Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Life Sciences
Flexible Filamentous Virus Structures From Fiber Diffraction, Gerald Stubbs, Amy Kendall, Michele Mcdonald, Wen Bian, Timothy Bowles, Sarah Baumgarten, Ian Mccullough, Jian Shi, Phoebe Stewart, Esther Bullitt, David Gore, Said Ghabrial
Flexible Filamentous Virus Structures From Fiber Diffraction, Gerald Stubbs, Amy Kendall, Michele Mcdonald, Wen Bian, Timothy Bowles, Sarah Baumgarten, Ian Mccullough, Jian Shi, Phoebe Stewart, Esther Bullitt, David Gore, Said Ghabrial
Ian McCullough
Fiber diffraction data have been obtained from Narcissus mosaic virus, a potexvirus from the family Flexiviridae, and soybean mosaic virus (SMV), a potyvirus from the family Potyviridae. Analysis of the data in conjunction with cryo-electron microscopy data allowed us to determine the symmetry of the viruses and to make reconstructions of SMV at 19 Å resolution and of another potexvirus, papaya mosaic virus, at 18 Å resolution. These data include the first well-ordered data ever obtained for the potyviruses and the best-ordered data from the potexviruses, and offer the promise of eventual high resolution structure determinations.