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Articles 1 - 17 of 17
Full-Text Articles in Life Sciences
Advances Of Multi-Omics And Its Research Progress In Food, Li Lin, Deng Na, Zhang Bo, Li Hui, Liu Miao, Wang Jian-Hui
Advances Of Multi-Omics And Its Research Progress In Food, Li Lin, Deng Na, Zhang Bo, Li Hui, Liu Miao, Wang Jian-Hui
Food and Machinery
In recent years, omics has received a lot of attention from researchers in the field of food and nutrition because of its prominent role in revealing the mechanisms of complex biochemical actions and macro-regulatory dynamic network systems in living organisms and has been applied to research in the field of food. This paper focuses on the application of genomics, transcriptomics, proteomics and metabolomics in the food field from the basic concept of histology, which is expected to provide a theoretical basis and scientific guidance for the further use of histological tools for food ingredient control, quality improvement and safety mechanism …
Ngly1 Deficiency Affects Glycosaminoglycan Biosynthesis And Wnt Signaling Pathway In Mice, Amy Batten
Ngly1 Deficiency Affects Glycosaminoglycan Biosynthesis And Wnt Signaling Pathway In Mice, Amy Batten
PANDION: The Osprey Journal of Research and Ideas
Individuals affected by NGLY1 Deficiency cannot properly deglycosylate and recycle certain proteins. Even though less than 100 people worldwide have been diagnosed with this rare autosomal recessive condition, thousands are affected by similar glycosylation disorders. Common phenotypic manifestations of NGLY1 Deficiency include severe neural and intellectual delay, impaired muscle and liver function, and seizures that may become intractable. Very little is currently known about the various mechanisms through which NGLY1 deficiency affects the body and this has led to a lack of viable treatment options for those afflicted. This experiment uses a loss-of-function (LOF) mouse model of NGLY1 Deficiency homologous …
Commercially Geneticizing Race, Ethnicity, And Nation: The Implications Of The Discourse Surrounding Commercialized Genetic Tests On Identity, Kiara Jacoby
The Compass
No abstract provided.
The Large And Small Of It: The Microbiome And Metagenomics, Austin Hopkins, Elaina Gollmar, Jessica Fernandez, Shawn Wolf, Austin Hilverding, Andrew M. Roecker
The Large And Small Of It: The Microbiome And Metagenomics, Austin Hopkins, Elaina Gollmar, Jessica Fernandez, Shawn Wolf, Austin Hilverding, Andrew M. Roecker
Pharmacy and Wellness Review
Metagenomics, the analysis of the microbial genome, permits scientists to understand the influences of external sources including diet, metabolism and antibiotics on the human microbiome. Research has revealed the possibility of a core symbiosis between humans and bacteria. The main role of the human microbiome is to aid in digestion, but identified ancillary roles include immunologic homeostasis and infection prevention. Quantifying the composition and variability of the microbiome will help lead to future treatments or preventive strategies against unhealthy change. A variety of methods may be used to define the microbiome, and 16S amplicon sequencing is primarily utilized today. Probiotics …
Medicinal And Aromatic Plants In The Omics Era: Application Of Plant Breeding Andbiotechnology For Plant Secondary Metabolite Production, Muzaffer Barut, Muhammad Azhar Nadeem, Özlem Akgür, Leyla Sezen Tansi, Muhammad Aasim, Muhammad Tanveer Altaf, Faheem Shahzad Baloch
Medicinal And Aromatic Plants In The Omics Era: Application Of Plant Breeding Andbiotechnology For Plant Secondary Metabolite Production, Muzaffer Barut, Muhammad Azhar Nadeem, Özlem Akgür, Leyla Sezen Tansi, Muhammad Aasim, Muhammad Tanveer Altaf, Faheem Shahzad Baloch
Turkish Journal of Agriculture and Forestry
Human being has strong and historic connections with plants to fulfill food, feed, and shelter. Moreover, human uses plants as medicine for the treatment of various diseases. Plants are chemical factories for the biosynthesis of the huge number of secondary metabolites (SMs) that are directly used as a medicine or indirectly used in the development of commercial pharmaceutical drugs. Their improvement through classical breeding remains a difficult struggle for plant breeders. Hence, rapidly advancing research on the plant omics era has accelerated our understanding of the complex structure of SMs synthesis in medicinal and aromatic plants (MAPs). In addition, sequencing …
Regenerative Rehabilitation And Genomics: Implications For Occupational Therapy, John V. Rider
Regenerative Rehabilitation And Genomics: Implications For Occupational Therapy, John V. Rider
The Open Journal of Occupational Therapy
The completion of the human genome project has paved the way for health care practitioners to use genetic and environmental information to tailor medical treatment. This innovative approach to health care is rapidly evolving, and occupational therapists need to be aware of the impact it will have on future practice. Regenerative rehabilitation is a product of knowledge and techniques from the fields of rehabilitation and regenerative medicine with the common goal to restore function. Occupational therapists have the potential to play a significant role in regenerative rehabilitation research and implementation. The purpose of this article is to (a) increase understanding …
