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Full-Text Articles in Life Sciences

Towards An Understanding Of Salient Neighborhood Boundaries: Adolescent Reports Of An Easy Walking Distance And Convenient Driving Distance, Natalie Colabianchi, Marsha Dowda, Karin A. Pfeiffer, Dwayne E. Porter, Maria João Ca Almeida, Russell R. Pate Dec 2007

Towards An Understanding Of Salient Neighborhood Boundaries: Adolescent Reports Of An Easy Walking Distance And Convenient Driving Distance, Natalie Colabianchi, Marsha Dowda, Karin A. Pfeiffer, Dwayne E. Porter, Maria João Ca Almeida, Russell R. Pate

Faculty Publications

Numerous studies have examined the association between the surrounding neighborhood environment and physical activity levels in adolescents. Many of these studies use a road network buffer or Euclidean distance buffer around an adolescent's home to represent the appropriate geographic area for study (i.e., neighborhood). However, little empirical research has examined the appropriate buffer size to use when defining this area and there is little consistency across published research as to the buffer size used. In this study, 909 12th grade adolescent girls of diverse racial and geographic backgrounds were asked to report their perceptions of an easy walking distance and …


Development Of New Simple Sequence Repeat Markers For Pearl Millet, O. P. Yadav, S. E. Mitchell, A. Zamora, Theresa M. Fulton, Stephen Kresovich Dec 2007

Development Of New Simple Sequence Repeat Markers For Pearl Millet, O. P. Yadav, S. E. Mitchell, A. Zamora, Theresa M. Fulton, Stephen Kresovich

Faculty Publications

No abstract provided.


Species Invasion Shifts The Importance Of Predator Dependence, Blaine D. Griffen, David G. Delaney Dec 2007

Species Invasion Shifts The Importance Of Predator Dependence, Blaine D. Griffen, David G. Delaney

Faculty Publications

The strength of interference between foraging individuals can influence per capita consumption rates, with important consequences for predator and prey populations and system stability. Here we demonstrate how the replacement of a previously established invader, the predatory crab Carcinus maenas, by the recently invading predatory crab Hemigrapsus sanguineus shifts predation from a species that experiences strong predator interference (strong predator dependence) to one that experiences weak predator interference (weak predator dependence). We demonstrate using field experiments that differences in the strength of predator dependence persist for these species both when they forage on a single focal prey species only (the …


1,3,7,10,14,17,21,28,31,42,52,55-Dodeca­Kis(Trifluoro­Meth­Yl)- 1,3,7,10,14,17,21,28,31,42,52,55-Dodeca­Hydro­(C60-IH)[5,6]Fullerene, Natalia B. Shustova Prof. Dr., O.P. Anderson, O. V. Boltalina, S. H. Strauss, I. E. Kareev Nov 2007

1,3,7,10,14,17,21,28,31,42,52,55-Dodeca­Kis(Trifluoro­Meth­Yl)- 1,3,7,10,14,17,21,28,31,42,52,55-Dodeca­Hydro­(C60-IH)[5,6]Fullerene, Natalia B. Shustova Prof. Dr., O.P. Anderson, O. V. Boltalina, S. H. Strauss, I. E. Kareev

Faculty Publications

The title compound, C72F36, is one of four isomers of C60(CF3)12 for which crystal structures have been obtained. The fullerene mol­ecule has an idealized Ih C60 core with the 12 CF3 groups arranged in an asymmetric fashion on two ribbons of edge-sharing C6(CF3)2 hexa­gons, a parametaparaparaparametapara ribbon and a parametapara ribbon, giving an overall pmp 3 mp,pmp structure. There are no cage Csp 3 …


Are There Rearrangement Hotspots In The Human Genome?, Max A. Alekseyev, Pavel A. Pevzner Nov 2007

Are There Rearrangement Hotspots In The Human Genome?, Max A. Alekseyev, Pavel A. Pevzner

Faculty Publications

In a landmark paper, Nadeau and Taylor [18] formulated the random breakage model (RBM) of chromosome evolution that postulates that there are no rearrangement hotspots in the human genome. In the next two decades, numerous studies with progressively increasing levels of resolution made RBM the de facto theory of chromosome evolution. Despite the fact that RBM had prophetic prediction power, it was recently refuted by Pevzner and Tesler [4], who introduced the fragile breakage model (FBM), postulating that the human genome is a mosaic of solid regions (with low propensity for rearrangements) and fragile regions (rearrangement hotspots). However, the rebuttal …


