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Full-Text Articles in Life Sciences
The Role Of Gdf-3 In Patterning The Early Embryo, Ariel Levine
The Role Of Gdf-3 In Patterning The Early Embryo, Ariel Levine
Student Theses and Dissertations
The central aim of modern embryology is the resolution of the signaling pathways and transcriptional networks that direct embryonic development. After a century of rich experimental embryology, more recent molecular analyses of embryogenesis have revealed that communication between cells drives some of the most important events of development, including cell fate determination, growth, and morphogenesis. Among signaling factors, the TGF-β superfamily regulates all of these phenomena, and is the focus of this work. Despite significant progress in understanding the role of individual TGF-β ligands, their ultimate integration as a pathway is not fully understood and several ligands remain unexplored. In …
Molecular Basis Of Vertebrate Embryonic Migration, Paris A. Skourides
Molecular Basis Of Vertebrate Embryonic Migration, Paris A. Skourides
Student Theses and Dissertations
Embryology aims at understanding how a single fertilized cell develops into a complex multicellular organism. Initially the embryo is no more than a ball of cells where the three primordial layers, the ectoderm, mesoderm and the endoderm are one on top of the other. The three germ layers will go on to form all the tissues and organs of the embryo. For example, the ectoderm will give rise to epidermis and the nervous system; the mesoderm to muscles, the skeletal system, the dermis or inner layer of the skin, the circulatory, excretory, and reproductive systems; and, finally, the endoderm will …