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Full-Text Articles in Life Sciences
Discovery And Classification Of Ecological Diversity In The Bacterial World: The Role Of Dna Sequence Data, T. Palys, L. Nakamura, Frederick Cohan
Discovery And Classification Of Ecological Diversity In The Bacterial World: The Role Of Dna Sequence Data, T. Palys, L. Nakamura, Frederick Cohan
Frederick M. Cohan
No abstract provided.
Rna Base-Amino Acid Interaction Strengths Derived From Structures And Sequences, Brooke Lustig, S Arora, R L. Jernigan
Rna Base-Amino Acid Interaction Strengths Derived From Structures And Sequences, Brooke Lustig, S Arora, R L. Jernigan
Brooke S. Lustig
We investigate RNA base-amino acid interactions by counting their contacts in structures and their implicit contacts in various functional sequences where the structures can be assumed to be preserved. These frequencies are cast into equations to extract relative interaction energetics. Previously we used this approach in considering the major groove interactions of DNA, and here we apply it to the more diverse interactions observed in RNA. Structures considered are the three different tRNA synthetase complexes, the U1A spliceosomal protein with an RNA hairpin and the BIV TARTat complex. We use binding data for the base frequencies for the seryl, aspartyl …