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Articles 1 - 10 of 10
Full-Text Articles in Life Sciences
Sound And The Moving Image:Critical Characteristics For Spectator Response, Kara Rader, Rafeeq I. Roberts, Matt Egizii, Jeffery Allen
Sound And The Moving Image:Critical Characteristics For Spectator Response, Kara Rader, Rafeeq I. Roberts, Matt Egizii, Jeffery Allen
Undergraduate Research Posters 2013
The prevailing wisdom in the film and video production industries is that audio information outweighs visual information when it comes to spectator responses, but there are few empirical studies to support this claim. In previous research, four critical characteristics of sound have been identified: (1) Music, (2) visual/sound contradictions (defined as sound that is inconsistent with audience expectations based on visual information), (3) multi-channel sound, and (4) sound quality. Building on our previous research into music and film, we have found that many researchers have looked into the question of how music affects emotions (Eschrich et al., 2008; Have, 2008; …
Role Of Programmed Proteolysis During Meiosis, Vincent Matthews, G. Valentin Borner Ph.D.
Role Of Programmed Proteolysis During Meiosis, Vincent Matthews, G. Valentin Borner Ph.D.
Undergraduate Research Posters 2013
Meiosis is the process which forms gametes and spores for reproduction in eukaryotic cells. During the pachytene phase of meiosis I, a protein structure, called the Synaptonemal Complex (SC), forms between homologous chromosomes and creates a scaffold for genetic recombination. In yeast, the Zip1 protein is a major structural component of the SC. At restrictive temperature for meiosis, ZIP1 is required for completion of meiotic divisions. At permissive temperature ZIP1 is required for proper chromosome segregation. We observed that chemical inhibition of the proteasome, with MG132, results in arrest at prophase of meiosis I. Based on these results, we questioned …
Exploring New Chemotherapeutic Strategies Against Brain Cancer, Seol Kim, Anthony J. Berdis
Exploring New Chemotherapeutic Strategies Against Brain Cancer, Seol Kim, Anthony J. Berdis
Undergraduate Research Posters 2013
Approximately 4,000 children in the United States are diagnosed each year with a brain tumor. Brain cancers are the deadliest of all pediatric cancers as they have survival rates of less than 20%. Typical treatments include surgery and radiation therapy. However, chemotherapy is the primary therapeutic option for children, especially against aggressive brain tumors. An important chemotherapeutic agent is temozolomide, an alkylating agent that causes cell death by damaging DNA. In this project, we tested the ability of non-natural nucleosides developed in our lab in order to increase the ability of temozolomide to kill brain cancer cells. Our results show …
A Quantitative Evaluation Of Growth In Leptodea Fragilis Before And After The Arrival Of Zebra Mussels In Lake Erie, Elizabeth Barkett, Robert A. Krebs, Matthew T. Begley
A Quantitative Evaluation Of Growth In Leptodea Fragilis Before And After The Arrival Of Zebra Mussels In Lake Erie, Elizabeth Barkett, Robert A. Krebs, Matthew T. Begley
Undergraduate Research Posters 2013
The arrival of zebra mussels in the Great Lakes in the 1980’s marked several environmental changes, most notably in freshwater mussels in the Unionidae. There are no studies of population demographics of native Great Lake species before this period of time. In this study, several recent shell collections of Leptodea fragilis, a fast-growing freshwater mussel, were made on various beaches along Lake Erie. To compare the effects of the zebra mussels on L. fragilis, we compared growth rates, determined from size and estimated age of shells, to additional collections of L. fragilis from 1941 to 1967available at the Cleveland Museum …
Functional Morphology Of Rat Hands And Feet: Correlation With The Ability To Grip Tree Branches During Locomotion, Jessica E. Fonce, Andrew R. Lammers
Functional Morphology Of Rat Hands And Feet: Correlation With The Ability To Grip Tree Branches During Locomotion, Jessica E. Fonce, Andrew R. Lammers
Undergraduate Research Posters 2013
Anatomy and function are usually closely related. Since locomotion on tree branches is common among mammals, we expect to find that the anatomy of the hands and feet is well-suited toward gripping narrow, cylindrical, branch-like substrates. We hypothesize that the ability of rats to grip arboreal supports relies on musculature responsible for adducting the first digit (thumb and big toe) and opposing medial-most and lateral-most digits. We dissected the hands and feet of four rat cadavers. There is a substantial muscle that may be responsible for the flexion/adduction of the thumb in the hands. We also found lumbricals, and dorsal …
