Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Cell and Developmental Biology (5)
- Developmental Biology (4)
- Biology (3)
- Neuroscience and Neurobiology (3)
- Biochemistry, Biophysics, and Structural Biology (2)
-
- Allergy and Immunology (1)
- Animal Sciences (1)
- Architecture (1)
- Behavioral Neurobiology (1)
- Biochemistry (1)
- Cell Biology (1)
- Cognitive Neuroscience (1)
- Computational Neuroscience (1)
- Developmental Neuroscience (1)
- Ecology and Evolutionary Biology (1)
- Environmental Policy (1)
- Environmental Studies (1)
- Historic Preservation and Conservation (1)
- Immunology and Infectious Disease (1)
- Medical Immunology (1)
- Medical Sciences (1)
- Medical Specialties (1)
- Medicine and Health Sciences (1)
- Molecular Biology (1)
- Ornithology (1)
- Other Ecology and Evolutionary Biology (1)
- Public Affairs, Public Policy and Public Administration (1)
- Recreation, Parks and Tourism Administration (1)
- Social and Behavioral Sciences (1)
- Institution
Articles 1 - 13 of 13
Full-Text Articles in Life Sciences
Identifying And Assessing Conflicts Between Future Development And Current Migratory Bird Habitat Around Farmington Bay, Utah, Aubin A. Douglas
Identifying And Assessing Conflicts Between Future Development And Current Migratory Bird Habitat Around Farmington Bay, Utah, Aubin A. Douglas
All Graduate Plan B and other Reports, Spring 1920 to Spring 2023
Every year, the Great Salt Lake (GSL) and its associated wetlands provide critical habitat for over 250 migratory bird species from both the Pacific and Central Flyways. The GSL borders the Wasatch Front, which is the fastest growing and most populous region in Utah. To support the ever-increasing working population, the government of Utah aspires to increase the robust economic growth of the region through economic incentives and development of infrastructure. As this area continues to develop, greater pressure will be placed on the surrounding natural resources, including the GSL, its wetlands, and the open space and agricultural land that …
Epigenetic Regulation Of Genomic Imprinting During Early Mammalian Embryonic Development, Chelsea Marcho
Epigenetic Regulation Of Genomic Imprinting During Early Mammalian Embryonic Development, Chelsea Marcho
Doctoral Dissertations
Mammalian development involves remarkable changes, starting from a single-cell, totipotent zygote and ending with a developed organism comprised of diverse cells types with distinct morphologies, structures, and functions. Within three days of murine development, the two parental genomes merge into a single nucleus, begin zygotic gene expression, undergo epigenetic remodeling, and make the first lineage decisions. Diversity in cell-types is possible even though cells share the same genome. This diversity is achieved by the tight regulation of differential transcriptional programs. There are many ways these transcriptional programs can be initiated. Epigenetic alterations to the genome can drive transcriptional changes. Epigenetic …
A Comprehensive Catalog Of Post-Translational Modifications Of Drosophila Melanogaster Hox Protein, Sex Combs Reduced, Anirban Banerjee
A Comprehensive Catalog Of Post-Translational Modifications Of Drosophila Melanogaster Hox Protein, Sex Combs Reduced, Anirban Banerjee
Electronic Thesis and Dissertation Repository
During formation of the anterior-posterior axis, Homeotic selector (HOX) proteins determine the identity of Drosophila body segments. HOX proteins are transcription factors that regulate gene expression during development. Besides a highly conserved DNA-binding homeodomain (HD), HOX proteins also contain functionally important, evolutionarily conserved small motifs. These short motifs found in HOX proteins may be Short Linear Motifs (SLiMs). SLiMs are proposed to be sites of phosphorylation and this may regulate the activity of HOX proteins. The primary aim of this work was to develop a comprehensive catalogue of the sites of phosphorylation and other post-translational modifications (PTMs) for Fushi tarazu …
The Inter-Subject Correlation Of Eeg In Response To Naturalistic Stimuli, Samantha S. Cohen
The Inter-Subject Correlation Of Eeg In Response To Naturalistic Stimuli, Samantha S. Cohen
Dissertations, Theses, and Capstone Projects
Inter-subject correlation is a measure of the similarity of the brain activity of a group of people as they respond to the same naturalistic stimulus, typically a story or video, meant to simulate a real world experience. This thesis tests the hypothesis that the correlation of the brain responses of a group of people is indicative of stimulus engagement. The rationale is that the content of the stimulus drives brain activity in a consistent manner, while internal thoughts are divergent and result in uncorrelated activity. The inter-subject correlation (ISC) of neural responses have previously been assessed with fMRI, EEG, and …
