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Design And In Vitro, In Vivo Evaluation Of Antioxidant Bioadhesive Gelsfor Burn Treatment, Göksel Gökçe, Si̇nem Yaprak Karavana, Hüsnü Alper Bağriyanik, Çeti̇n Pekçeti̇n, Evren Alğin Yapar, Gülşen Aybar Tural, Evren Homan Gökçe
Design And In Vitro, In Vivo Evaluation Of Antioxidant Bioadhesive Gelsfor Burn Treatment, Göksel Gökçe, Si̇nem Yaprak Karavana, Hüsnü Alper Bağriyanik, Çeti̇n Pekçeti̇n, Evren Alğin Yapar, Gülşen Aybar Tural, Evren Homan Gökçe
Turkish Journal of Biology
Burn wounds are frequently encountered health problems, which need a new treatment approach especially in terms of good patient compliance. Availability of use of antioxidant agents and bio-adhesive gels in tissue healing can be an alternative as a new approach for wound healing. Antioxidant taurine containing bio-adhesive gels were prepared by using carbopol (CP) 940 and 934. Rheological and texture analyses were carried out on bio-adhesive gels for in vitro characterization. Wound model on Wistar rats was used to evaluate the in vivo evaluation of gels. Rheological and texture analyses showed that a carbopol bioadhesive gel has acceptable topically use …