Life Sciences Commons^™

Intermittent Feeding Of Tylan Reduces Use Of In-Feed Antibiotics While Still Controlling Incidence Of Liver Abscesses In Finishing Steers, H. C. Muller, R. G. Amachawadi, H. M. Scott, J. S. Drouillard

Kansas Agricultural Experiment Station Research Reports

Liver abscesses are a cause of concern for many feedlots across the country as they lead to a decrease in feedlot performance of finishing cattle as well as a decrease in the final carcass value. Loss in carcass value is due to not only the abscessed liver being condemned, but also due to trim loss associated with the condemned liver. The macrolide drug tylosin phosphate is the drug of choice for metaphylactic treatment of liver abscesses in feedlot cattle. The Food and Drug Administration approved the drug for over-the-counter use, however, from January 2017 all medically important (used in human …

Producer Opinions On Antibiotic Use In The Beef Industry, T. Lee, C. D. Reinhardt, E. F. Schwandt, D. U. Thomson

Kansas Agricultural Experiment Station Research Reports

Antibiotic use in the beef industry is of increasing interest to consumers and has become a point of discussion for producers, veterinarians, and professional scientists in recent years. With the vast amount of information available on the internet and social media, consumers are becoming more knowledgeable about beef production practices and the use of antibiotics in the food animal industries. Furthermore, scientists have devoted a large amount of time and money to research to investigate consumer opinions and perspectives about management practices used in food animal production. However, many of these investigations fail to include the opinions and perspectives of …

Antioxidant Feeding Does Not Impact Incidence Or Severity Of Liver Abscesses, H. C. Muller, C. L. Van Bibber-Krueger, J. S. Drouillard

Kansas Agricultural Experiment Station Research Reports

Liver abscesses are a large source of economic loss in feedlot cattle. Not only do liver abscesses lead to a decrease in feedlot performance, but these livers are condemned in the abattoir and can also lead to a further decrease in carcass value due to trim loss. Tylosin phosphate is a metaphylactic macrolide drug that effectively decreases the occurrence of liver abscesses. The drug is approved by the Food and Drug Administration for over-the-counter use. However, in January 2017 the FDA will require a veterinary feed directive for medically important antibiotics (antibiotics that are used in human health) used in …

Differences In Efficacy Between Gamithromycin, Tilmicosin, And Tulathromycin As Metaphylactic Treatments In High Risk Calves For Bovine Respiratory Disease, T. Miller, M. E. Hubbert, E. F. Schwandt, D. U. Thomson, C. D. Reinhardt

Kansas Agricultural Experiment Station Research Reports

The cost of Bovine Respiratory Disease to the beef industry due to death, poorer conversions, and therapy is estimated to cost more than $3 billion per year. Identifying and mitigating Bovine Respiratory Disease in cattle can be difficult due to the increased susceptibility for Bovine Respiratory Disease in high risk cattle. One management option to minimize an outbreak of respiratory disease is the use of metaphylaxis, the mass treatment of a group of calves to reduce the incidence and adverse effects of respiratory disease on high risk animals. Criteria used to determine the necessity of metaphylactic treatment against Bovine Respiratory …

Route Of Mannheimia Haemolytica And Pasteurella Multocida Vaccine Administration Does Not Affect Health Or Performance Of Receiving Heifers, T. Spore, M. E. Corrigan, T. R. Parks, C. S. Weibert, M. L. Detray, W. R. Hollenbeck, R. N. Wahl, Dale Blasi

Kansas Agricultural Experiment Station Research Reports

Light weight stocker calves often experience health problems shortly after arrival to feeding facilities. Preventative health programs are routinely administered to calves upon arrival to reduce the incidence of Bovine Respiratory Disease. The major route of vaccine administration in cattle is via injection through either intramuscular or subcutaneous routes. Several products have been introduced that utilize the intranasal route of vaccine administration. There are several reasons why intranasal vaccine administration may be more beneficial: 1) Intranasal vaccine administration alleviates concerns that injections pose for Beef Quality Assurance programs. 2) Intranasal vaccine administration may be less stressful on the animal. 3) …

Effect Of Calsporin On Nursing Piglet Growth Performance And Fecal Microflora, M. B. Menegat, C. M. Vier, H. S. Cemin, D. Shawk, J. M. Derouchey, J. C. Woodworth, M. D. Tokach, S. S. Dritz, R. D. Goodband

Kansas Agricultural Experiment Station Research Reports

A total of 26 lactating sows (DNA 241, DNA Genetics, Columbus, NE) and litters were used in a discovery study to evaluate the effects of Calsporin, a direct-fed microbial containingBacillus subtilisC-3102, on fecal microflora of nursing pigs. The treatments consisted of providing a daily oral dose of Calsporin or a placebo control to piglets during the nursing phase. Sows were randomly assigned to treatments based on farrowing date, parity, and initial BW. The treatments were applied individually to piglets once a day from d 2 after farrowing and equalization until weaning on d 19. Sow BW, sow ADFI, …

