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Full-Text Articles in Life Sciences
Comparative Cytotoxicity Of An Fda-Approved Cancer Drug To Extracts Of Atriplex Confertifolia On Human Breast And Cervical Cancer Cells, Christopher James Capua
Comparative Cytotoxicity Of An Fda-Approved Cancer Drug To Extracts Of Atriplex Confertifolia On Human Breast And Cervical Cancer Cells, Christopher James Capua
Theses and Dissertations
The severity and number of people affected by cancer is a worldwide problem with millions of people affected annually. The search for treatment and cures of cancer continues to be a global effort. As part of this global effort, many natural products have been tested against cancer cell lines, most from plants located in tropical regions. However, this study reports that extracts of Atriplex confertifolia, a native North American plant, has significant bioactivity against human breast cancer cell lines MCF-7, 435, and 231, and HeLa cells (cervical cancer cells). The bioactivity of A. confertifolia extracts of these cells lines was …
Role Of Vegf-C In Proliferation And Migration In A Cancer Model, Emily Marie Benke
Role Of Vegf-C In Proliferation And Migration In A Cancer Model, Emily Marie Benke
Theses and Dissertations
Head and neck cancer ranks high among the most common cancers world wide. In addition, there is a high recurrence rate, as well as a high prevalence of loco-regional tumor spread. Among many factors contributing to metastasis is vascular endothelial cell growth factor C. VEGF-C is primarily an inducer of new lymph vessel formation, typically during embryogenesis; however, some advanced cancers show a significant increase in VEGF-C expression, suggesting a role in metastasis. In the current study, the effects of VEGF-C expression were tested in HN12 cells, which are highly metastatic and known to express high levels of the chemokine …