Zinc Sunscreens Affect Development Of Strongylocentrotus Purpuratus Embryos, Brittany E. Cunningham, Nikki L. Adams
Zinc Sunscreens Affect Development Of Strongylocentrotus Purpuratus Embryos, Brittany E. Cunningham, Nikki L. Adams
Master's Theses
The growing popularity of physical sunscreens will also lead to an increased release of the ingredients from zinc oxide (ZnO) sunscreens into marine environments. Though zinc (Zn) is a necessary micronutrient in the ocean, greater than natural Zn concentrations are being released into marine environments by use of sunscreens. The extent of the consequences of the addition of Zn to the ocean are not fully understood. We investigated effects of materials released by zinc oxide (ZnO) sunscreens on the development of California purple sea urchin, Strongylocentrotus purpuratus. Embryos developed in various concentrations of Zn, the sources of which included …
Association Of P53 Polymorphisms, Pah-Like Fluorescence, And Developmental Trends In Caught Gulf Menhaden To Crude Oil Exposure Post-Deepwater Horizon Oil Spill: A Holistic Approach, Kevin Luiz Frisina
Capstone Projects/Undergraduate Honors Theses
Environmental pollution is of great concern in the United States. Of special concern is the chronic effects from the exposure to potentially carcinogenic compounds released from episodic environmental disasters (e.g. 911 twin-towers, oil spills). Disasters like the British Petroleum (BP) Deepwater Horizon oil spill in the Gulf of Mexico (GOM), affected many marine organisms, exposing them to crude oil polycyclic aromatic hydrocarbons (PAHs), some of which are known carcinogenic. Despite many marine-based consumer products (e.g. fish oil, animal feed, fertilizer) were known affected by the BP oil spill, bioaccumulation and chronic toxicity of the crude oil PAHs into marine organisms …
Innate Lymphoid Cells: Transcriptional Profiles And Cytokine Developmental Requirements, Michelle Lauren Robinette
Innate Lymphoid Cells: Transcriptional Profiles And Cytokine Developmental Requirements, Michelle Lauren Robinette
Arts & Sciences Electronic Theses and Dissertations
Innate lymphoid cells (ILCs) are a recently discovered lineage of professional cytokine-producing cells that strikingly mirror T cells in transcriptional circuitry and effector functions, but derive from distinct progenitors and do not express recombined antigen-specific receptors. These cells include natural killer (NK) cells, which parallel cytotoxic CD8+ T cells, and three additional classes of ILCs enriched at mucosal surfaces that generate signature cytokines reminiscent of polarized CD4+ helper T cells subsets, called ILC1, ILC2, and ILC3. As ILCs have been implicated in the pathogenesis of colitis, cancer, allergy, and autoimmunity in both human and mouse, understanding the functional capacity of …
Stimulating Canonical Wnt Signaling In Pituitary Progenitors Inhibits Differentiation Of Hormone Cell Types, Tanner F. Coleman
Stimulating Canonical Wnt Signaling In Pituitary Progenitors Inhibits Differentiation Of Hormone Cell Types, Tanner F. Coleman
Senior Theses
The mouse pituitary gland secretes hormones that regulate many physiological processes including growth, stress response, and reproduction. The canonical WNT signaling pathway, activation of which results in nuclear accumulation of β-CATENIN and transcription of target genes including LEF1, is crucial for proper development of the pituitary gland. Pituitary progenitors that lack β-CATENIN at embryonic day of development 8.5 (E8.5) cannot form three of the six cell types of the anterior pituitary that produce growth hormone (GH), thyroid stimulating hormone (TSH), and prolactin (PRL). Additionally, stimulating canonical WNT signaling through creation of degradation-resistant β-CATENIN at E9.5 causes pituitary tumors and results …
The Sh2 Domain-Containing Adaptor Protein Shd Reversibly Binds The Crkl-Sh2 Domain And Knockdown Of Shdb Impairs Zebrafish Eye Development, Brendan Chandler
The Sh2 Domain-Containing Adaptor Protein Shd Reversibly Binds The Crkl-Sh2 Domain And Knockdown Of Shdb Impairs Zebrafish Eye Development, Brendan Chandler
Graduate College Dissertations and Theses
