Life Sciences Commons^™

Voluntary Exercise Reduces Alzheimer’S-Like Pathology After Inflammation In Mice, Marielle K. Weintraub, Jordon D. White, Stephanie M. Turner, Samantha L. Hodges, Amanda Leigh Morin, Lindsey N. Sadler, Gary W. Boehm, Michael J. Chumley

International Journal of Exercise Science: Conference Proceedings

Current global statistics estimate that 44.4 million people are afflicted with dementia, and that 50%-75% of these patients suffer from Alzheimer’s disease (AD; Prince et al. 2013). AD, a progressive disorder categorized by neuronal and behavioral deterioration, is the 6^th leading cause of death in America (Alz facts and figure 2012). One hallmark pathology of AD is the presence of amyloid-beta (Aβ) in the brain, which can limit cell-to-cell communication, leading to cognitive deficits, and neuronal cell death. Although the exact origins of this disease still remain unknown, one possible catalyst of AD pathology is inflammation. Our lab has …

Effect Of Extracted Garlic Powder Ingestion For Two Months On Exercise-Induced Immunological Responses, Ayaka Sunami, Hiroshi Tamura, Mikako Sunaga, Naoki Katori, Akira Yokota, Syuichi Kusano, Toshiaki Kodama, Takahiro Yoshizaki, Yuri Yokoyama, Ayumi Nakai, Jyun Yasuda, Yuki Tada, Azumi Hida, Yuko Hasegawa, Yukari Kawano

International Journal of Exercise Science: Conference Proceedings

Introduction. Exhaustive exercise is associated with an increased risk of upper respiratory tract infection. Previously, allicin supplementation has been reported to reduce the incidence of common cold symptoms and production of exercise-induced interleukin (IL)-6. However, it is not clear if daily ingestion of the edible portion of whole garlic (Allium sativum) alters the exercise-induced immunological response. The present study investigated the effects of extracted garlic powder ingestion for 2 months on immune cell counts, natural killer cell activity (NKCA), as well as changes in cytokines, cortisol, and lactic acid in response to high-intensity cycling exercise.

Methods. The present …

Auto Anti Oxldl, Igm And Igg: Comparison Between Sedentary And Athletes, Juliana M B Santos, André L L Bachi, Francisco J O Rios, Tiago L. Capel, Pedro H C Vaisberg, Gislene R. Amirato, Mauro Vaisberg

International Journal of Exercise Science: Conference Proceedings

Introduction: The practice of regular physical activity contributes to reduce the prevalence of coronary hearth disease (CHD) and aerobic exercises are associated with beneficial changes in the profile of circulating lipids and lipoproteins. However in the past years the oxidative hypothesis assumed great importance in the pathogenesis of CHD. During exhaustive exercises there is a greater possibility of oxidation of LDL, forming oxidized LDL (oxLDL) that has a key role in atherogenesis. However the incidence of coronary events in athletes is lower than in sedentary persons. It is described in the literature that we can found in serum auto autoantibodies …

Changes Of Cytokines In Mouse Skeletal Muscle And Plasma By A Single Bout Of Endurance Exercise., Minjung Lee, Noriaki Kawanishi, Koichi Yada, Yungli Hung, Tsubasa Mizokami, Hiroyuki Niihara, Katsuhiko Suzuki

International Journal of Exercise Science: Conference Proceedings

Introduction: Exercise influences some cytokine levels, which is considered the body’s reaction against endogenous stress. Previous human studies demonstrated that high intensity exercise contributes to a dramatic increase of plasma cytokines like Interleukin-6 (IL-6) and Interleukin-1 receptor antagonist (IL-1ra) immediately after exercise. Recently, it has been identified that skeletal muscle produces cytokines and peptides and they exert both paracrine and endocrine effects. However, the sequential changes of cytokine production according to exercise conditions such as intensity, types and working time are still unclear. In this study, we identified the sequential changes of cytokines in both skeletal muscle and plasma after …