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Articles 1 - 30 of 82
Full-Text Articles in Life Sciences
Ecology, Phylogenetics, And Conservation Of Draba Asterophora Complex: A Rare, Alpine, Endemic From Lake Tahoe, Usa, Emily Ruth Smith Putnam
Ecology, Phylogenetics, And Conservation Of Draba Asterophora Complex: A Rare, Alpine, Endemic From Lake Tahoe, Usa, Emily Ruth Smith Putnam
Theses and Dissertations
Rare, alpine, endemic species are particularly at risk for extinction. Alpine environments are especially vulnerable to climate change and human impacts, such as ski resort development and snowmaking. Draba asterophora Payson is a rare, alpine species that occurs only in three disjunct mountain-top regions surrounding Lake Tahoe. It is currently threatened by human impacts, such as ski resorts, as well as indirect influences of climate change and therefore in need of better understanding for conservation purposes. Draba asterophora may be able to serve as a case study for other similarly vulnerable, rare, alpine, endemic species with conservation needs. We utilized …
Post-Fire Interactions Between Soil Water Repellency, Islands Of Fertility, And Bromus Tectorum Invasibility, Kaitlynn Jane Fernelius
Post-Fire Interactions Between Soil Water Repellency, Islands Of Fertility, And Bromus Tectorum Invasibility, Kaitlynn Jane Fernelius
Theses and Dissertations
An intrinsic link exists between soil moisture and soil nitrogen. Factors that increase or decrease soil moisture can have a profound effect on soil nitrogen cycling, which may have later repercussions in the plant community. Post-fire soil water repellency is one factor that can limit soil moisture acquisition and may indirectly affect nitrogen cycling and weed invasion in woody islands of fertility. Plots centered on burned Juniperus osteosperma trees were either left untreated or treated with a surfactant to ameliorate water repellency. Two years later, soils were excavated from the untreated and treated field plots. In the greenhouse, half of …
Certain Agave Species Exhibit The Capability To Be Moderately Productive Under Conditions Of High Salt And Drought Stress, Steven J. Bergsten
Certain Agave Species Exhibit The Capability To Be Moderately Productive Under Conditions Of High Salt And Drought Stress, Steven J. Bergsten
Theses and Dissertations
Water availability and arable lands are increasingly limiting resources in many parts of the U.S., particularly in semi-arid and arid regions. As a means of addressing food and fuel demands associated with burgeoning population growth, highly productive and water-use efficient crops need to be identified. One potential crop, Agave, merits consideration and evaluation due to its putative capability to provide sustenance and energy despite growing in water-limited regions and on marginal soils. However, little is known regarding the productivity these succulent plants will have under growing conditions of the Southwest, where high concentrated saline soils are abundant, and water is …
Identification Of The Binding Partners For Hspb2 And Cryab Reveals Myofibril And Mitochondrial Protein Interactions And Non-Redundant Roles For Small Heat Shock Proteins, Kelsey Murphey Langston
Identification Of The Binding Partners For Hspb2 And Cryab Reveals Myofibril And Mitochondrial Protein Interactions And Non-Redundant Roles For Small Heat Shock Proteins, Kelsey Murphey Langston
Theses and Dissertations
Small Heat Shock Proteins (sHSP) are molecular chaperones that play protective roles in cell survival and have been shown to possess chaperone activity. As such, mutations in this family of proteins result in a wide variety of diseases from cancers to cardiomyopathies. The sHSPs Beta-2 (HspB2) and alpha-beta crystalline (CryAB) are two of the ten human sHSPs and are both expressed in cardiac and skeletal muscle cells. A heart that cannot properly recover or defend against stressors such as extreme heat or cold, oxidative/reductive stress, and heavy metal-induced stress will constantly struggle to maintain efficient function. Accordingly, CryAB is required …
Synthesis, Characterization, And Application Of High Surface Area, Mesoporous, Stabilized Anatase Tio2 Catalyst Supports, Rebecca Elizabeth Olsen
Synthesis, Characterization, And Application Of High Surface Area, Mesoporous, Stabilized Anatase Tio2 Catalyst Supports, Rebecca Elizabeth Olsen
Theses and Dissertations
Nanomaterials have attracted substantial attention in the area of catalysis due to the unique properties they exhibit such as high surface areas, intricate pore networks and unique morphologies. TiO2 has attracted attention as a catalyst since the discovery of its high photocatalytic activity by Fuishima and Honda in 1972. Given its high thermal stability, low cost, low environmental impact, and versatility, TiO2 is a widely used commercial catalyst and catalyst support. TiO2 is used in many applications such as photocatalysis is also an excellent support material for noble metals in a number of oxidative synthesis and pollution-control reactions. Though TiO2 …
