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Full-Text Articles in Life Sciences
Ultraviolet Light Reactivation Of Gamma Ray-Induced Lethal Damage In Vertebrate Cells, Stewart W. Cross, H. Gaston Griggs
Ultraviolet Light Reactivation Of Gamma Ray-Induced Lethal Damage In Vertebrate Cells, Stewart W. Cross, H. Gaston Griggs
Journal of the Arkansas Academy of Science
A comparison was made of the extent of UVR of gamma ray induced lethal damage (mitigation of gamma ray-induced lethal effects by appropriate administration of low UV doses) in fish, amphibian, reptile and mammalian tissue culture cell lines. A significant level of UVR was detected in the non-mammalian lines, but the mammalian cells appeared to have lost this ability. Associated mitotic index data is interpreted as supporting the notion that low UV doses, appropriately administered, may aid repair processes in some cells (indirectly) by hindering the antagonistic metabolic processes which convert gamma ray induced lesions to a non-reversible state.
Effects Of Hyperbaric Hypoxia On Some Enzyme Systems In The Mammalian Liver, Dennis A. Baeyens, M. J. Meier
Effects Of Hyperbaric Hypoxia On Some Enzyme Systems In The Mammalian Liver, Dennis A. Baeyens, M. J. Meier
Journal of the Arkansas Academy of Science
The metabolic effects of hypobaric hypoxic stress on the mammalian liver were studied. The lactate dehydrogenase (LDH) and succinate dehydrogenase (SDH) activity of mouse liver homogenates were measured after exposure to an equivalent altitude of 36,000 feet and compared to controls kept at zero altitude. After six and twelve hour incubation periods, the altitude exposed samples demonstrated a significantly higher LDH activity than controls. SDH activity remained unchanged from controls after six hours but was significantly lower than controls after a 12 hour exposure to altitude. It is concluded that the changes in enzyme activity reflect a metabolic control mechanism …