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Turkish Journal of Veterinary & Animal Sciences

Antimicrobial peptide

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Effect Of Astragalus And Astragalus Polysaccharide On Antimicrobial Peptides Pr-39 And Protegrin-1 Gene Expression In Pigs, Youjin Tu, Yizhen Wang, Chunlan Xu, Guojia Yao, Tizhong Shan Jan 2006

Effect Of Astragalus And Astragalus Polysaccharide On Antimicrobial Peptides Pr-39 And Protegrin-1 Gene Expression In Pigs, Youjin Tu, Yizhen Wang, Chunlan Xu, Guojia Yao, Tizhong Shan

Turkish Journal of Veterinary & Animal Sciences

This experiment was conducted to study the effects of micron Astragalus, 80 mesh Astragalus and Astragalus polysaccharide (APS) on antimicrobial peptides PR-39 and protegrin-1 gene expression in pigs using semi-quantitative RT-PCR analysis. One hundred twenty 60-day-old Duroc x Landrace x Yorkshire piglets (21.88 ± 1.26 kg of average initial body weight) were randomly allotted to 4 treatments. Each treatment had 3 replicates (i.e. pens) with 10 pigs per pen. The basal diets were supplemented with 0, 5 g kg^{-1} APS, 5 g kg^{-1} 80 mesh Astragalus, and 5 g kg^{-1} micron Astragalus, respectively, and the feeding experiment lasted 30 days. …