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Articles 1 - 30 of 181
Full-Text Articles in Life Sciences
The Effect Of Various Polyphenols On Associative Memory Loss And Dementia In A Drosophila Melanogaster Model Of Alzheimer’S Disease, Anagha Gowda
Journal of the South Carolina Academy of Science
Alzheimer’s Disease (AD), a prominent neurodegenerative disease (NDD), is the seventh leading cause of death in the United States; however, little is known about prevention. As a result, polyphenols (plant-based compounds) and other natural substances have been studied for their therapeutic potential in improving cognition and memory in AD cases. While the impacts of each polyphenol (phenolic acids, flavonoids, stilbenes, and lignans) contain fundamental similarities, each varies slightly in its impacts on the brain.The purpose of this study was to examine the impacts of polyphenol subgroups on associative memory in AD, tested by building an olfactory association, through the use …
The Comparative Impact Of Acesulfame-Potassium, Stevia Extract, And Monk Fruit On The Lifespan Of Drosophila Melanogaster, Beverly Holton
The Comparative Impact Of Acesulfame-Potassium, Stevia Extract, And Monk Fruit On The Lifespan Of Drosophila Melanogaster, Beverly Holton
Journal of the South Carolina Academy of Science
Non-nutritive sweeteners (NNS), non-caloric sweetening devices, have been widely commercialized to reduce sugar consumption. This intent has associated NNS with health benefits, though reports have correlated the consumption of these substitutes with noncommunicable diseases. The interaction between NNS and distinct physiological processes has been examined, though research into the broader implications of these interactions, toward longevity, for instance, is lacking. The purpose of this study was to compare the impact of three recently FDA-approved NNS - acesulfame-Potassium (ace-K), stevia, and monk fruit - on the survival of Drosophila melanogaster, a model species for longevity research, to discern the possible impacts …
The Effect Of Rosmarinus Officinalis And Trachyspermum Ammi On The Growth Of Eruca Vesicaria Ssp. Sativa In Hydroponics Versus Natural Soil, Emna Guedhami
Journal of the South Carolina Academy of Science
Despite technology being developed to address the food shortages due to increasing population, current methods of cultivating crops are not sufficient. Scientists are addressing this issue by researching biostimulants that stimulate plant growth without harming the environment and researching the use of hydroponics, a way of growing crops without soil. The purpose of this study was to combine the use of essential oils and growing methods (hydroponics and soil) and measure its impact on the height of E. sativa. It was hypothesized that if E. sativa was grown hydroponically with added Rosmarinus officinalis (REO) and Trachyspermum ammi (TEO) over time, …
The Effect Of Crystalline Phase On The Toxicity Of Tio2 Nanoparticles To Chlorella, Jisoo Lee
The Effect Of Crystalline Phase On The Toxicity Of Tio2 Nanoparticles To Chlorella, Jisoo Lee
Journal of the South Carolina Academy of Science
Nanoparticles (NPs), or particles with dimensions that go below 100 nanometers, can be released into the environment in various ways, such as through cosmetic products like sunscreen. Titanium dioxide (TiO2) is a commonly used nanoparticle in sunscreen, and it has the potential to be harmful to various aquatic organisms including algae. The purpose of this study was to examine how the crystalline phase of TiO2 NPs (brookite or rutile) influenced their toxicity to the microalgae species Chlorella. It was hypothesized that brookite phase TiO2 NPs would inhibit the growth of Chlorella more than rutile phase TiO …
The Combined And Individual Effects Of Azadirachta Indica L. Oil And Nahco3 On The Inhibition Of F. Oxysporum, Neya Murugesan
The Combined And Individual Effects Of Azadirachta Indica L. Oil And Nahco3 On The Inhibition Of F. Oxysporum, Neya Murugesan
Journal of the South Carolina Academy of Science
