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Full-Text Articles in Life Sciences
Genetic And Nutritional Studies To Elucidate The Role Of Adipose Tissue In The Pathogenesis Of Metabolic Syndrome, Nishan Sudheera Kalupahana
Genetic And Nutritional Studies To Elucidate The Role Of Adipose Tissue In The Pathogenesis Of Metabolic Syndrome, Nishan Sudheera Kalupahana
Doctoral Dissertations
Obesity is a major health problem in the United States and worldwide. It increases the risk for type-2 diabetes and cardiovascular diseases. A chronic low-grade inflammation occurring in white adipose tissue (WAT) is causally linked to the development of insulin resistance (IR), metabolic syndrome and obesity-associated chronic diseases. The aim of this dissertation research was to elucidate the WAT function in metabolic syndrome using genetic (overexpression of an adipose pro-inflammatory hormone, angiotensinogen) and nutritional manipulations/approaches (caloric restriction and omega-3 fatty acids), with specific emphasis on the role of inflammation.
Previous research indicates that WAT renin-angiotensin system (RAS) is overactivated in …
The Effects Of Bisphenol A On Adipose Tissue Development, Metabolism, And Endocrine Function And The Role It May Play In The Development Of Obesity, Brantley Nelson Wyatt
The Effects Of Bisphenol A On Adipose Tissue Development, Metabolism, And Endocrine Function And The Role It May Play In The Development Of Obesity, Brantley Nelson Wyatt
Masters Theses
While diet and sedentary lifestyle remain important factors in the development of obesity, recent findings have shown the possible involvement of environmental obesogens, chemicals that can disrupt homeostatic energy balance and increase adiposity. Bisphenol A (BPA) is a compound used in the manufacturing of plastics as a hardening agent and is ubiquitous in the environment due to its widespread use. BPA has been shown to be an endocrine disruptor through its ability to mimic estrogen, which is now known to play important roles in adipose tissue growth and metabolism. In fact, a small but compelling number of studies have shown …
Effect Of Alpha-Linolenic Acid On Global Fatty Oxidation In Adipocytes And Skeletal Muscle Cells, Bogdan A. Manole
Effect Of Alpha-Linolenic Acid On Global Fatty Oxidation In Adipocytes And Skeletal Muscle Cells, Bogdan A. Manole
Chancellor’s Honors Program Projects
No abstract provided.