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Full-Text Articles in Life Sciences
Gut Pathophysiology In Mouse Models Of Social Behavior Deficits, Kyla Scott
Gut Pathophysiology In Mouse Models Of Social Behavior Deficits, Kyla Scott
Undergraduate Honors Theses
Autism spectrum disorders (ASD) encompass neurodevelopment disorders characterized by atypical patterns of development that impact multiple areas of functioning beginning in early childhood. The etiology of ASD is unknown and there are currently no preventative treatment options. Gastrointestinal symptoms are commonly associated comorbidities. The microbiota-gut-brain axis is a multidirectional communication chain that connects the central and enteric nervous system that relates brain function to peripheral intestinal functions. Changes within this axis have been postulated in ASD. For example, the “leaky gut theory” proposes that chronic inflammation is linked to alterations in the bacterial profiles of the gut microbiome and subsequent …
Autism & Autoimmunity, Clarissa Nelson
Autism & Autoimmunity, Clarissa Nelson
Undergraduate Honors Capstone Projects
My research was for the Honors Capstone, and consisted of familiarizing myself with the vast amount of research in the fields of autism and autoimmunity and how the two may be connected, then going on to design a new project to help acquire more information where these two fields overlap. The official abstract I have written for this new project goes as follows: Our proposed research project is focused primarily in the fields of autism and autoimmunity, and hopes to uncover more evidence that these two fields are related. We believe that autism is an autoimmune disease, and our project …
The Influence Of Over-Ground Versus Treadmill Walking On Gait Mechanics In Children With Autism Spectrum Disorder, Emily Ann Chavez
The Influence Of Over-Ground Versus Treadmill Walking On Gait Mechanics In Children With Autism Spectrum Disorder, Emily Ann Chavez
Open Access Theses & Dissertations
Treadmill (TM) walking may be a way to combat obesity and socio-behavioral barriers associated with children with Autism Spectrum disorder (ASD), though tripping-risk has not yet been assessed for this population through use of spatial-temporal gait analysis. The aim of this project/study was to examine spatial-temporal walking mechanics and lower extremity tripping descriptors between over ground (OG) and TM gait conditions in children with ASD compared to children with neurotypical development (NT). Kinematics data were obtained through tridimensional motion analysis where participants, 10 children with ASD and 9 age- and sexmatched NT controls, were outfitted with retroreflective markers on their …