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Articles 1 - 7 of 7
Full-Text Articles in Life Sciences
Characterization Of Kaposi's Sarcoma-Associated Herpesvirus Orf11 As A Possible Dutpase, Christina N. Ramirez
Characterization Of Kaposi's Sarcoma-Associated Herpesvirus Orf11 As A Possible Dutpase, Christina N. Ramirez
Seton Hall University Dissertations and Theses (ETDs)
A dUTPase is a crucial enzyme that hydrolyzes dUTP to dUMP. This reaction prevents the mutagenic or lethal misincorporation of uracil into DNA. For that reason, the enzyme is required for efficient DNA replication. Previous studies have shown that has ORFl l dUTPase-like motifs and thus may be a dUTPase. Generally, gammaherpesviruses contain six characteristic dUTPase motifs. In particular ORFl 1 and contains motifs 1, 2, 4, 6. While the characteristic motifs of gamroaberpesviruses include motifs 1, 2, 3, 4, 5, and 6, the number of dUTPase-like motifs in ORFl 1 's protein sequence is substantial. Thus, ORFl 1 may …
Somatostatin Regulates Raw 264.7 Cell Cytokine Release, Shilpa Swarup
Somatostatin Regulates Raw 264.7 Cell Cytokine Release, Shilpa Swarup
Seton Hall University Dissertations and Theses (ETDs)
Immigrant monocytes and resident macrophages propagate the vertebrate innate immune response through cell migration and cytokine production. Monocytes responding to inflammatory challenge migrate into tissues, and as resident macrophages, release a major pro-inflammatory cytokine, tumor necrosis factor a (TNF-a). Macrophge cytokine synthesis is known to be under both negative and positive regulatory control. Recent studies have shown that somatostatin (SRIF) regulates monocyte and peritoneal macrophages. However, the effects of SRIF on RAW 264.7 cells, a transformed monocyte/macrophage cell line, have not been investigated. In the present study, SRIF effect on cytokine release in LPS stimulated RAW 264. 7 cells was …
Effects Of Maternal Exposure To Lps On The Inflammatory Response In The Offspring, Natalie M. La Sala
Effects Of Maternal Exposure To Lps On The Inflammatory Response In The Offspring, Natalie M. La Sala
Seton Hall University Dissertations and Theses (ETDs)
No abstract provided.
Evaluating Salivary Alpha-Amylase As A Biomarker Fro Stress, Denise L. Alfano
Evaluating Salivary Alpha-Amylase As A Biomarker Fro Stress, Denise L. Alfano
Seton Hall University Dissertations and Theses (ETDs)
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Immuno-Opioid Interaction A Potential Connection, Linda Staikos-Byrne
Immuno-Opioid Interaction A Potential Connection, Linda Staikos-Byrne
Seton Hall University Dissertations and Theses (ETDs)
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Evaluation Of Cortisol And Dhea As Biomarkers For Stress, Jennifer A. Smith
Evaluation Of Cortisol And Dhea As Biomarkers For Stress, Jennifer A. Smith
Seton Hall University Dissertations and Theses (ETDs)
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Degenerate Codon Mutagenesis And Cloning Of G-Protein Coupled Receptor Gene Fusion, Michael J. Sofolarides
Degenerate Codon Mutagenesis And Cloning Of G-Protein Coupled Receptor Gene Fusion, Michael J. Sofolarides
Seton Hall University Dissertations and Theses (ETDs)
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