Nonlinear Spectroscopic Investigation Of Adsorption To C-18 Model Stationary Phase, Anthony D. Peterson
Nonlinear Spectroscopic Investigation Of Adsorption To C-18 Model Stationary Phase, Anthony D. Peterson
Theses and Dissertations
Reversed-phase liquid chromatography (RPLC) is a commonly used separation technique in chemistry. Nevertheless, the mechanistic interactions at the molecular level among the eluent, analyte, and the stationary phase are not fully understood. Because of this limited understanding, optimization of the separation must be done experimentally. Learning more about molecular interactions should aid in improving separations. We are currently using second-harmonic generation (SHG) spectroscopy to investigate how analytes adsorb to the surface. SHG is a spectroscopic technique that produces signal only at places of non-isotropic symmetry; this typically occurs at surfaces. SHG can be used to produce surface isotherms of test …
Understory Vegetation Response To Mechanical Mastication Of Piñon And Juniper Woodlands, Jordan Ann Bybee
Understory Vegetation Response To Mechanical Mastication Of Piñon And Juniper Woodlands, Jordan Ann Bybee
Theses and Dissertations
Piñon and juniper encroachment and infilling can alter ecosystem processes and decrease resilience and resistance in sagebrush grasslands. Land managers employ a variety of techniques to eliminate these trees and mitigate their negative effects. Mechanical mastication or shredding is an increasingly popular method of removing these trees in Utah. It is a versatile treatment that can reduce canopy fuels, increase infiltration, and reduced sediment loss. We compared vegetation cover for annual and perennial vegetation functional groups on shredded and adjacent unshredded areas across a range of sites. Our approach was to categorize sites by ecological site type (encroachment or tree) …
The Acute Effects Of Whole-Body Vibration Training On Passive And Dynamic Flexibility In Gymnasts, Caisa Nicole Brooks
The Acute Effects Of Whole-Body Vibration Training On Passive And Dynamic Flexibility In Gymnasts, Caisa Nicole Brooks
Theses and Dissertations
Gymnasts must attain extreme ranges of flexibility to execute performance requirements, thus effective stretching proves vital to advancement in the sport. This study examined the acute effects of whole-body vibration (WBV) on passive and dynamic flexibility in young, female gymnasts. Participants (n = 27, Junior Olympic levels 5-10) served as their own control. Measurements of passive and dynamic flexibility were obtained using the TOPS forward split testing method to examine passive flexibility and dynamic flexibility was measured via split jumps that were analyzed with video and Dartfish software. According to randomized order, all participants completed a stretching protocol either with …
Pharmacokinetics Of Dexamethasone Delivered Via Iontophoresis, Justin Holbrook Rigby
Pharmacokinetics Of Dexamethasone Delivered Via Iontophoresis, Justin Holbrook Rigby
Theses and Dissertations
Study Design: Controlled laboratory study. Objectives: To determine the time course of dexamethasone sodium phosphate (Dex-P) iontophoresis delivery to underlying tissues using microdialysis. Background: The efficacy of iontophoresis at delivering Dex-P through the skin is unknown in humans because of the lack of minimally invasive measurement techniques. Methods: Sixty-four healthy male participants (age = 24.4 ± 3.3 yrs, height = 71.8 ± 2.5 in, weight = 181.8 ± 26.1 lbs) were randomly assigned into one of six groups: 1) 1 mA current, 1 mm probes depth ; 2) 1 mA current, 4 mm probes depth; 3) 2 mA current, 1 …
Formation And Analysis Of Zinc Oxide Nanoparticles And Zinc Oxide Hexagonal Prisms And Optical Analysis Of Cadmium Selenide Nanoparticles, Jared M. Hancock
Formation And Analysis Of Zinc Oxide Nanoparticles And Zinc Oxide Hexagonal Prisms And Optical Analysis Of Cadmium Selenide Nanoparticles, Jared M. Hancock
Theses and Dissertations
In this dissertation, methods to synthesize ZnO are reported. First, zinc oxide nanoparticles were synthesized with small amounts of transition metal ions to create materials called dilute magnetic semiconductors (DMS). We employed a low temperature sol-gel method that produces ZnO nanoparticles of reproducible size and incorporates cobalt, nickel, and manganese ions into the nanoparticles. Conditions were controlled such that a range of amounts of Co, Ni, and Mn were incorporated. The incorporation was tracked by color changes in the white ZnO powder to blue for Co, green for Ni and yellow for Mn. XRD measurements showed the nanoparticles were on …
