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Full-Text Articles in Life Sciences
In Vitro Gastrointestinal Digestion Model To Monitor The Antioxidant Properties And Bioaccessbility Of Phenolic Extracts From Elderberry (Sambucus Nigra L.), Ninghui Zhou
Wayne State University Theses
This study performed an in vitro gastrointestinal digestion model to monitor the antioxidant properties of phenolic extracts derived from the elderberry (Sambucus nigra L.). The stability and antioxidant qualities of phenolic compounds from elderberry were assessed by an in vitro gastrointestinal digestion model involving pepsin digestion (to simulate gastric digestion) and pancreatin digestion (to simulate small i22ntestine conditions). Digested and undigested elderberry were subject to antioxidant assays including total phenolic content (TPC) assay, DPPH radical scavenging assay, and oxygen radical absorbance capacity (ORAC) assay. Our result showed that digestion process significantly reduced DPPH radical scavenging activity but had no significant …
Comparitive Study On Antioxidant Properties Of Dendrobium Officinale (Tiepishihu), Wenjun Zhu
Comparitive Study On Antioxidant Properties Of Dendrobium Officinale (Tiepishihu), Wenjun Zhu
Wayne State University Theses
For ages, Chinese herbs, such as Dendrobium Officinale (DO), have been used in Asian regions for treating various illnesses due to the high medicinal value. In this study, the DO plant Acetone and Ethanolic extracts possibly containing antioxidants were tested using different methodologies for comparison and determination of specific antioxidant capacity. The total phenolic content assay expressed as Gallic Acid Equivalent showed 9.43±;0.23 mg GAE /g of extract. Further analysis using DPPH· assay indicated that antioxidants presented in the sample were able to significantly scavenge 37% and 44% radicals at the concentrations of 25mg/ml and 50mg/mL respectively, after a period …
Selenium Supplementation Increases Antioxidant Response In Vitro, Yasmin Fakhereddin
Selenium Supplementation Increases Antioxidant Response In Vitro, Yasmin Fakhereddin
Wayne State University Theses
Reactive oxygen species and free radicals are associated with the negative effects of aging. Enzymatic and non-enzymatic mechanisms can defend cell structures from free radical damage. Selenium is an essential trace element necessary for cellular functions in the human body. A positive correlation between low serum selenium levels with the morbidity and mortality of a range of cancers has been illustrated in numerous studies. Glutathione Peroxidase catalyzes a reaction in which H2O2 oxidizes the reduced form of GSH and forms H2O. NADPH further reduces GSSG, the oxidized structure of glutathione, in a reaction catalyzed by glutathione reductase. Tissue culture was …