F. oxysporum is the causal agent of Fusarium wilt. This disease is known to penetrate the roots of plants and wilt the vascular system. The most common method for control is through the use of synthetic fungicides, which are known to cause adverse effects on the environment and human health. Thus, it is necessary that more methods of biocontrol be explored. Current literature shows that various salts and essential oils are effective for the biocontrol of F. oxysporum. However, the two types of substances have not yet been tested together, causing a gap in current research. Due to the antifungal …
The Effect Of The Addition Of Carrot Seed Oil And Raspberry Seed Oil On The Uv Intensity Of A Sunscreen, Isra Siddique
The Effect Of The Addition Of Carrot Seed Oil And Raspberry Seed Oil On The Uv Intensity Of A Sunscreen, Isra Siddique
Journal of the South Carolina Academy of Science
With continuous developments in research indicating the potential health risks of chemical sunscreen filters, the novel approach of incorporating natural oils with UV light blocking properties has been explored. Natural oils extracted from fruit and vegetables have been proven to possess photoprotective properties, but their effectiveness in combination with synthetic sunscreen filters has not been as thoroughly investigated. The purpose of this study was to determine whether the addition of carrot and raspberry seed oil to an SPF 30 sunscreen would decrease the UV intensity of UVB light passing through the sunscreen and oil mixture. It was hypothesized that if …
The Effect Of Exposure To Lentinula Edodes And Flammulina Velutipes On The Biodegradation Of Crystallized Polylactic Acid, Iraine Taine
The Effect Of Exposure To Lentinula Edodes And Flammulina Velutipes On The Biodegradation Of Crystallized Polylactic Acid, Iraine Taine
Journal of the South Carolina Academy of Science
Crystallized polylactic acid (CPLA) is a prevalent bioplastic which, despite being biodegradable, is extremely resistant to decomposition in natural environments. As a result, CPLA waste contamination is rapidly becoming a prevalent issue. Lentinula edodes and Flammulina velutipes are two widespread white-rot fungi whose capabilities for bioplastic degradation have not been examined. This study aimed to determine a natural approach for reducing plastic waste by evaluating the ability of L. edodes and F. velutipes to degrade CPLA bioplastic. It was hypothesized that CPLA samples would decrease in mass when individually treated with L. edodes and F. velutipes due to their similarities …
Table Of Contents
Journal of the South Carolina Academy of Science
No abstract provided.
Identification Of Regulatory Elements In The Untranslated Regions Of Streptolysin S Associated Gene A Messenger Rna From Group A Streptococcus, Cameron R. Carroll, Sara G. Nibar, Alexis S. Brown, Lauren R. Angello, Gabriela C. Pérez-Alvarado, Brian M. Lee
Identification Of Regulatory Elements In The Untranslated Regions Of Streptolysin S Associated Gene A Messenger Rna From Group A Streptococcus, Cameron R. Carroll, Sara G. Nibar, Alexis S. Brown, Lauren R. Angello, Gabriela C. Pérez-Alvarado, Brian M. Lee
Journal of the South Carolina Academy of Science
Streptococcus pyogenes, also known as group A Streptococcus (GAS), is a human pathogen associated with a variety of diseases such as strep throat, scarlet fever, toxic shock syndrome, and necrotizing fasciitis. One of the virulence factors released by GAS during an invasive infection is a cytotoxic peptide, streptolysin S (SLS), which inhibits the immune response to necrotizing fasciitis. The streptolysin S associated gene A product, SagA, is modified to produce SLS. Thesag operon includes sagA and the genes required for enzyme-mediated post-translational modifications of SagA and the export of SLS. The sagA gene is contained within the pleiotropic …
Environmental Bacteriophage Presence In Drainage Ponds At Coastal Carolina University, Hailey Oldfield, Alexei E. Chesnutwood, Gabriella A. Caldwell, Shiraz C. Cohen, Paul E. Richardson
Environmental Bacteriophage Presence In Drainage Ponds At Coastal Carolina University, Hailey Oldfield, Alexei E. Chesnutwood, Gabriella A. Caldwell, Shiraz C. Cohen, Paul E. Richardson
Journal of the South Carolina Academy of Science
No abstract provided.
