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Full-Text Articles in Life Sciences

Proteomic Analysis Of The Response Of Pseudomonas Aeruginosa Pao1 To The Cell To Cell Signaling Molecule Trans, Trans-Farnesol Of Candida Albicans, Shelby L. Jones-Dozier Sep 2008

Proteomic Analysis Of The Response Of Pseudomonas Aeruginosa Pao1 To The Cell To Cell Signaling Molecule Trans, Trans-Farnesol Of Candida Albicans, Shelby L. Jones-Dozier

Biology Dissertations

Nosocomial infections associated with implanted medical- devices are on the rise due to a growing immunocompromised patient population. The organisms of interest in this study are Pseudomonas aeruginosa and Candida albicans. These organisms are opportunistic pathogens and are frequently implicated as the cause of infection and colonization of medical devices. P. aeruginosa is a motile gram-negative bacterium that is able to suppress the growth of C. albicans. Quourm sensing mimicry and biofilm formation on the hyphal surface of C. albicans by P. aeruginosa aids in suppression. C. albicans is a dimorphic fungus capable of quorum sensing with E,E-farnesol and is …


Analysis Of The Cyc1 Promoter In Candida Albicans, Tomica Blocker May 2008

Analysis Of The Cyc1 Promoter In Candida Albicans, Tomica Blocker

McCabe Thesis Collection

Scientists are considering two factors that may be important in the pathogenesis of C. albicans', it's capability to morph from yeast to hyphal phase, and its differences in colony morphology, cell shape, cell surface and cell permeability. (5) Unfortunately, unlike the bacteria, yeasts do not yet have proven virulence factors. However, science is suggesting that some of the major factors which contribute to the virulence of Candida are its ability to form hyphae, its ability to resist phagocytosis, its ability to adhere to epithelial cell surfaces, its ability to grow well at 37 degrees Celsius, and its ability to secrete …