Investigation Into The Effects Of Pegylation On The Thermodynamic Stability Of The Ww Domain, Sam S. Matthews
Investigation Into The Effects Of Pegylation On The Thermodynamic Stability Of The Ww Domain, Sam S. Matthews
Theses and Dissertations
The covalent attachment of poly(ethylene glycol) (PEG) to a protein surface (known as PEGylation), has been demonstrated to increase the serum half-life of therapeutic proteins by reducing kidney clearance and immunogenicity and by protecting against proteolysis. Theses beneficial effects could be further enhanced if PEGylation consistently increased protein conformational stability (i.e. the difference in free energy between the folded and unfolded states). However, the effects of PEGylation on protein conformational stability are unpredictable; PEGylation has been reported to increase, decrease, or have no effect on the conformational stability of medicinal proteins.This thesis details the results of two studies aimed at …
Fgf4 Induced Wnt5a Gradient In The Limb Bud Mediates Mesenchymal Cell Directed Migration And Division, John C. Allen
Fgf4 Induced Wnt5a Gradient In The Limb Bud Mediates Mesenchymal Cell Directed Migration And Division, John C. Allen
Theses and Dissertations
The AER has a vital role in directing embryonic limb development. Several models have been developed that attempt to explain how the AER directs limb development, but none of them are fully supported by existing data. I provide evidence that FGFs secreted from the AER induce a gradient of Wnt5a. I also demonstrate that limb mesenchyme grows toward increasing concentrations of Wnt5a. We hypothesize that the changing shape of the AER is critical for patterning the limb along the proximal to distal axis. To better understand the pathway through which Wnt5a elicits its effects, we have performed various genetic studies. …
Ferritin-Based Photo-Oxidation Of Biomass For Nanoparticle Synthesis, Bioremediation, And Hydrogen Evolution, Oscar Petrucci
Ferritin-Based Photo-Oxidation Of Biomass For Nanoparticle Synthesis, Bioremediation, And Hydrogen Evolution, Oscar Petrucci
Theses and Dissertations
The cell is the basic unit of all living organisms. It is an amazing machine capable of self-replicating, growing, and synthesizing and shuttling thousands of compounds. To perform all of these activities the cell needs energy. The original source of energy for all living beings is the Sun. The energy of the sun is collected by the autotrophs (mostly plants) through photosynthesis and stored in the chemical bonds of carbohydrates and lipids through carboxylic acid intermediates; animals use these compounds to obtain the energy for their cells. Most of the energy extracted by the cell comes from the citric acid …
Population Genetic Structure Of Bromus Tectorum In The American Desert Southwest, Desiree Rochelle Eldon
Population Genetic Structure Of Bromus Tectorum In The American Desert Southwest, Desiree Rochelle Eldon
Theses and Dissertations
Following its introduction to North America in the late nineteenth century, Bromus tectorum L., an inbreeding invasive winter annual grass, has become dominant on millions of hectares of sagebrush steppe habitat throughout Intermountain Western North America. It appears that within the last 30-40 years, B. tectorum has expanded its range southward into the Mojave Desert and also into more climatically extreme salt desert environments. Previous research using microsatellite markers and experimental studies has suggested that lineages found in desert habitats are genetically distinct from those found in the sagebrush-steppe habitat and possess suites of traits that pre-adapt them to these …
Importance Of Placement Depth In Evaluating Soil Nitrogen, Phosphorus, And Sulfur Using Ion Exchange Resin Capsules In Semi-Arid, Low Fertility Soils, Rachel Lynn Buck
Importance Of Placement Depth In Evaluating Soil Nitrogen, Phosphorus, And Sulfur Using Ion Exchange Resin Capsules In Semi-Arid, Low Fertility Soils, Rachel Lynn Buck
Theses and Dissertations
Ion exchange resin capsules provide a possible alternative to conventional soil testing procedures. Previous studies with semi-arid, low fertility soils observed poor relationships with poorly mobile nutrients such as phosphorus (P). We propose that placement depth may improve those relationships. Our objective was to (1) determine if placement depth could improve resin capsule estimation of the bioavailability of nitrogen (N), P, and sulfur (S) and (2) to determine if resin capsules can effectively estimate S availability in semi-arid, low fertility soils. Field sites were established in Rush and Skull Valleys, Utah on loam and sandy loam soils, respectively. Fertilizer was …