Identification Of A Small Regulatory Rna Usps Associated With The Universal Stress Protein In Lactobacillus Species, Zarah M. Fowler, Sasha S. Bronovitskiy, Finn K. Rose, Brian M. Lee
Identification Of A Small Regulatory Rna Usps Associated With The Universal Stress Protein In Lactobacillus Species, Zarah M. Fowler, Sasha S. Bronovitskiy, Finn K. Rose, Brian M. Lee
Journal of the South Carolina Academy of Science
The gut microbiome is a complex habitat with many bacterial species, each playing crucial roles in regulating various physiological processes in the body. As the use of probiotics to combat human disease continues to increase, it is important to understand the mechanisms by which probiotic bacteria regulate their interactions with other bacteria and their host. Our exploration of the physiological functions of probiotic bacteria hopes to elucidate the role of small regulatory RNA (sRNA) in regulating gene expression within the microbiome. The goal of this project was to characterize the structure and function of the sRNA, UspS, which is found …
Developing A Safe And Effective Papillomavirus Screen To Be Used On College Students At A South Carolina University, Owen R. Smith, Nicole E. Frantz, Emily E. Bishop, Rahjai G. Thomas, Paul E. Richardson
Developing A Safe And Effective Papillomavirus Screen To Be Used On College Students At A South Carolina University, Owen R. Smith, Nicole E. Frantz, Emily E. Bishop, Rahjai G. Thomas, Paul E. Richardson
Journal of the South Carolina Academy of Science
No abstract provided.
Table Of Contents
Journal of the South Carolina Academy of Science
No abstract provided.
A Most Surprising Fern: Serendipity And Browsing In Botanical Search, Douglas Tuers
A Most Surprising Fern: Serendipity And Browsing In Botanical Search, Douglas Tuers
Journal of the South Carolina Academy of Science
This article is a case study of botanical field work in the eastern United States in the early twentieth century. These cases will be analyzed as instances of browsing and serendipity. Browsing and serendipity have a rich literature in information science and this article will draw on this literature in order to better understand serendipity in botany. This article will show how botanical localities support browsing and serendipity for the botanists who search them. This article will also show how botanical institutions and botanists interface with localities in order to further support browsing and serendipity. As a whole this article …
Consolidated Chamber Design And Protocol For Olfactory Conditioning Assay With Drosophila Melanogaster, Sasha Bronovitskiy, Andres Castillo, Michael Yan, Fang Ju Lin
Consolidated Chamber Design And Protocol For Olfactory Conditioning Assay With Drosophila Melanogaster, Sasha Bronovitskiy, Andres Castillo, Michael Yan, Fang Ju Lin
Journal of the South Carolina Academy of Science
The olfactory conditioning assay is widely used in Alzheimer’s disease research to quantify learning and memory in Drosophila melanogaster. The assay tests ability to recall an aversive conditioned stimulus of scent paired with electrical shock when presented a choice between shock-associated and unrelated scents. The T-maze, a commonly used apparatus for olfactory conditioning assays, employs an elevator mechanism to transfer live flies from the shock-delivering training chamber to the scent selection point. This elevator mechanism is known to cause fly casualty. T-mazes are not commercially available and often difficult to reproduce. Other existing variations of olfactory conditioning apparatuses use …
Table Of Contents
Journal of the South Carolina Academy of Science
No abstract provided.
The Effects Of Salinity And Acetaminophen On The Aquatic Snail Physa Acuta, Michelle Sackey-Ansah, Megan Mackey, Daniel Elias, Jason Doll, Alyssa Brookhart
The Effects Of Salinity And Acetaminophen On The Aquatic Snail Physa Acuta, Michelle Sackey-Ansah, Megan Mackey, Daniel Elias, Jason Doll, Alyssa Brookhart
Journal of the South Carolina Academy of Science
Pharmaceuticals are increasingly detected in water bodies, and their presence can negatively impact aquatic organisms. This effect can be amplified when combined with increasing salinity in freshwater ecosystems. Acetaminophen is a widely used analgesic that is commonly found in river, streams, and waters where it is discharged directly. Therefore, organisms present in these locations (e.g., insects, snails, amphibians, and fish) are likely to be affected by acetaminophen. In this study, we determined the effects of elevated salinity (0.68 g/L), acetaminophen (500 µg/L) and combined elevated salinity (0.68 g/L) and acetaminophen (500 µg/L), on the growth, reproduction, and movement of the …
The Phytoremediation Of Escherichia Coli In Contaminated Water By Lemna Minor, Salvinia Minima, And Azolla Caroliniana, Madison Han
Journal of the South Carolina Academy of Science
No abstract provided.