Extracellular Stimuli Specifically Regulate Localized Levels Of Individual Neuronal Mrnas, Dianna E. Willis, Erna A. Van Niekerk, Yukio Sasaki, Mariano Mesngon, Tanuja T. Merianda, Gervan G. Williams, Marvin Kendall, Deanna S. Smith, Gary J. Bassell, Jeffery L. Twiss Sep 2007

Extracellular Stimuli Specifically Regulate Localized Levels Of Individual Neuronal Mrnas, Dianna E. Willis, Erna A. Van Niekerk, Yukio Sasaki, Mariano Mesngon, Tanuja T. Merianda, Gervan G. Williams, Marvin Kendall, Deanna S. Smith, Gary J. Bassell, Jeffery L. Twiss

Faculty Publications

Subcellular regulation of protein synthesis requires the correct localization of messenger RNAs (mRNAs) within the cell. In this study, we investigate whether the axonal localization of neuronal mRNAs is regulated by extracellular stimuli. By profiling axonal levels of 50 mRNAs detected in regenerating adult sensory axons, we show that neurotrophins can increase and decrease levels of axonal mRNAs. Neurotrophins (nerve growth factor, brainderived neurotrophic factor, and neurotrophin-3) regulate axonal mRNA levels and use distinct downstream signals to localize individual mRNAs. However, myelin-associated glycoprotein and semaphorin 3A regulate axonal levels of different mRNAs and elicit the opposite effect on axonal mRNA …


Phenotypic Plasticity May Facilitate Invasion By Aegilops Triuncialis, Andrew R. Dyer Jan 2007

Phenotypic Plasticity May Facilitate Invasion By Aegilops Triuncialis, Andrew R. Dyer

Faculty Publications

One great obstacle to understanding the invasion of nonnative species into native ecosystems is the lack of information on the population biology of the invading species. In particular, morphological and physiological adaptations and potential for phenotypic plasticity will strongly influence a species’ ability to persist and spread in newly invaded ecosystems. Phenotypic plasticity can buffer populations from selection thereby allowing them to survive the establishment phase of the invasion. The annual grass Aegilops triuncialis (Poaceae, Triticeae) has become highly invasive in California (USA) and provides an opportunity to investigate the importance of phenotypic plasticity to persistence and spread in new …


Whole Genome Duplications And Contracted Breakpoint Graphs, Max A. Alekseyev, Pavel A. Pevzner Jan 2007

Whole Genome Duplications And Contracted Breakpoint Graphs, Max A. Alekseyev, Pavel A. Pevzner

Faculty Publications

The genome halving problem, motivated by the whole genome duplication events in molecular evolution, was solved by El-Mabrouk and Sankoff in the pioneering paper [SIAM J. Comput., 32 (2003), pp. 754–792]. The El-Mabrouk–Sankoff algorithm is rather complex, inspiring a quest for a simpler solution. An alternative approach to the genome halving problem based on the notion of the contracted breakpoint graph was recently proposed in [M. A. Alekseyev and P. A. Pevzner, IEEE/ACM Trans. Comput. Biol. Bioinformatics, 4 (2007), pp. 98–107]. This new technique reveals that while the El-Mabrouk–Sankoff result is correct in most cases, it does not hold in …


Colored De Bruijn Graphs And The Genome Halving Problem, Max A. Alekseyev, Pavel A. Pevzner Jan 2007

Colored De Bruijn Graphs And The Genome Halving Problem, Max A. Alekseyev, Pavel A. Pevzner

Faculty Publications

Breakpoint graph analysis is a key algorithmic technique in studies of genome rearrangements. However, breakpoint graphs are defined only for genomes without duplicated genes, thus limiting their applications in rearrangement analysis. We discuss a connection between the breakpoint graphs and de Bruijn graphs that leads to a generalization of the notion of breakpoint graph for genomes with duplicated genes. We further use the generalized breakpoint graphs to study the Genome Halving Problem (first introduced and solved by Nadia El-Mabrouk and David Sankoff). The El-Mabrouk-Sankoff algorithm is rather complex, and, in this paper, we present an alternative approach that is based …