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Full-Text Articles in Life Sciences
Fruits Of Averrhoa Carambola Inn Protects Wistar Rats Against Indomethacin And Pylorus Ligation- Induced Ulcers, Nireeksha G. Kulal, C. S. Shastry, Sharad Chand, Sawan Mukund Ghetia
Fruits Of Averrhoa Carambola Inn Protects Wistar Rats Against Indomethacin And Pylorus Ligation- Induced Ulcers, Nireeksha G. Kulal, C. S. Shastry, Sharad Chand, Sawan Mukund Ghetia
The Thai Journal of Pharmaceutical Sciences
Background: Peptic ulcer disease is one among the major cause of hospitalization in the gastroenterology department. Objective: The study was conducted to evaluate the gastroprotective and anti-ulcerogenic activity of Averrhoa carambola L. aqueous extract and its ghritha formulation on rat models. Materials and Methods: The antiulcer activity of A. carambola L. fruit extract was assessed by inducing ulcer using indomethacin and using pylorus ligation-induced ulcer models. The drug activity was compared to standard drugs omeprazole 30 mg/kg and sucralfate at a dose of 100 mg/kg. The parameters such as gastric pH, gastric acid volume, total acidity, free acidity, and ulcer …
Preparation Of Fast Release Indomethacin Solid Dispersion By Spray- Drying Using Lactose As Water-Soluble Carrier(การเตรียมอินโดเมธาชินโซลิดดิสเพอร์ชันชนิดปลดปล..., Pienkit Dangprasirt, Vasinee Limwong
Preparation Of Fast Release Indomethacin Solid Dispersion By Spray- Drying Using Lactose As Water-Soluble Carrier(การเตรียมอินโดเมธาชินโซลิดดิสเพอร์ชันชนิดปลดปล..., Pienkit Dangprasirt, Vasinee Limwong
The Thai Journal of Pharmaceutical Sciences
Solid dispersions of a poorly water-soluble drug, indomethacin (ID), in a water-soluble carrier, lactose, were prepared by coprecipitation method using a spray dryer. Dissolution tests were performed on the prepared ID and 1-2 IDdactose solid dispersion ...
Formation And Drug Entrapment Of Microcapsules Prepared From Chitosan-Carboxymethylcellulose Complex Coacervation, Gampimol C. Ritthidej, Waree Tiyaboonchai
Formation And Drug Entrapment Of Microcapsules Prepared From Chitosan-Carboxymethylcellulose Complex Coacervation, Gampimol C. Ritthidej, Waree Tiyaboonchai
The Thai Journal of Pharmaceutical Sciences
The formability of microcapsules was investigated by spraying carboxymethylcellulose solution into chitosan solution. The effect of concentration and pH of chitosan solution, the concentration of carboxymethylcellulose solution and the processing tempera...
In Vitro Release Characteristics Of Indomethacin Chitosan Beads, Satit Puttipipatkhachom, Kanya Anantakul
In Vitro Release Characteristics Of Indomethacin Chitosan Beads, Satit Puttipipatkhachom, Kanya Anantakul
The Thai Journal of Pharmaceutical Sciences
Indomethacin chitosan beads were prepared by ionotropic gelation with multivalent tripolyphosphate (TPP) ions. Various process variables such as amount of drug loading, chitosan gel concentration, TPP concentration and gelation time were investigated for...