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Blood, Serum Glucose And Renal Parameters In Lead-Loaded Albino Rats And Treatment With Some Chelating Agents And Natural Oils, Abd El Rahiem A. Ashour, Maged M. Yassin, Nahed M. Abu Aasi, Rokaya M. Ali
Blood, Serum Glucose And Renal Parameters In Lead-Loaded Albino Rats And Treatment With Some Chelating Agents And Natural Oils, Abd El Rahiem A. Ashour, Maged M. Yassin, Nahed M. Abu Aasi, Rokaya M. Ali
Turkish Journal of Biology
This study investigated lead impact on blood, serum glucose and kidney function and the efficacy of treatment with chelating agents meso-2,3-dimercaptosuccinic acid (DMSA), calcium disodium ethylenediaminetetraacetic acid (CaNa_2-EDTA) and natural olive and garlic oils to reduce lead toxicity in albino rats. Oral administration of 1000 or 2000 ppm lead acetate significantly decreased red blood cell count, hemoglobin level and hematocrit value at 20, 40 and 60 days compared with control groups (rats administered deionized water and 1000 or 2000 ppm sodium acetate). Serum glucose was also decreased significantly with both doses of lead acetate administration. In contrast, serum urea, uric …