other RAS components namely, the angiotensin type 1 receptor (AT1R) positively regulates while the angiotensin converting enzyme 2 (ACE2), which catalyzes the production of Mas receptor (MasR) peptide agonist Ang (1-7), inversely regulates adiposity and hyperinsulinemia. In light of the RAS inter-regulatory features, we hypothesize that AT2R …

Vitamin D Status In Lean And Obese Mexican American Children, Nadia H. Agha, Whitney L. Breslin, Brian K. Mcfarlin

International Journal of Exercise Science: Conference Proceedings

Vitamin D deficiency is a worldwide problem amongst adolescents and adults, particularly in minority populations due to high skin melanin content. Melanin blocks the absorption of UVB photons, which limits natural vitamin D accumulation, requiring more dietary intake of vitamin D. Vitamin D deficiency is associated with an increased risk for chronic diseases like cardiovascular disease and diabetes mellitus. Low levels of vitamin D are inversely correlated with systemic inflammation possibly mediating the relationship between vitamin D deficiency and disease. Adequate levels of vitamin D may decrease the risks of chronic diseases, including cardiovascular disease, diabetes mellitus, common cancers, and …

Oxidative Low Density Lipoprotein And Exercise: A Historical And Meta-Analysis, Nikita Tailor, Frank Wyatt, Benito Velasquez, Lon Kilgore

International Journal of Exercise Science: Conference Proceedings

PURPOSE: The purpose of this study is to use the meta-analytic approach to determine the impact of exercise on oxidized low density lipoproteins in an adolescent population and the role of oxidized low density lipoprotein in the etiology of atherosclerosis. Oxidized low density lipoprotein (Ox- LDL), a form of low density lipoprotein cholesterol, carries its own risk factors. A lower level of oxidative low density lipoproteins reduces the risk of cardiovascular diseases. METHODS: The evaluation was done using a meta-analytical approach. This approach is useful when similar studies with a small sample size are studied. All the variables are compared …

Elevated Mcp-1, Tnf-Α, Monocyte Concentration, And Dyslipidemia In Obese Mexican-American Children, Whitney L. Breslin, Craig A. Johnston, Kelley Strohacker, Katie C. Carpenter, Tiffany R. Davidson, Jennette P. Moreno, John P. Foreyt, Brian K. Mcfarlin

International Journal of Exercise Science: Conference Proceedings

Background: Obesity is an independent risk factor for chronic disease. The prevalence of obesity is especially high among Mexican-American children. Peripheral blood monocytes contribute to systemic inflammation and may mediate the relationship between obesity and chronic disease. Obesity affects monocytes and the circulating levels of cytokines/chemokines that influence monocyte behavior. Purpose: investigate alterations in blood monocytes and plasma cytokines/chemokine levels among healthy weight (zBMI ≤ 85th percentile; N=66), overweight (zBMI=85^th-95^th percentile; N=23), and obese (zBMI ≥ 95th percentile; N=39) Mexican-American children. Methods: Blood samples were analyzed for total monocyte concentration, pro-inflammatory monocyte concentration, and classic …

Effects Of A Single Bout Of Exercise On Lipoprotein Fractions In Hypercholesterolemic Women, Allen Sexton, Kavya Chelikani, Yunsuk Koh

International Journal of Exercise Science: Conference Proceedings

Effects of a Single Bout of Exercise on Lipoprotein Fractions in Hypercholesterolemic Women

Allen Sexton, Kavya Chelikani, and Yunsuk Koh

Department of Health and Kinesiology, Lamar University, Beaumont, TX 77710

Classification of First Author: Master’s

Background: Abnormal lipoprotein profiles are strongly associated with premature cardiovascular disease. Sedentary lifestyle and menopause may accelerate abnormal lipid and lipoprotein metabolism in women. A single bout of aerobic exercise at moderate intensity may positively alter serum lipoprotein fractions in postmenopausal women with high cholesterol levels.

Objectives: The current study investigated how a single bout of exercise affects lipoprotein fractions in sedentary, postmenopausal women with …

Are Men Cheaper Than Women? Insights From Walking Economy, Nicole S. Schultz, Peter G. Weyand

International Journal of Exercise Science: Conference Proceedings

ARE MEN CHEAPER THAN WOMEN? INSIGHTS FROM WALKING ECONOMY

Nicole S. Schultz and Peter G. Weyand

Southern Methodist University, Locomotor Performance Laboratory, Department of Applied Physiology and Wellness, Dallas, TX 75205

Introduction: The metabolic energy cost of human walking has been extensively studied. However, whether men and women require the same amount of energy (per kg of body mass) to walk at the same speed or cover the same distance remains unresolved. While most predictive algorithms incorporate only body mass and walking speed, we have recently found that mass-specific walking metabolic rates are inversely related to stature. Objective: We tested …

Caffeine And Sprint Performance In Habitual And Caffeine Naive Participants, J. Bradley Jordan, Richard S. Farley, Jennifer L. Caputo

International Journal of Exercise Science

Caffeine is thought to provide ergogenic benefits during endurance performance. However, there is limited research on the effects of caffeine on anaerobic sports performance. The purpose of this study was to examine the effects of 6 mg·kg_-1 of caffeine on repeated sprint performance. The sample included active college students (N = 18), classified as habitual caffeine or caffeine naïve users. Participants completed a 12 x 30-m sprint test with 35 s rest intervals between sprints. Ratings of Perceived Exertion were collected every 3rd sprint. Height and body mass were measured and participants accommodated to the sprint test on …

Effects Of Carbohydrate-Protein Ingestion Post-Resistance Training In Male Rugby Players, Colin J. Coyle Msc, Bernard Donne, Nick J. Mahony

International Journal of Exercise Science

Evidence suggests that carbohydrate-protein (CHO-PRO) drinks post-exercise are an advantageous nutritional recovery intervention. Resistance trained (n = 14, mean ± SD; age 19 ± 1 yr, mass 95 ± 9 kg, % fat 17 ± 4 % and BMI 28.5 ± 1.8 kg.m^-2) male rugby players participated in a study investigating effects of carbohydrate (CHO) and CHO-PRO drinks on subsequent resistance exercise performance. Following an initial resistance training (RT) protocol consisting of 8 circuits of 5 discrete exercises at 10 repetition maximum (RM), participants received 10 mL.kg^-1 BM of randomised sports drink (LCHO, HCHO and CHO-PRO) on …

The Effects Of Muscle Mass On Homocyst(E)Ine Levels In Plasma And Urine, M. René Malinow, Craig L. Lister, Carl De Crée

International Journal of Exercise Science

The present study was designed to examine the relationship between homocyst(e)ine (H[e]) lev-els and muscle mass. Two experimental groups each of 24 Caucasian males, one consisting of higher-muscle mass subjects (HMM) and the other of lower-muscle mass subjects (LMM) par-ticipated in this study. Muscle mass was estimated from 24-hour urine collections of creatinine (Crt). Muscle mass was 40.3 ± 15.9 kg in HMM and 37.2 ± 11.4 kg in LMM (P= 0.002). Mean plasma H(e) levels in HMM were 10.29 ± 2.9 nmol/mL, and in LMM were 10.02 ± 2.4 nmol/L (Not significant, [NS]). Urinary H(e) levels (UH[e]) were 9.95 …