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Full-Text Articles in Life Sciences
Does Preimplantation Genetic Testing Increase The Risk Of Adverse Clinical Outcomes?, Robyn Weiss
Does Preimplantation Genetic Testing Increase The Risk Of Adverse Clinical Outcomes?, Robyn Weiss
The Science Journal of the Lander College of Arts and Sciences
Before 1990, options were limited for couples who were at risk for transmitting a genetic disease or a structural chromosomal abnormality to their children. Couples traditionally underwent invasive procedures such as amniocentesis and chorionic villus sampling, after which termination was offered if the fetus was found to be affected. Many couples chose not to have children at all. Since then, technological advances have allowed preimplantation genetic testing (PGT) to be offered to these couples. Couples who choose PGT undergo in-vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI), where the oocyte is injected by a single sperm and is then implanted …
What Role Does Age-Associated Neuroplasticity Play In The Efficacy Of Cochlear Implantation?, Jacob Fliegelman
What Role Does Age-Associated Neuroplasticity Play In The Efficacy Of Cochlear Implantation?, Jacob Fliegelman
The Science Journal of the Lander College of Arts and Sciences
Bilateral, profound-severe, congenital deafness causes widespread structural and functional changes of the auditory system. In humans, the consequences of these changes are extensive and often include detriments to language acquisition and auditory perception. Fortunately, early intervention methods, such as cochlear implantation, can significantly mitigate inevitable auditory deficiencies. This review begins by briefly addressing early stages of brain development and associated anatomical discrepancies observed in congenitally deaf subjects. Considering the deleterious effects of congenital deafness, neuroplasticity, the ability of the brain to rewire itself, is of paramount importance in reversing the auditory impairments. Hence, its incorporation into the methods required for …