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Full-Text Articles in Life Sciences

Supporting Biomedical Research In The Era Of Omics And Precision Medicine, Rolando Garcia-Milian, Denise Hersey, Nathan Rupp Aug 2016

Supporting Biomedical Research In The Era Of Omics And Precision Medicine, Rolando Garcia-Milian, Denise Hersey, Nathan Rupp

Rolando Garcia-Milian


This annual report (2015-2016) provides a continuing view on the position of the Cushing/Whitney Medical Library End-user Bioinformatics Program. Besides the report on the three main areas of training, resources and tools, and consultations, it contains the results of the recent assessment “Information and Needs Assessment for Biomedical Research in the Omics Era” During this period, 741 Yale affiliates attended (out of 1240 registered) the end-user bioinformatics training and presentations organized by the Medical Library.  This year, the number of Ingenuity Pathway Analysis and MetaCore accounts continued to grow. Consequently, the number and length of research support consultations (130 researchers …


Bringing Toxicology Into The 21st Century: A Global Call To Action, Troy Seidle, Martin Stephens Jul 2016

Bringing Toxicology Into The 21st Century: A Global Call To Action, Troy Seidle, Martin Stephens

Martin Stephens, PhD

Conventional toxicological testing methods are often decades old, costly and low-throughput, with questionable relevance to the human condition. Several of these factors have contributed to a backlog of chemicals that have been inadequately assessed for toxicity. Some authorities have responded to this challenge by implementing large-scale testing programmes. Others have concluded that a paradigm shift in toxicology is warranted. One such call came in 2007 from the United States National Research Council (NRC), which articulated a vision of ‘‘21st century toxicology” based predominantly on non-animal techniques. Potential advantages of such an approach include the capacity to examine a far greater …


Analysis Of Rna-Seq Alignments Using Dna Subway Green Line (Computational), Raymond A. Enke May 2016

Analysis Of Rna-Seq Alignments Using Dna Subway Green Line (Computational), Raymond A. Enke

Ray Enke Ph.D.

This class tested protocol will guide students through the steps for the following activities:
  • Review basic steps of RNA-Seq bioinformatics analysis in DNA Subway Green Line
  • View and run basic analytics of RNA-Seq data set in DNA Subway Green Line