Adaptation Of Scenedesmus Dimorphus To Brackish Water, Dustin Bowden, Joanne M. Belovich
Adaptation Of Scenedesmus Dimorphus To Brackish Water, Dustin Bowden, Joanne M. Belovich
Undergraduate Research Posters 2013
Microalgae is a promising biofuel feedstock for replacement of conventional transportation fuels. Microalgae does not require arable land for cultivation, and the biofuel production rate per acre of land is an order of magnitude greater than that needed for crop-based production methods. Though microalgae to biofuel processes are attractive, none have proven commercially successful due to the high costs of algae dewatering. Moreover, the scarcity of fresh water in many parts of the world prevents development of this process because of competition with drinking water supplies. Our lab has developed an efficient dewatering method using an inclined gravity settler. It …
Combining Orthogonal Trna/Synthatase Pair And Amber Codon Suppression To Genetically Encode Oxidative Damage In High Density Lipoproteins, Jaclyn Alatrash, Nicholas Gilliam, Alisha House, Valentin Gogonea
Combining Orthogonal Trna/Synthatase Pair And Amber Codon Suppression To Genetically Encode Oxidative Damage In High Density Lipoproteins, Jaclyn Alatrash, Nicholas Gilliam, Alisha House, Valentin Gogonea
Undergraduate Research Posters 2013
Apolipoprotein A-I (apoA-I) is the main protein constituent of high density lipoprotein (HDL - the “good cholesterol”). Oxidatively damaged apoA-I has been isolated from circulating plasma and atherosclerosis plaque with the amino acid residue tryptophan 72 (W72) of apoA-I identified as a primary oxidation site. ApoA-I designed to include specific oxidized amino acids can be used to further investigate the role of site-specific oxidative damage in atherosclerosis. Genetic encoding of oxidized amino acids through orthogonal tRNA/aminoacyl-tRNA synthetase (aaRS) pairs offers a reliable method for producing site-specific oxidized proteins. Our project involves the generation of Saccharomyces tryptophan-RS mutants for recognition of …
Climate Change From Oxygen Isotopic Variation Of Pore Water From Sediments In Punderson Lake, Northeast Ohio, Rachel Daley, Fasong Yuan
Climate Change From Oxygen Isotopic Variation Of Pore Water From Sediments In Punderson Lake, Northeast Ohio, Rachel Daley, Fasong Yuan
Undergraduate Research Posters 2013
The environment in Ohio has changed over time. The hydroclimate, which is the climate of the water, shows changes from the Industrial Revolution to the present. Evidence for these changes can be found in levels of δ18O and δ2H isotopes in the layers of sediment and water in the lakes of Northeast Ohio. Mass spectrometry can be used to test the levels of δ18O and δ2H isotopes from pore water samples within sediment cores. In this study, surface soil and water samples were collected from cores in Punderson Lake at Punderson State Park in Newbury, Ohio. Pore water was extracted …
Comparison Of Arsenic Uptake And Oxidative Stress By Christmas Fern And Spider Brake Fern, Paul Lkanich, Pratheek Koneru, Robert Wei
Comparison Of Arsenic Uptake And Oxidative Stress By Christmas Fern And Spider Brake Fern, Paul Lkanich, Pratheek Koneru, Robert Wei
Undergraduate Research Posters 2013
Plants are widely considered the most cost effective and environmentally friendly way to clean soils and waters contaminated with toxic metals, e.g. arsenic and mercury. We have focused our research on the uptake of arsenic and its biochemical effect on two species of fern, Spider brake fern and Christmas fern. Spider brake fern is known to be capable of accumulating significant amounts of arsenic. We wish to determine whether the levels of arsenic uptake in Christmas fern are comparable to Spider Brake fern (>1g kg-1 plant biomass) when both are grown under the same conditions. Another aim of the …
Function Of A Novel Checkpoint Protein In The Germ Line, Steven Drellishak, Marina Bykova, G. Valentin Börner
Function Of A Novel Checkpoint Protein In The Germ Line, Steven Drellishak, Marina Bykova, G. Valentin Börner
Undergraduate Research Posters 2013
Successful reproduction of Saccharomyces cerevisiae relies on the organism’s ability to complete the meiotic cell cycle and produce viable gametes. Zip1 is a protein that constitutes the central component of a protein structure that connects homologous chromosomes known as the synaptonemal complex. Zip1 is important for progression through the meiotic cell cycle. The C terminus of the coiled-coil Zip 1 protein is responsible for localization to the axes of the chromosomes. An internal deletion near the C terminus of Zip1, called zip1-c1, yields a stronger meiotic arrest than a mutation where Zip1 is completely deleted. The more efficient meiotic progression …