Signature Changes In The Expressions Of Protein-Coding Genes, Lncrnas, And Repeat Elements In Early And Late Cellular Senescence, Gökhan Karakülah, Ci̇hangi̇r Yandim
Signature Changes In The Expressions Of Protein-Coding Genes, Lncrnas, And Repeat Elements In Early And Late Cellular Senescence, Gökhan Karakülah, Ci̇hangi̇r Yandim
Turkish Journal of Biology
Replicative cellular senescence is the main cause of aging. It is important to note that early senescence is linked to tissue regeneration, whereas late senescence is known to trigger a chronically inflammatory phenotype. Despite the presence of various genome-wide studies, there is a lack of information on distinguishing early and late senescent phenotypes at the transcriptome level. Particularly, the changes in the noncoding RNA portion of the aging cell have not been fully elucidated. By utilising RNA sequencing data of fibroblasts, hereby, we are not only reporting changes in gene expression profiles and relevant biological processes in the early and …
Characterizing Microsatellite Polymorphisms Using Assembly-Based Andmapping-Based Tools, Gülfem Demi̇r, Can Alkan
Characterizing Microsatellite Polymorphisms Using Assembly-Based Andmapping-Based Tools, Gülfem Demi̇r, Can Alkan
Turkish Journal of Biology
Microsatellite polymorphism has always been a challenge for genome assembly and sequence alignment due to sequencing errors, short read lengths, and high incidence of polymerase slippage in microsatellite regions. Despite the information they carry being very valuable, microsatellite variations have not gained enough attention to be a routine step in genome sequence analysis pipelines. After the completion of the 1000 Genomes Project, which aimed to establish the most detailed genetic variation catalog for humans, the consortium released only two microsatellite prediction sets generated by two tools. Many other large research efforts have failed to shed light on microsatellite variations. We …
The Search For A Hero Gene: Fact Or Fiction?, Olivia Efthimiou
The Search For A Hero Gene: Fact Or Fiction?, Olivia Efthimiou
Heroism Science
The radical entry of heroism research into scientific inquiry presents interesting challenges and possibilities for the study of heroism and the human condition more broadly. This ‘final frontier’ of the enduring phenomenon of heroism stands to offer remarkable, unprecedented, and controversial advances in our understanding of heroic and human behaviour. Is a genetic basis for heroism a real possibility? If so, what would its impacts be? Advances in genomics and increased interest in the fields of epigenetics and neuroplasticity might hold the key to its discovery. This article considers some of the leading emerging research in global health genomics and …
Life In The Underworld: Anchialine Cave Biology In The Era Of Speleogenomics, Jorge L. Pérez-Moreno, Thomas M. Iliffe, Heather D. Bracken-Grissom
Life In The Underworld: Anchialine Cave Biology In The Era Of Speleogenomics, Jorge L. Pérez-Moreno, Thomas M. Iliffe, Heather D. Bracken-Grissom
International Journal of Speleology
Anchialine caves contain haline bodies of water with underground connections to the ocean and limited exposure to open air. Despite being found on islands and peninsular coastlines around the world, the isolation of anchialine systems has facilitated the evolution of high levels of endemism among their inhabitants. The unique characteristics of anchialine caves and of their predominantly crustacean biodiversity nominate them as particularly interesting study subjects for evolutionary biology. However, there is presently a distinct scarcity of modern molecular methods being employed in the study of anchialine cave ecosystems. The use of current and emerging molecular techniques, e.g., next-generation sequencing …
Breeding Objectives Indicate Value Of Genomics For Beef Cattle, M. D. Macneil
Breeding Objectives Indicate Value Of Genomics For Beef Cattle, M. D. Macneil
Kansas Agricultural Experiment Station Research Reports
Genomics may have much to offer in the implementation of breeding objectives. Advantages of genomic prediction include increased accuracy of expected progeny differences (EPDs) for traits that have been components of routine genetic evaluations. Perhaps more importantly, genomic prediction makes it possible to include traits that are too costly or too difficult to measure, and traits that are measured too late in life or are sex-limited such that candidates for selection cannot have EBV with high accuracy at the time when selection decisions are made. Genomically enhanced EPDs may also allow for a marked reduction in generation interval, thus accelerating …
Recent Advances In Potato Genomics, Transcriptomics, And Transgenicsunder Drought And Heat Stresses: A Review, Emre Aksoy, Ufuk Demi̇rel, Zahi̇de Nesli̇han Öztürk, Sevgi̇ Çalişkan, Mehmet Emi̇n Çalişkan
Recent Advances In Potato Genomics, Transcriptomics, And Transgenicsunder Drought And Heat Stresses: A Review, Emre Aksoy, Ufuk Demi̇rel, Zahi̇de Nesli̇han Öztürk, Sevgi̇ Çalişkan, Mehmet Emi̇n Çalişkan
Turkish Journal of Botany
