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Full-Text Articles in Life Sciences

The Effects Of Elevated Co2 And Environmental Variation On Plant Phenotype, Herbivore Performance, And Evolutionary Potential In A Brassicacae Model System, John Michael Landosky Aug 2004

The Effects Of Elevated Co2 And Environmental Variation On Plant Phenotype, Herbivore Performance, And Evolutionary Potential In A Brassicacae Model System, John Michael Landosky

Dissertations

No abstract provided.


Non-Parametric Algorithms For Evaluating Gene Expression In Cancer Using Dna Microarray Technology, Virginie Aris May 2004

Non-Parametric Algorithms For Evaluating Gene Expression In Cancer Using Dna Microarray Technology, Virginie Aris

Dissertations

Microarray technology has transformed the field of cancer biology by enabling the simultaneous evaluation of tens of thousands mRNA expression levels in a single experiment. This technology has been applied to medical science in order to find gene expression markers that cluster diseased and normal tissues, genes affected by treatments, and gene network interactions. All methods of microarray data analysis can be summarized as a study of differential gene expression. This study addresses three questions, 1) the roles of selectively expressed genes for the classification of cancer, 2) issues of accounting for both experimental and biological noise, and 3) issues …


Health Impacts Of Polychlorinated Biphenyls (Pcbs) In Aquatic Organisms, Marla Ann Fisher Apr 2004

Health Impacts Of Polychlorinated Biphenyls (Pcbs) In Aquatic Organisms, Marla Ann Fisher

Dissertations

Polychlorinated biphenyls (PCBs) are a major contaminant of global extent in water resources and aquatic biota. Due to its high lipid solubility, PCBs fail to be degraded and, therefore, continue to bioaccumulate throughout the environment and food chain. To determine the impact of PCBs on the immune system ofaged and juvenile Japanese medaka (Oryzias latipes), fish were injected with the coplanar PCB congener 126 and examined after 3 and 14 days. PCB 126 produced oxidative stress in both age groups of fish 14 days post-injection; however, juvenile medaka appeared more susceptible than aged fish. Humoral immunity, as determined by antibody …