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Life Sciences Commons

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Journal

Biology

The Science Journal of the Lander College of Arts and Sciences

2009

Necrosis

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Bisphosphonates And Osteonecrosis Of The Jaw, Chaya Leah Katz Jan 2009

Bisphosphonates And Osteonecrosis Of The Jaw, Chaya Leah Katz

The Science Journal of the Lander College of Arts and Sciences

Bisphosphonate-related Osteonecrosis of the Jaw (BRONJ) is a condition which, according to the American Association of Oral and Maxillofacial Surgeons (AAOMS), adversely affects between .8-12percent of the population, a small yet significant amount of adults. Osteonecrosis of the Jaw (ONJ) is characterized by the death of bone and suffering patients present with either a non-healing extraction socket or an exposed jawbone. In general, afflicted patients have been treated with a class of drugs known as the Bisphosphonates (BP). Bisphosphonates were originally developed in order to treat and manage many metastatic diseases of the bone and stabilize bone loss caused by …