The Effectiveness Of Lithium Chloride In Eliciting A Taste Aversion Response In Blaptica Dubia, Ava Phelps
The Effectiveness Of Lithium Chloride In Eliciting A Taste Aversion Response In Blaptica Dubia, Ava Phelps
Journal of the South Carolina Academy of Science
No abstract provided.
The Effect Of Spirulina Major And Oscillatoria On Reducing The Acidity Of Freshwater Containing Antibacterial Liquid And Bar Soaps ., Kartik Valluri
The Effect Of Spirulina Major And Oscillatoria On Reducing The Acidity Of Freshwater Containing Antibacterial Liquid And Bar Soaps ., Kartik Valluri
Journal of the South Carolina Academy of Science
No abstract provided.
The Effects Of Rice Bran Oil As A Repellent For Aedes Aegypti Compared To Mineral Oil And Effective Natural Repellents, Aleena Chattha
The Effects Of Rice Bran Oil As A Repellent For Aedes Aegypti Compared To Mineral Oil And Effective Natural Repellents, Aleena Chattha
Journal of the South Carolina Academy of Science
No abstract provided.
3,6-Dimethoxyxanthone From 2,2’,4,4’- Tetrahydroxy-Benzophenone Via Microwave-Assisted Annulation, Sarah E. Knisely, Faith R. Rosario, Salem F. Gebeyehu, Paige E. Heiple, Robert E. Lee Sr
3,6-Dimethoxyxanthone From 2,2’,4,4’- Tetrahydroxy-Benzophenone Via Microwave-Assisted Annulation, Sarah E. Knisely, Faith R. Rosario, Salem F. Gebeyehu, Paige E. Heiple, Robert E. Lee Sr
Journal of the South Carolina Academy of Science
Xanthones are tricyclic aromatic compounds that have multiple pharmacological uses due to their anti-tumor, antioxidant, anti-inflammatory, anti-bacterial, and potentially chemopreventive properties. The target of this research was to optimize a two-step synthesis of 3,6-dimethoxyxanthone (3) from 2,2’,4,4’-tetrahydroxy-benzophenone (1) via microwave-assisted (200 °C, 30-40 min., 150 W) sodium acetate-catalyzed annulation. The product, 3,6-dihydroxyxanthone (2), was then methylated to (3) using dimethyl sulfate (DMS) and sodium carbonate in acetone at reflux. The product yields were 93% (>99% purity) for (2) and 94% (>99% purity) for (3). Characterization was accomplished using 1H NMR, FTIR, melting point, TLC, HPLC, and GCMS. …
2022 Scas Annual Meeting Program And Bulletin
2022 Scas Annual Meeting Program And Bulletin
Journal of the South Carolina Academy of Science
No abstract provided.