Endocannabinoid-Dependent Long-Term Depression Of Ventral Tegmental Area Gaba Neurons, Jared Mark Weed
Endocannabinoid-Dependent Long-Term Depression Of Ventral Tegmental Area Gaba Neurons, Jared Mark Weed
Theses and Dissertations
GABA neurons in the ventral tegmental area of the midbrain are important components in the brain's reward circuit. Long term changes in this circuit occur through the process of synaptic plasticity. It has been shown that high frequency stimulation, as well as treatment with endocannabinoids, can cause GABA neurons in the ventral tegmental area to undergo long term depression, a form of synaptic plasticity that decreases excitability of cells. The present study elaborates on the mechanism whereby high frequency stimulation can result in long term depression of ventral tegmental area GABA neurons. Using the whole cell patch clamp technique in …
Obstacles And Solutions To Studying Functional Adhesives Using Vibrational Sum-Frequency Generation Spectroscopy, Angela Renee Andersen
Obstacles And Solutions To Studying Functional Adhesives Using Vibrational Sum-Frequency Generation Spectroscopy, Angela Renee Andersen
Theses and Dissertations
Important aspects of adhesion occur at interfaces, including structures that may be different from those in the bulk materials. However, probing the orientation of molecules in functional adhesives poses a significant challenge because adhesive molecules are always located at a buried interface. The limited penetration depth of surface-specific analysis prohibits the study of buried interfaces using those techniques. The large quantity of bulk molecules relative to the adhesive molecules interacting at the interface results in the bulk signal swamping out adhesive signal in bulk analysis techniques. An interface-specific technique is required to study functional adhesives. One such technique that has …
Involvement Of Ampk And Ap-1 Biochemical Pathways In Il-6 Regulation Of Steroidogenic Enzymes In The Adrenal Cortex, Matharage Shenali De Silva
Involvement Of Ampk And Ap-1 Biochemical Pathways In Il-6 Regulation Of Steroidogenic Enzymes In The Adrenal Cortex, Matharage Shenali De Silva
Theses and Dissertations
The adrenal cortex is a crucial endocrine gland in the mammalian stress response. In chronic inflammatory stress, cortisol is elevated whereas adrenal androgens are decreased. Furthermore, ACTH levels have poor correlation with the plasma cortisol in these conditions, thus suggesting that other factors are driving the stress response during chronic inflammatory stress. Interleukin-6 (IL-6), a cytokine which is released during chronic inflammatory stress, is assumed to be one such factor. Thus the biochemical pathways by which IL-6 increases cortisol release from the zona fasciculata (ZF), and decreases adrenal androgen release from the zona reticularis (ZR) were investigated. Since IL-6 activates …
The Effects Of Isolation On Endemic Cozumel Island Rodents: A Test Of The Island Rule, Brittany Marie Nuttall
The Effects Of Isolation On Endemic Cozumel Island Rodents: A Test Of The Island Rule, Brittany Marie Nuttall
Theses and Dissertations
Island isolation can cause changes in body size, cranial characteristics, and genetic variation in mammals. We use geometric morphometrics to test skull and mandible shape and size change across three species of endemic Cozumel Island rodents in order to test the “island rule” of larger size in isolated rodents. We also sequenced the D-Loop and cytochrome b region of the mitochondrial genome and tested for differences in genetic variation between island and mainland groups, as well as population structure and gene flow in order to assess the effect of island isolation on these three rodents. We found that the three …
Application Of Next-Generation Transcriptomic Tools For Non-Model Organisms: Gene Discovery And Marker Developmentwithin Plecoptera (Insecta), Nicholas Gregory Davis
Application Of Next-Generation Transcriptomic Tools For Non-Model Organisms: Gene Discovery And Marker Developmentwithin Plecoptera (Insecta), Nicholas Gregory Davis
Theses and Dissertations
Phylogenetic research on non-model organisms has been hindered by limited marker availability. Next generation sequencing techniques are eliminating that barrier. Using Illumina sequencing technology, Trinity assembly software, custom Perl reciprocal BLAST scripts, and Primer3 primer prediction software, we produced and analyzed 7 Plecopteran transcriptomes, representing 7 of the 16 total families, in an attempt to identify and develop conserved orthologous genetic markers. The transcriptomes were used to reconstruct a gene content phylogeny using a simple distance matrix generated from reciprocal blastn data. By producing and filtering a reciprocal blast network we identified and aligned over 450 putative orthologs. Out of …
