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Full-Text Articles in Life Sciences

Comparison Of The Humoral Immune Response Following Both Bacterial Challenge And Rnai Of Major Factors On Proliferation Of Bartonella Quintana In The Human Louse, Jake Zina Oct 2022

Comparison Of The Humoral Immune Response Following Both Bacterial Challenge And Rnai Of Major Factors On Proliferation Of Bartonella Quintana In The Human Louse, Jake Zina

Masters Theses

Human body lice, Pediculus humanus humanus, and head lice, Pediculus humanus capitis, have been hematophagous ectoparasites of humans for thousands of years. Despite being ecotypes, only body lice are known to transmit bacterial diseases to humans, and it appears that lower humoral and cellular immune responses allow body lice to possess a higher vector competence. We previously observed that the transcription level of the defensin 1 gene was up-regulated only in head lice following oral challenge of Bartonella quintana, a causative agent of trench fever, and also that body lice excreted more viable B. quintana in their …


Weaving An Interdisciplinary Microbiome Career Using Threads From Different Ecosystems, Sarah Hosler Aug 2022

Weaving An Interdisciplinary Microbiome Career Using Threads From Different Ecosystems, Sarah Hosler

Electronic Theses and Dissertations

Animals have trillions of microorganisms living in or on many body sites, these communities of microorganisms are called microbiomes. Microbiomes are typically host-specific, and a lot of information about the host can be determined from investigating them. Microbiome research has many real-world applications, and this thesis utilizes the One Health perspective, which acknowledges the connection of humans, animals, and environments, and emphasizes the need for collaborative, interdisciplinary research. The first interdisciplinary project is an investigation into the bacteria in wild and cultured Atlantic deep-sea scallop, Placopecten magellanicus larvae. Adults in hatcheries can be induced to spawn, but the last two …


Impact Of A Novel Marine Algae Supplement On Inflammatory And Immune Response After High-Intensity Exercise, Caroline Sara Vincenty Jul 2022

Impact Of A Novel Marine Algae Supplement On Inflammatory And Immune Response After High-Intensity Exercise, Caroline Sara Vincenty

Theses and Dissertations

INTRODUCTION: High-intensity exercise (HIE) can damage the musculotendon complex and impact the immune response, which may result in post-exercise inflammation and reductions in strength and performance. Sufficient rest and recovery will improve muscular resilience against future damaging bouts, however HIE with minimal durations of rest are common in athletic competitions that facilitate persistent inflammation and immune dysregulation. Marine algae-derived fucoidans (MA) have previously shown promise to mitigate pro-inflammatory and immune dysregulation responses, however it has not been investigated in the context of HIE. The purpose of this research is to investigate the safety and efficacy of MA on markers of …


Stress Effects On Hydrogen Peroxide Defense Response Of Physcomitrella Patens And Mnium Cuspidatum, Caden Karl Groves May 2022

Stress Effects On Hydrogen Peroxide Defense Response Of Physcomitrella Patens And Mnium Cuspidatum, Caden Karl Groves

Undergraduate Honors Thesis Collection

This project investigated the importance of stresses and the immune system response of hydrogen peroxide formation within the model system Physcomitrella patens, as well as in Mnium cuspidatum. I examined the role of two hormones, abscisic acid and jasmonic acid, along with the role that drought-like conditions play in the specified defense response of hydrogen peroxide production. I hypothesized that abscisic acid would act as an antagonist and reduce hydrogen peroxide production, jasmonic acid would act as an amplifier to increase hydrogen peroxide production and increasing the sodium concentration of the liquid treatment would also act as an antagonist. These …