Salt Marsh Plant Community Structure On Horse Island, South Carolina, Mackenzie L. Jenkins, Jennifer L. Schafer
Salt Marsh Plant Community Structure On Horse Island, South Carolina, Mackenzie L. Jenkins, Jennifer L. Schafer
Journal of the South Carolina Academy of Science
Sea level rise is causing an increase in salt water encroachment and flooding in many coastal habitats, and increasing salinity can have negative impacts on plant communities. The objective of our research was to determine the impact of salinity on salt marsh plant community structure on Horse Island, South Carolina. We investigated variation in plant cover and height with distance from a tidal creek and the effect of increasing salinity on seedling emergence from the seed bank. We established three transects in the salt marsh habitat and recorded plant species presence, percent cover of each species, and height of the …
Alu Dimorphism At The Pv92 Locus Of Chromosome 16 Is In Equilibrium For University Student Population, James M. Brooks, Mackenzie L. Thackston
Alu Dimorphism At The Pv92 Locus Of Chromosome 16 Is In Equilibrium For University Student Population, James M. Brooks, Mackenzie L. Thackston
Journal of the South Carolina Academy of Science
Alu is a retrotransposable element, which refers to its ability to be copied and move from one region of DNA to another DNA region. At the PV92 locus of chromosome 16, Alu is a 300 bp dimorphic insert that can either be present or absent. It does not encode a protein product and has lost the ability to transpose. It is specific to humans, and differences in genotype and allele frequencies between human populations are important tools in understanding evolution. In this research, data was obtained and analyzed from 269 students at Charleston Southern University (CSU) belonging to four different …
Environmental Bacteriophage Detection On Coastal Carolina University Campus, Madison Gentilo, Hailey Oldfield, Gavin Ockert, Paul E. Richardson
Environmental Bacteriophage Detection On Coastal Carolina University Campus, Madison Gentilo, Hailey Oldfield, Gavin Ockert, Paul E. Richardson
Journal of the South Carolina Academy of Science
Bacteriophages are viruses that infect bacteria. These viruses are found ubiquitously in the environment and are more abundant than any living organism on Earth, including bacteria. Eleven sites are designated for weekly sample collection on the campus of Coastal Carolina University. Water samples are filtered and amplified using strains of E. coli B and E. coli K12 to allow potential coliphages in the sample to proliferate to detectable levels. Plaque assays are used as a microbial screen for the presence of bacteriophage. Samples that test positively using the microbial test are analyzed through a molecular test using PCR to identify …
The Effects Of Human Behavioral Changes Due To The Covid-19 Pandemic On The Reservoir Of Lytic Escherichia Coli And Staphylococcus Aureus Bacteriophage On Humans At A South Carolina University, Korinne M. Swanson, Owen R. Smith, Paul E. Richardson
The Effects Of Human Behavioral Changes Due To The Covid-19 Pandemic On The Reservoir Of Lytic Escherichia Coli And Staphylococcus Aureus Bacteriophage On Humans At A South Carolina University, Korinne M. Swanson, Owen R. Smith, Paul E. Richardson
Journal of the South Carolina Academy of Science
Bacteriophages are viruses, whose unique ability to infect and lyse bacterial cells may provide valuable insight for evading the repercussions of a post-antibiotic era in medicine. This study isolated and characterized Escherichia coli and Staphylococcus aureus bacteriophage on students and faculty at Coastal Carolina University as a means to understand the viability of human bacteriophage reservoirs for bacteriophage therapy. From September 2021 to March 2022, nasal and postauricular swab samples and a behavioral survey were collected from ninety-three randomly selected participants. Additionally, sixteen participants contributed nasal and postauricular swab samples and a behavioral survey on a monthly basis in a …
Table Of Contents
Journal of the South Carolina Academy of Science
No abstract provided.
Table Of Contents
Journal of the South Carolina Academy of Science
No abstract provided.
Intramolecular Friedel-Crafts Addition Of Indoles To Tertiary Allylic Alcohols, Bryan H. Wakefield, Romie Barnes, Traeannah Brown, Ashley M. Jones, Victoria A. Knotts, Christina Martinetti
Intramolecular Friedel-Crafts Addition Of Indoles To Tertiary Allylic Alcohols, Bryan H. Wakefield, Romie Barnes, Traeannah Brown, Ashley M. Jones, Victoria A. Knotts, Christina Martinetti
Journal of the South Carolina Academy of Science
An intermolecular Friedel-Crafts alkylation of indole and tertiary allylic alcohols has been developed. The allylic alcohols were synthesized using a two-step procedure, then exposure of these alcohols to diphenyl phosphate facilitated the desired annulation reaction. This reaction tolerated a variety of indole substitutions to yield 1H,2H,3H,4H-pyrido[1,2-a]indoles.