Sustainable potato production practices are crucial for food security and social sustainability in the future since potato is a highly nutritious food and it is considered as one of the most promising crops to reduce human hunger and poverty in the world due to its high yield potential. However, being a temperate crop, potato is exposed to various environmental stresses, including extended periods of drought and heat. The majority of potato genomics, transcriptomics, and transgenics studies concentrate on the characterization of molecular mechanisms governing cold hardiness of tubers and response and tolerance mechanisms against diseases. Likewise, potato breeding studies focus …
Genetic Improvement Made Through Dna Testing And Artificial Insemination To High- Growth, High Carcass Value Angus Sires, L C. Grimes, L. R. Corah, T. Brink, M. R. Gardiner, A. K. Sexten
Genetic Improvement Made Through Dna Testing And Artificial Insemination To High- Growth, High Carcass Value Angus Sires, L C. Grimes, L. R. Corah, T. Brink, M. R. Gardiner, A. K. Sexten
Kansas Agricultural Experiment Station Research Reports
The beef industry has improved the recording of pedigrees and performance data through the use of breed associations and herd health databases. Constant evaluation of genetics and performance has allowed producers to make more informed breeding decisions that help improve herd productivity. As a result of recent droughts and elevated feed and grain prices, however, the American beef cowherd is at a record-low 29 million head. For the United States to continue to be the leading producer of beef in the world, the industry must adopt technologies that improve efficiency of the cowherd and the quality of beef being produced. …
The Complete Plastid Genome Sequence Of Iris Gatesii (Section Oncocyclus), A Bearded Species From Southeastern Turkey, Carol A. Wilson
The Complete Plastid Genome Sequence Of Iris Gatesii (Section Oncocyclus), A Bearded Species From Southeastern Turkey, Carol A. Wilson
Aliso: A Journal of Systematic and Floristic Botany
Iris gatesii is a rare bearded species in subgenus Iris section Oncocyclus that occurs in steppe communities of southeastern Turkey. This species is not commonly cultivated, but related species in section Iris are economically important horticultural plants. The complete plastid genome is reported for I. gatesii based on data generated using the Illumina HiSeq platform and is compared to genomes of 16 species selected from across the monocotyledons. This Iris genome is the only known plastid genome available for order Asparagales that is not from Orchidaceae. The I. gatesii plastid genome, unlike orchid genomes, has little gene loss and rearrangement …
Chromosome Evolution In Cyperales, Eric H. Roalson, Andrew G. Mccubbin, Richard Whitkus
Chromosome Evolution In Cyperales, Eric H. Roalson, Andrew G. Mccubbin, Richard Whitkus
Aliso: A Journal of Systematic and Floristic Botany
Karyotypic evolution is a prominent feature in the diversification of many plants and animals, yet the role that chromosomal changes play in the process of diversification is still debated. At the diploid level, chromosome fission and/or fusion are necessary components of chromosomal structural change associated with diversification. Yet the genomic features required for these events remain unknown. Here we present an overview of what is known about genomic structure in Cyperales, with particular focus on the current level of understanding of chromosome number and genome size and their impact in a phylogenetic context. We outline ongoing projects exploring genomic structure …
Phylogeny, Genome Size, And Chromosome Evolution Of Asparagales, J. Chris Pires, Ivan J. Maureira, Thomas J. Givnish, Kenneth J. Systma, Ole Seberg, Gitte Peterson, Jerrold I. Davis, Dennis W. Stevenson, Paula J. Rudall, Michael F. Fay, Mark W. Chase
Phylogeny, Genome Size, And Chromosome Evolution Of Asparagales, J. Chris Pires, Ivan J. Maureira, Thomas J. Givnish, Kenneth J. Systma, Ole Seberg, Gitte Peterson, Jerrold I. Davis, Dennis W. Stevenson, Paula J. Rudall, Michael F. Fay, Mark W. Chase
Aliso: A Journal of Systematic and Floristic Botany
Asparagales are a diverse monophyletic order that has numerous species (ca. 50% of monocots) including important crop plants such as Allium, Asparagus, and Vanilla, and a host of ornamentals such as irises, hyacinths, and orchids. Historically, Asparagales have been of interest partly because of their fascinating chromosomal evolution. We examine the evolutionary dynamics of Asparagales genomes in an updated phylogenetic framework that combines analyses of seven gene regions (atp1, atpB, matK, ndhF, rbcL, trnL intron, and trnL-F intergenic spacer) for 79 taxa of Asparagales and outgroups. Asparagales genomes are evolutionarily labile for …
The Impact Of Genomics And Genetics On Wheat Quality Improvement, John Snape, Lesley Fish, David Leader, Robert Bradburne, Adrian Turner
The Impact Of Genomics And Genetics On Wheat Quality Improvement, John Snape, Lesley Fish, David Leader, Robert Bradburne, Adrian Turner
Turkish Journal of Agriculture and Forestry
This paper discusses how genetic and genomic tools may be used to understand the genetical and molecular control of cereal quality and to develop tools for its manipulation by conventional and genetic engineering approaches. Comprehensive genetic maps are a first step in the genetical and molecular analysis of traits and these now allow the dissection of the genetical control of complex traits. As an example, data on the genetical control of grain protein content in UK winter wheats is presented. From a series of field trials, several potentially useful new QTLs were identified on chromosomes 2B, 5D, 6A, 6B, 7A …