Utah Red Raspberry Jam: The Effects Of Formulation, Heating, And Time On Color, Flavor, Texture, And Antioxidant Capacity, Jennifer Leigh Chase
Utah Red Raspberry Jam: The Effects Of Formulation, Heating, And Time On Color, Flavor, Texture, And Antioxidant Capacity, Jennifer Leigh Chase
Theses and Dissertations
The amount and type of antioxidants present in raspberries is dependent upon cultivar, ripeness, and growing conditions. Previous research on raspberry jam has reported some color, antioxidant, and flavor loss after processing and storage, though it is unknown to what extent similar changes will occur in raspberries grown in Utah. Sugar concentration and heating temperature as well as storage time were evaluated in an effort to maximize color retention, flavor, antioxidant content, shelf life, and consumer acceptance of Utah-grown raspberry jam. Four types of jams were processed in two batches each: low-sugar (40-42 Brix) and typical sugar (65-68 Brix) at …
Regulation Of The Myostatin Protein In Overload-Induced Hypertrophied Rat Skeletal Muscle, Paige Abriel Affleck
Regulation Of The Myostatin Protein In Overload-Induced Hypertrophied Rat Skeletal Muscle, Paige Abriel Affleck
Theses and Dissertations
Myostatin (GDF-8) is the chief chalone in skeletal muscle and negatively controls adult skeletal muscle growth. The role of myostatin during overload-induced hypertrophy of adult muscle is unclear. We tested the hypothesis that overloaded adult rodent skeletal muscle would result in reduced myostatin protein levels. Overload-induced hypertrophy was accomplished by unilateral tenotomy of the gastrocnemius tendon in male adult Sprague-Dawley rats followed by a two-week period of compensatory overload of the plantaris and soleus muscles. Western blot analysis was performed to evaluate changes in active, latent and precursor myostatin protein levels. Significant hypertrophy was noted in the plantaris (494 ± …
Seasonal Changes In Body Composition, Block Jump, Attack Jump And Lower Body Power Index In Male Collegiate Volleyball Players, Geoffrey W. Loomis
Seasonal Changes In Body Composition, Block Jump, Attack Jump And Lower Body Power Index In Male Collegiate Volleyball Players, Geoffrey W. Loomis
Theses and Dissertations
Jumping ability in volleyball players is crucial to a team's success. There are both muscular and neural components in jumping. Coaches often test jumping ability and body composition prior to the start of the competitive season, but many fail to monitor these important variables during the course of the season. Jumping ability can decrease over the course of the season as the focus moves from strength training in the weight room to skill development on the court. It is imperative that players maintain their jumping ability and body composition over the course of the season. Seasonal changes in elite-male volleyball …
Habitat Selection By Two K-Selected Species: An Application To Bison And Sage Grouse, Joshua Taft Kaze
Habitat Selection By Two K-Selected Species: An Application To Bison And Sage Grouse, Joshua Taft Kaze
Theses and Dissertations
Population growth for species with long lifespans and low reproductive rates (i.e., K-selected species) is influenced primarily by both survival of adult females and survival of young. Because survival of adults and young is influenced by habitat quality and resource availability, it is important for managers to understand factors that influence habitat selection during the period of reproduction. My thesis contains two chapters addressing this issue for K-selected species in Utah. Chapter one evaluates habitat selection of greater sage-grouse (Centrocercusurophasianus) on Diamond Mountain during the critical nesting and brood-rearing period. Chapter two address selection of birth sites by bison (Bison …
Exploring Post-Fire Recovery Of Biocrusts And Desert Ecosystem Services, Jason R. Bahr
Exploring Post-Fire Recovery Of Biocrusts And Desert Ecosystem Services, Jason R. Bahr
Theses and Dissertations
Biocrusts and the ecosystem services they provide are becoming more susceptible to fire as exotic annual grass invasions facilitate the spread of desert wildfires. Further, precipitation patterns across the western United States are predicted to change over the next century, and have the potential to dramatically influence fire regimes and the recovery of burned biocrusts. Despite these changes to desert fire and precipitation cycles, our understanding of post-fire biocrust recovery is limited, especially regarding the first two years after fire. To investigate biocrust recovery, we created burn manipulations (i.e., unburned and burned) and tracked crust form and function over two …
