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Full-Text Articles in Life Sciences
Monitoring Activity Of Drosophila Larvae: Impedance & Video Microscopy Measures, Ann Simone Cooper, Robin L. Cooper
Monitoring Activity Of Drosophila Larvae: Impedance & Video Microscopy Measures, Ann Simone Cooper, Robin L. Cooper
Biology Faculty Publications
No abstract provided.
Monitoring Heart Rate In Drosophila Larvae By Various Approaches, Sameera Dasari, Robin L. Cooper
Monitoring Heart Rate In Drosophila Larvae By Various Approaches, Sameera Dasari, Robin L. Cooper
Biology Faculty Publications
No abstract provided.
Monitoring Carbon Dioxide Production By Drosophila Larvae, Robin L. Cooper, D. Nicholas Mcletchie
Monitoring Carbon Dioxide Production By Drosophila Larvae, Robin L. Cooper, D. Nicholas Mcletchie
Biology Faculty Publications
No abstract provided.
The N-Terminal Prodomain Of Sv23 Is Essential For The Assembly Of A Functional Vitelline Membrane Network In Drosophila, Anita L. Manogaran, Gail L. Waring
The N-Terminal Prodomain Of Sv23 Is Essential For The Assembly Of A Functional Vitelline Membrane Network In Drosophila, Anita L. Manogaran, Gail L. Waring
Biological Sciences Faculty Research and Publications
The vitelline membrane is a specialized extracellular matrix that surrounds and protects the oocyte. Recent studies indicate that it also serves as a storage site for embryonic pattern determinants. sV23, a major vitelline membrane protein, is essential for the morphogenesis of the vitelline membrane as sV23 protein null mutants lay flaccid, infertile eggs. By analyzing a series of sV23 mutant transgenes in the sV23 protein null genetic background, we have shown that sV23 is secreted as a proprotein in functional excess and that C- and N-terminal prodomains are removed successively, following its deposition in the extracellular space. Although a target …
Drawing Lines In The Sand: Even Skipped Et Al. And Parasegment Boundaries., James B. Jaynes, Miki Fujioka
Drawing Lines In The Sand: Even Skipped Et Al. And Parasegment Boundaries., James B. Jaynes, Miki Fujioka
Department of Biochemistry and Molecular Biology Faculty Papers
The pair-rule segmentation gene even skipped (eve) is required to activate engrailed stripes and to organize odd-numbered parasegments (PSs). The protein product Eve has been shown to be an active repressor of transcription, and recent models for Eve function suggest that activation of engrailed is indirect, but these models have not been fully tested. Here we identify the forkhead domain transcription factor Sloppy-paired as the key intermediate in the initial activation of engrailed by Eve in odd-numbered parasegments. We also analyze the roles of the transcription factors Runt and Odd-skipped in this process. Detailed analysis of engrailed and pair-rule gene …
The Cohesion Protein Ord Is Required For Homologue Bias During Meiotic Recombination, Hayley A. Webber, Louisa Howard, Sharon E. Bickel
The Cohesion Protein Ord Is Required For Homologue Bias During Meiotic Recombination, Hayley A. Webber, Louisa Howard, Sharon E. Bickel
Dartmouth Scholarship
During meiosis, sister chromatid cohesion is required for normal levels of homologous recombination, although how cohesion regulates exchange is not understood. Null mutations in orientation disruptor (ord) ablate arm and centromeric cohesion during Drosophila meiosis and severely reduce homologous crossovers in mutant oocytes. We show that ORD protein localizes along oocyte chromosomes during the stages in which recombination occurs. Although synaptonemal complex (SC) components initially associate with synapsed homologues in ord mutants, their localization is severely disrupted during pachytene progression, and normal tripartite SC is not visible by electron microscopy. In ord germaria, meiotic double strand breaks appear …