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Turkish Journal of Biology

Algae

Publication Year

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Brown Alga Sargassum Muticum Inhibits Proinflammatory Cytokines, Inos, And Cox-2 Expression In Macrophage Raw 264.7 Cells, Weon-Jong Yoon, Wook Jae Lee, Nam Ho Lee, Chang-Gu Hyun Jan 2010

Brown Alga Sargassum Muticum Inhibits Proinflammatory Cytokines, Inos, And Cox-2 Expression In Macrophage Raw 264.7 Cells, Weon-Jong Yoon, Wook Jae Lee, Nam Ho Lee, Chang-Gu Hyun

Turkish Journal of Biology

The present study was designed to elucidate the pharmacological and biological effects of Sargassum muticum extracts on the production of inflammatory mediators in macrophages. S. muticum was extracted with 80% EtOH. The extract was then successively partitioned with n-hexane, CH_2Cl_2, EtOAc, BuOH, and water. The results indicate that the CH_2Cl_2 fraction of S. muticum extract was an effective inhibitor of LPS-induced NO and PGE_2 production in RAW 264.7 cells. These inhibitory effects of the CH2Cl2 fraction of S. muticum included dose-dependent decreases in the expression of iNOS and COX-2 proteins and iNOS and COX-2 mRNA. To test the inhibitory effects …


Epipelic And Epilithic Algae Of The Yedigöller Lakes (Erzurum-Turkey), Bülent Şahi̇n Jan 2002

Epipelic And Epilithic Algae Of The Yedigöller Lakes (Erzurum-Turkey), Bülent Şahi̇n

Turkish Journal of Biology

The epipelic and epilithic algae of the Yedigöller Lakes were studied qualitatively between June and September 2001. As a result 90 taxa (43 belonging to Bacillariophyta, 33 to Chlorophyta, 11 to Cyanophyta and three to Euglenophyta) were determined. Based on the algal community composition, the Yedigöller Lakes can be characterized as oligotrophic.