The adaptor protein CT10-Regulator of Kinase (CRK) and the closely related CRK-Like (CRKL) are adaptor proteins that play important roles in many signaling pathways regulating cell proliferation and cell motility. A notable example is their required role in Reelin signaling during development of the laminated structures of the vertebrate central nervous system, including the cerebral cortex, cerebellum, hippocampus, and retina. As adaptors, CRK/CRKL are important in coupling phosphotyrosine signaling to G protein activity to regulate both cell proliferation and changes in the actin cytoskeleton, thereby exerting control over cell motility, and migration. While many proteins that interact with CRK/CRKL have …
Polarity And Competition In The Development Of The Calyx Of Held Terminal In The Medial Nucleus Of The Trapezoid Body In The Mouse, Paul Steven Holcomb
Polarity And Competition In The Development Of The Calyx Of Held Terminal In The Medial Nucleus Of The Trapezoid Body In The Mouse, Paul Steven Holcomb
Graduate Theses, Dissertations, and Problem Reports
In the auditory brainstem, the connection between globular bushy cells of the anteroventral cochlear nucleus and principal cells (PCs) of the medial nucleus of the trapezoid body (MNTB) is created by one of the largest nerve terminals in the central nervous system, the calyx of Held (CH). The characteristics of the CH:MNTB connection—a short developmental period (48-72 hours), accessibility for recording from pre- and postsynaptic components, and clear monoinnervated end point—make this system an ideal model system for studying nervous system development. Model systems undergo stereotyped stages of development, including exuberant overinnervation, competition between terminals, and a refinement of innervation …
The Developmental Implications Of The Regulatory Relationship Between Cjun And Oct4 In Murine Embryonic Stem Cells, Rachel E. Brewer
The Developmental Implications Of The Regulatory Relationship Between Cjun And Oct4 In Murine Embryonic Stem Cells, Rachel E. Brewer
Cal Poly Humboldt theses and projects
As cells transition from the point of fertilization through the process of embryonic development, many molecular changes occur that affect cell fate. At the blastocyst stage, the earliest distinction, two separate cell populations arise. The trophectoderm cells will generate all of the extraembryonic tissues while the inner cell mass will yield all of the embryonic tissues. These cells, which generate the organism, are termed pluripotent at this stage and found within the inner cell mass (ICM). A variety of genetic mechanisms that regulate this event have been characterized. Here, we examined the effect of cJun expression in regulating Oct4, a …
Retinoic Acid Receptor Isoform-Specific Control Of Mouse Salivary Gland Development And Regeneration, Kara Desantis
Retinoic Acid Receptor Isoform-Specific Control Of Mouse Salivary Gland Development And Regeneration, Kara Desantis
Legacy Theses & Dissertations (2009 - 2024)
Controlled expansion and differentiation of progenitor cell populations is essential for organogenesis followed by continued maintenance of the population into and through adulthood. As the K5+ basal cell population is regulated by retinoic acid signaling, we interrogated the contribution of specific RAR isoforms to the regulation of these cells during submandibular salivary gland (SMG) organogenesis and regeneration. Retinoic acid has previously been shown to be involved in the development of the salivary gland, and recently, lack of retinoid signaling has been shown to impact the K5+ population of basal progenitor cells. Since retinoic acid is known to exert stimulatory effects …
Disc1 Knockout Rats Reveal Sexually Dimorphic Patterns Of Impairment Across Development, Stephanie S. Desrochers
Disc1 Knockout Rats Reveal Sexually Dimorphic Patterns Of Impairment Across Development, Stephanie S. Desrochers
Honors Theses
Schizophrenia is a chronic disorder characterized by three symptom categories: positive (hallucinations, delusions), negative (anhedonia, anxiety), and cognitive (sensory processing and memory deficits). We worked with a biallelic deletion of the Disrupted-in-schizophrenia-1 (DISC1) gene in Sprague-Dawley rats to facilitate our understanding of the biological bases of schizophrenia. Mutations of DISC1 are associated with a higher prevalence of schizophrenia. Adult DISC1 knockout, compared to wildtype, rats display features of schizophrenia-like outcomes in rodent models. The present study investigated the progression of the cognitive symptom deficits in prepulse inhibition (PPI), assessing animals at postnatal days 17 (pre-weaning), 26 (post-weaning), 39 (adolescent), and …