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Articles 1 - 3 of 3
Full-Text Articles in Life Sciences
The Interaction Between Cytoplasmic Dynein And Dynactin Is Required For Fast Axonal Transport, Clare M. Waterman-Storer, Sher B. Karki, Sergei A. Kunetsov, Joel S. Tabb, Dieter G. Weiss, George M. Langford, Erika L.F. Holzbaur
The Interaction Between Cytoplasmic Dynein And Dynactin Is Required For Fast Axonal Transport, Clare M. Waterman-Storer, Sher B. Karki, Sergei A. Kunetsov, Joel S. Tabb, Dieter G. Weiss, George M. Langford, Erika L.F. Holzbaur
Biology - All Scholarship
Fast axonal transport is characterized by the bidirectional, microtubule-based movement of membranous organelles. Cytoplasmic dynein is necessary but not sufficient for retrograde transport directed from the synapse to the cell body. Dynactin is a heteromultimeric protein complex, enriched in neurons, that binds to both microtubules and cytoplasmic dynein. To determine whether dynactin is required for retrograde axonal transport, we examined the effects of anti-dynactin antibodies on organelle transport in extruded axoplasm. Treatment of axoplasm with antibodies to the p150(Glued) subunit of dynactin resulted in a significant decrease in the velocity of microtubule-based organelle transport, with many organelles bound along microtubules. …
Of Medusae And Men: On The Life And Observations Of Alfred G. Mayor, Lester D. Stephens
Of Medusae And Men: On The Life And Observations Of Alfred G. Mayor, Lester D. Stephens
The Courier
Stephens traces the life of the distinguished marine biologist Alfred G. Mayor, who, between 1896 and 1922, conducted scientific expeditions to the South Pacific Islands. He was fascinated not only by the marine invertebrates he found there, but also by the human inhabitants.