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Full-Text Articles in Life Sciences
Germination And Characterization Of Bacillus Anthracis And Bacillus Cereus, Ann Desdemonia Nde-Neh Fowajuh, Ernesto Abel-Santos
Germination And Characterization Of Bacillus Anthracis And Bacillus Cereus, Ann Desdemonia Nde-Neh Fowajuh, Ernesto Abel-Santos
Undergraduate Research Opportunities Program (UROP)
Bacillus cereus and Bacillus anthracis are micro organisms found in soil. Normally, only their spores are found in soil. We recently showed that, B. anthracis and B. cereus do not germinate in soil. Thus, how does B. cereus and B. anthracis continue their life cycle if they can not replicate in soil? We hypothesize that B. cereus and B. anthracis spores may germinate in the gut of nematodes. Caenorhabditis elegans was used as our model nematode to investigate this possibility. Subsequently, the goal of our research is to determine the effect of C. elegans on the life cycle of B. …
Protection Of Macrophages J774a.1 By Purine Nucleoside Analogues From Bacillus Anthracis Mediated Necrosis, Zadkiel R. Alvarez
Protection Of Macrophages J774a.1 By Purine Nucleoside Analogues From Bacillus Anthracis Mediated Necrosis, Zadkiel R. Alvarez
UNLV Theses, Dissertations, Professional Papers, and Capstones
Eight years after the lamentable anthrax attacks, major scientific effort continues to be done, in order to stop imminent acts of bioterrorism. Innovative ways of therapy against the anthrax disease are being investigated. B. anthracis, the etiological agent of the infection, has a dormant stage in its life cycle known as the endospore. When conditions become favorable spores germinate, transforming into vegetative bacteria. In inhalational anthrax, the most fatal manifestation of the disease, spores enter the organism through the respiratory track, and are phagocytosized by alveolar macrophages of the lungs. Spores are able to sense nutrient availability, activating their germination …