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Articles 1 - 7 of 7
Full-Text Articles in Life Sciences
Secondary Metabolite Production And Biological Activity Of Endophytic Microbes Of Mahonia Aquifolium, Christopher Rufus Sweeney, Bradley Geary
Secondary Metabolite Production And Biological Activity Of Endophytic Microbes Of Mahonia Aquifolium, Christopher Rufus Sweeney, Bradley Geary
Journal of Undergraduate Research
Secondary metabolites are a result of natural evolutionary mechanism used to aid in plant development and defense, and the research of these metabolites have led to important discoveries in medicines, pesticides and even fossil fuels. In this project, we studied secondary metabolites of microorganisms in Mahonia aquifolium, otherwise known as Oregon grape. This plant is known to produce the chemical compound berberine as a secondary metabolite. Berberine has been shown to have similar effects to metformin and other diabetes treatments, as well as a host of other medicinal qualities. We looked at endophytic fungi and bacteria to see if they, …
Examination And Classification Of Secondary Metabolites From Endophytes Of Cornus Sericea, Madsen Sullivan, Brad Geary
Examination And Classification Of Secondary Metabolites From Endophytes Of Cornus Sericea, Madsen Sullivan, Brad Geary
Journal of Undergraduate Research
All civilizations have used plants and their byproducts to effectively grow and cultivate crops, as well as manage and treat many ailments. Even today, approximately 25% of prescribed medications are constituted by plants. Many of the active metabolites are produced in such small quantities that mass production by using the plant is unreasonable. However, the endophytes found within plants tend to produce the same metabolites. These fungi and bacteria commonly produce secondary metabolites possessing antibacterial, antifungal or other medicinal properties. By looking to historical medicinal plants, novel endophytes and metabolites have been discovered and integrated into agriculture and medicine. One …
The Effect Of Gut Microbiota On Starvation Resistance In D. Melanogaster, Alec Judd, John Chaston
The Effect Of Gut Microbiota On Starvation Resistance In D. Melanogaster, Alec Judd, John Chaston
Journal of Undergraduate Research
It has already been established that gut microbiota affect starvation resistance, fat (TAG) content, and development in D. melanogaster. Previous studies in this lab have suggested that effects of the microbiome on these traits are correlated, but this prediction has not been explicitly tested. We are specifically interested in identifying individual bacterial genes that may mediate microbial effects on all three host traits. One way to identify genes with causal influence on animal traits is MGWA (Meta Genome-Wide Association). To this end we have measured starvation resistance in D. melanogaster individually associated with a panel of 43 bacterial strains, and …
Optimization Of The Memory Protocol And Investigation Of Camp Levels In Axenic And Conventional Flies, Toree Lammel, John Chaston
Optimization Of The Memory Protocol And Investigation Of Camp Levels In Axenic And Conventional Flies, Toree Lammel, John Chaston
Journal of Undergraduate Research
Going into this project, it was my intention of complete two separate goals: first, to optimize a learning assay for testing memory and learning in Drosophila melanogaster for future use in the Plant and Wildlife Department laboratory at Brigham Young University, and second, to investigate cyclic AMP (cAMP) levels between two genotypes of Drosophila: wild type and dunce. While I was able to successfully complete my first goal, due to unexpected complications while completing it, the second goal was unable to be completed in time. This experience has taught me that experiments can be difficult to work into a specific …
Effects Of Host Microbiota On Intestinal Fiber Content, Kyle Olsen, John Chaston
Effects Of Host Microbiota On Intestinal Fiber Content, Kyle Olsen, John Chaston
Journal of Undergraduate Research
As a pseudo-ruminant, the alpaca is highly dependent on the bacteria in its intestinal tract to obtain the nutrients it needs. For example the starch-fermenting bacteria in the compartment 1 (C1) access nutrients from the normally indigestible starches the alpaca consumes. The bacteria release volatile fatty acids (VFAs) in return. The alpaca uses VFAs as a source of energy. In turn, the composition of the microbiome (bacteria in the intestinal tract) is affected by many factors involving its host. These factors could include host genome, diet, and location in the digestive tract. Our research was to survey many aspects of …
The Effect Of Promoter Region Indels On Expression Bias In Polyploid Cotton Species, Zachary Liechty, Joshua Udall
The Effect Of Promoter Region Indels On Expression Bias In Polyploid Cotton Species, Zachary Liechty, Joshua Udall
Journal of Undergraduate Research
Many plants undergo polyploidization events throughout their history, meaning their genome doubles1; the goal of this project was to identify how these polyploidization events lead to changes in gene expression on a nucleotide level. Polyploidization events provide raw material to be acted upon by natural selection, allowing evolution to occur. Now with four copies of a gene instead of two, mutations can occur or expression levels can change without too great an influence on the plants well-being. This project examines factors relating to changes in gene expression between subgenomes after a polyploidization event among different cotton species. We …
Gene Discovery: Understanding Oat Biosynthetic Pathways Through Characterization Of The Adp-Glucose Pyrophosphorylase Gene, Evan Braithwaite, Eric Jellen
Gene Discovery: Understanding Oat Biosynthetic Pathways Through Characterization Of The Adp-Glucose Pyrophosphorylase Gene, Evan Braithwaite, Eric Jellen
Journal of Undergraduate Research
Grains that are high in soluble hemicellulose fiber, such as oat, provide numerous health benefits to consumers. These benefits include decreased risk of heart disease and lowered cholesterol. For this reason, information regarding genes that are involved in regulating starch and fiber synthesis in oat is highly valuable to breeders and cereal companies. However, because of the polyploid nature (allohexaploidy) and intrinsic complexity of the oat genome, given its propensity for chromosomal rearrangement, genetic data available for use in further research is limited, with many important regions still unsequenced. One such region is the gene coding for adenosine diphosphoglucose pyrophosphorylase …