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Life Sciences Commons

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Theses/Dissertations

2021

Theses

Acridocarpus orientalis

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Full-Text Articles in Life Sciences

Role Of Autophagy In Acridocarpus Orientalis-Induced Anti-Breast Cancer Activity, Suhib Hisham Ahmed Saeed Altabbal Nov 2021

Role Of Autophagy In Acridocarpus Orientalis-Induced Anti-Breast Cancer Activity, Suhib Hisham Ahmed Saeed Altabbal

Theses

Breast cancer is the most frequently diagnosed cancer in women worldwide. Triple Negative Breast Cancer (TNBC), which lacks the expression of the hormonal Estrogen Receptor (ER) and Progesterone Receptor (PR), and the amplification of Human Epidermal Growth Factor Receptor 2 (HER2), is not responsive to the hormonal therapy. Therefore, chemotherapy and radiotherapy, which cause severe side effects, are the current available choices to treat TNBC. Hence, there is an urgent need to find new therapeutic choices for TNBC. It is estimated that 50% of all drugs in clinical use during the 21st century are natural products and plants derived. …