Identifying Immuno-Dominant And Neutralizing Epitopes From K88 Fimbriae Of Enterotoxigenic Escherichia Coli (Etec), T. Lu, W. Zhang

Kansas Agricultural Experiment Station Research Reports

Enterotoxigenic Escherichia coli (ETEC) bacteria are the primary cause of diarrheal disease, especially porcine post-weaning diarrhea (PWD). Post-weaning diarrhea is one of the most common diseases in piglets 3 to 10 days after weaning and causes the loss of millions of dollars annually to United States swine industry and other countries. These ETEC bacteria produce two types of virulence factors: 1) fimbriae adhesins, which promote bacterial attachment and colonization in pig small intestine; and 2) enterotoxins that disrupt fluid homeostasis and cause fluid hype-secretion and watery diarrhea. The F4 (K88) is the most important fimbria in ETEC bacteria causing PWD. …

Zelnate On Arrival Could Decrease The Likelihood Of Subsequent Pulls In Suspect Bovine Respiratory Disease Complex Cases, T. Spore, S. P. Montgomery, G. A. Hanzlicek, W. R. Hollenbeck, R. N. Wahl, J. E. Sears, Dale Blasi

Kansas Agricultural Experiment Station Research Reports

Antimicrobial metaphylaxis is an important tool used for the prevention of Bovine Respiratory Disease Complex; a disease with a large economic impact that typically affects newly-weaned beef calves that are marketed and transported a distance from their origin.

There are questions involving the potential benefit of Zelnate, a novel non-antibiotic technology designed to activate an animal’s natural immunity to fight Bovine Respiratory Disease Complex, being used either solely or in combination with metaphylaxis at the time of initial processing of high risk calves. More knowledge is also needed regarding the possible effects of repeated use of Zelnate when subsequent therapy …

Twenty-Four Hour Holter Monitoring In Finishing Cattle Housed Outdoors, D. A. Frese, J. D. Thomason, C. D. Reinhardt, S. J. Bartle, D. N. Rethorst, G. H. Loneragan, E. F. Schwandt, D. U. Thomson

Kansas Agricultural Experiment Station Research Reports

Ambulatory electrocardiogram monitoring, in the form of Holter monitoring, has been used in human and veterinary medicine for decades as an aid in the diagnosis and determination of appropriate therapy of heart rhythm disturbances. Within veterinary medicine, Holter monitors have been primarily used in companion animal species, yet little attention has been given to food animal species. Moreover, the heart rhythm in clinically normal cattle fed high concentrate diets and housed outdoors in confined drylot facilities has not been previously reported. In order to properly identify pathologic arrhythmias in cattle, the normal rhythm and arrhythmia prevalence in healthy cattle should …

Quantifying Medium Chain Fatty Acid Mitigation Activity Over Time Against Porcine Epidemic Diarrhea Virus In Nursery Pig Diets, J. T. Gebhardt, J. C. Woodworth, M. D. Tokach, J. M. Derouchey, R. D. Goodband, C. K. Jones, S. S. Dritz

Kansas Agricultural Experiment Station Research Reports

Medium chain fatty acids (MCFA) are six to twelve carbon length molecules that have shown significant promise as potential mitigants of biological hazards in feed and feed ingredients. The use of residual duration of activity approaches, such as MCFA, have significant advantages compared to point-in-time mitigation strategies. The primary advantage of MCFA is the ability to mitigate the risks generated by post-processing contamination; however, the duration of mitigation activity has not been established. Therefore, the objective of this experiment was to characterize the mitigation properties of MCFA-treated swine feed 40 d following feed manufacturing. Treatments (n = 8) consisted of …

Genome Diversity And Molecular Detection Of Prrs Field Strains And Vaccine Strains, And Pcv3 And Pcv2 Strains, Y. Wang, F. Yuan, X. Liu, W. Zheng, H. Zhang, J. Zhang, K. Yoon, L. Peddireddi, Y. Fang, G. Anderson, J. Bai

Kansas Agricultural Experiment Station Research Reports

Molecular diagnosis of porcine reproductive and respiratory syndrome virus (PRRS) and porcine circo virus (PCV) are challenging due to high genetic diversity in the viral genomes. Differentiating PRRS vaccine strains is even more challenging and is currently done by DNA sequencing, which is expensive and time-consuming. A multiplexed system (Luminex) allowing multiple detection targets in the same reaction is available. However, this system is not fully developed for common swine pathogens. Therefore, an assay was built to detect the majority of field PRRS strains by using different pairs of primers, and at the same time, to provide differentiation of the …