Reading And Listening To Music Increase Resting Energy Expenditure During Indirect Calorimetry In Healthy Adults , Blaire Snell
Reading And Listening To Music Increase Resting Energy Expenditure During Indirect Calorimetry In Healthy Adults , Blaire Snell
Theses and Dissertations
The Academy of Nutrition and Dietetics has developed an evidence analysis library (EAL) for Nutrition and Dietetics professionals. The EAL is updated by members through workgroups consisting of experts in their fields, most often in response to unanswered questions. One such question is: what kinds of activities can be done during the rest period of an indirect calorimetry test in a healthy population? The objective of our study was to determine if listening to self-selected relaxing music or reading on an electronic device or a magazine effects resting energy expenditure (REE) as measured by an indirect calorimetry test in a …
Habitat Selection And Nesting Ecology Of Snowy Plover In The Great Basin, Kristen Sue Ellis
Habitat Selection And Nesting Ecology Of Snowy Plover In The Great Basin, Kristen Sue Ellis
Theses and Dissertations
Snowy plovers (Charadrius nivosus) are small, ground-nesting shorebirds that are a species of conservation concern throughout North America. Despite increased efforts to understand factors contributing to the decline of snowy plover, little is known about habitat selection and breeding ecology of snowy plover for the large population found in the Great Basin. We tested hypotheses concerning the occupancy and nesting success of snowy plover. First, we identified factors influencing snowy plover nest survival at Great Salt Lake, Utah. We hypothesized that snowy plover would demonstrate differences in nest survival rates across years due to differences in habitat characteristics, predator abundance, …
The Association Between Dairy Consumption And Insulin Resistance, Andrea Rose Erickson
The Association Between Dairy Consumption And Insulin Resistance, Andrea Rose Erickson
Theses and Dissertations
Background: A cross-sectional design was employed to ascertain the relationship between dairy consumption and insulin resistance (IR) in 272 middle-aged, nondiabetic women. Methods: Participants kept a seven-day weighed food record to report their diets, including consumption of dairy foods. IR was assessed using the homeostatic model assessment (HOMA), using the following formula: fasting plasma insulin (µU/ml) x fasting plasma glucose (mg/dL)/405. The Bod Pod was used to examine body fat percentage, and accelerometry over a seven-day period was used to assess physical activity. HOMA values were log-transformed and regression analysis and the General Linear Model procedure were used to determine …
The Relationship Between Television Viewing Time And Cardiorespiratory Fitness In Adult Women, Peter Jacob Arens
The Relationship Between Television Viewing Time And Cardiorespiratory Fitness In Adult Women, Peter Jacob Arens
Theses and Dissertations
Purpose: The present investigation was conducted to assess the relationship between television viewing time and cardiorespiratory fitness. Design: Cross-sectional. Setting: Intermountain West. Participants: 302 middle-aged women. Method: TV viewing was assessed using a questionnaire. Cardiorespiratory fitness was measured using a maximal graded treadmill test. Physical activity (PA) was evaluated using Actigraph accelerometers worn over seven consecutive days, while body fat percentage (BF%) was measured using air displacement plethysmography (Bod Pod). Results: (Mean ± SD) age: 40.2 ± 3.0 years. VO2max of the frequent (≥ 3hrs/day) TV group (32.6 ± 6.4) was significantly lower than both the moderate (1-2 hrs/day) (36.2 …
A Quadruplex Real-Time Pcr Assay For The Rapid Detection And Differentiation Of The Burkholderia Pseudomallei Complex: B. Mallei, B. Pseudomallei, And B. Thailandensis, Chinn-Woan Lowe
Theses and Dissertations
Methods for the rapid detection and differentiation of the Burkholderia pseudomallei complex comprising B. pseudomallei, B. mallei, and B. thailandensis, have been the topic of recent research due to the high degree of phenotypic and genotypic similarities of these species. B. pseudomallei and B. mallei are the causative agents of melioidosis and glanders, respectively. B. pseudomallei and B. mallei are recognized by the CDC as tier 1 select agents. Although B. thailandensis is generally avirulent in mammals, this species displays very similar phenotypic characteristics to that of B. pseudomallei. Optimal identification of these species remains problematic, …