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Full-Text Articles in Life Sciences
Effect Of Basal Diet And Black Raspberry Supplementation On Gene Biomarkers Of "Leaky Gut" In Mouse Model Of Colitis-Associated Colorectal Cancer, Eliza Stewart
Fall Student Research Symposium 2021
Colorectal cancer is currently the third leading cause of cancer death in the world. The risk of developing colorectal cancer increases significantly in individuals who suffer from colitis, which is inflammation of the colon lining, seen in Irritable Bowel Disease. The term “leaky gut” is often used to describe increased intestinal permeability and is closely related to colitis. Leaky gut is associated with dysbiosis of the gut microbiota, which can occur through diet. This dysbiosis leads to pro-longed inflammation and affects genes that encode for proteins involved in the tight junctions between cells. Compromised intestinal integrity allows for translocation of …
Prebiotics, Probiotics, And Bacterial Infections, Christina C. Tam, Kirkwood M. Land, Luisa W. Cheng
Prebiotics, Probiotics, And Bacterial Infections, Christina C. Tam, Kirkwood M. Land, Luisa W. Cheng
College of the Pacific Faculty Books and Book Chapters
Bacterial pathogens have developed exquisite virulence mechanisms to survive in the host cells. These virulence mechanisms help them bind and internalize into host cells, replicate, and evade the host immune response. The mammalian host itself has developed its own repertoire of weapons to prevent this from happening. One important component of host response in preventing infections in the gut lumen is the diverse commensal microbiota present. Dysbiosis of the gut microbiota has been implicated in the development of many gastrointestinal diseases. A potential therapeutic pathway to solve these diseases would be by providing probiotics and/or prebiotics to help stimulate growth …