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Full-Text Articles in Life Sciences
Field Theoretic Models Of Deep Inelastic Lepton-Nucleon Scattering, Stephen Blaha
Field Theoretic Models Of Deep Inelastic Lepton-Nucleon Scattering, Stephen Blaha
Student Theses and Dissertations
We investigate the asymptotic behavior of the inelastic electron-nucleon structure functions within the framework of ladder models of the virtual Compton amplitude in the limit | q2 |->oo with w=2q.p/|q2| large and fixed. (q is the electron four-momentum transfer and p the target nucleon momentum.) The leading log-arithmic behavior of the ladder diagrams is obtained by Mellin transform techniques.
Nuclear And Plasma Membrane Properties Of Macrophage Heterokaryons And Hybrids, Siamon Gordon
Nuclear And Plasma Membrane Properties Of Macrophage Heterokaryons And Hybrids, Siamon Gordon
Student Theses and Dissertations
Mouse peritoneal macrophages, which do not synthesize DNA in vitro, were fused with a strain of mouse melanoma cells which proliferates rapidly in vitro. The plasma membrane of the macrophage has specific receptors which enable the cell to ingest antibodycoated sheep red cells and is also rich in a divalent cation dependent adenosine triphosphatase (ATPase) activity. The melanoma cell lacks these macrophage membrane markers. High yields of mouse macrophage-melanoma cell heterokaryons and macrophage-macrophage homokaryons were obtained through the Sendai virus -induced fusion of cells spread on a glass surface. After fusion there was a striking reorganization of cellular architecture by …
Frog Spinal Motoneurons: Their Supraspinal Synaptic Input And Anatomical Localization, William L R Cruce
Frog Spinal Motoneurons: Their Supraspinal Synaptic Input And Anatomical Localization, William L R Cruce
Student Theses and Dissertations
Techniques were developed for maintaining a bullfrog spinal cord in situ and for recording intracellularly from lumbar motoneurons in this preparation. Fibers in the contralateral and ipsilateral lateral funiculi of the spinal cord which originate at or above the calamus scriptorius were found to produce EPSPs in flexor and extensor motoneurons innervating the hindlimb. These EPSPs appeared to be generated monosynaptically on the somas and proximal dendrites of the motoneurons. Chromatolysis was used to map the location of motoneurons· innervating hindlimb muscles in the bullfrog, Rana catesbiana. These motoneurons were located in the dorsolateral cell column of the ventral horn, …
Axonal Transport Of Glycoproteins And Glycolipids In The Goldfish Optic System, David Sholem Forman
Axonal Transport Of Glycoproteins And Glycolipids In The Goldfish Optic System, David Sholem Forman
Student Theses and Dissertations
The goldfish retino-tectal pathway is a convenient experimental system for studying axonal transport. Radioactive precursors are injected into the eye, and radioactivity which is transported in the axons of the retinal ganglion cells can be studied as it moves in the optic nerve and optic tract to the optic tectum, where the optic fibers terminate. For instance, when labeled amino acids are injected into the goldfish eye, labeled proteins synthesized in the retinal ganglion cells are axonally transported in the optic fibers. Two main waves of protein are transported: most of the labeled protein moves slowly at a rate of …
Poliovirus Replication: Interactions With Cytoplasmic Membranes And With Compounds Which Affect Virus Biosynthesis, Anne G. Mosser
Poliovirus Replication: Interactions With Cytoplasmic Membranes And With Compounds Which Affect Virus Biosynthesis, Anne G. Mosser
Student Theses and Dissertations
Picornavirus multiplication is intimately associated with intracellular membranes and affects their production and distribution within the cell. We have shown that the density distribution of cytoplasmic membranes separated by isopycnic centrifugation in discontinuous sucrose gradients is progressively altered after infection of HeLa cells with poliovirus. The most striking change is a very large increase in the smooth microsomal membranes with which viral RNA synthesis is associated. These membranes begin to increase between 2.5 and 3.5 hours after infection, and continue to proliferate late in the virus growth cycle, at a time when cellular protein and nucleic acid syntheses are much …
Blockade Of Acetylcholine Receptors By Cobra Toxin Electrophysiology And Pharmacology, Henry A. Lester
Blockade Of Acetylcholine Receptors By Cobra Toxin Electrophysiology And Pharmacology, Henry A. Lester
Student Theses and Dissertations
Cholinergic transmission has been studied in the presence of a pure polypeptide toxin, of known amino-acid sequence, from cobra venom. For the frog sartorius myoneural junction, micropipette electrodes and on-line computer were used to show that the toxin specifically and irreversibly inactivates postsynaptic acetylcholine (ACh) receptors 0 Raja and Torpedo electroplaques also show nicotinic pharmacology and were similarly affected by the toxin. The toxin failed to affect the muscarinic receptors of the isolated frog heart or the receptors of Aplysia neurons (neither nicotinic nor muscarinic)o These and other observations suggest that the toxin's pharmacological specificity is confined to nicotinic ACh …