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Life Sciences Commons

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Theses/Dissertations

2004

Zoology

Amphibian metamorphosis

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Full-Text Articles in Life Sciences

The Effects Of Environmentally Relevant Doses Of Perchlorate (Clo4-) On Rana Pipiens Metamorphosis And Development, Andrea N. Golli Jan 2004

The Effects Of Environmentally Relevant Doses Of Perchlorate (Clo4-) On Rana Pipiens Metamorphosis And Development, Andrea N. Golli

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this study was to assess the effects of environmentally relevant concentrations of perchlorate on the development and growth of Rana pipiens. Ammonium perchlorate is a rocket fuel oxidizer that is known to interfere with the function of the thyroid gland and some of the highest United States surface water concentration exists in the Las Vegas Wash, NV. Perchlorate not only blocks the body’s ability to incorporate iodine into T3 and T4 hormones through the sodium iodine symporter system, but also depletes the thyroid glands’ internal stores of iodine. Many of the steps that regulate metamorphosis in amphibians …