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Full-Text Articles in Life Sciences
Cost-Effectiveness Analysis Of Manidipine Versus Amlodipine As An Add-On To Renin-Angiotensin System Blockers In Hypertensive Patients With Diabetes Mellitus And Proteinuria, Kamolpat Chaiyakittisopon, Wiwat Thavornwattanayong, Jadesada Lertsirimunkong, Supitchaya Senbut
Cost-Effectiveness Analysis Of Manidipine Versus Amlodipine As An Add-On To Renin-Angiotensin System Blockers In Hypertensive Patients With Diabetes Mellitus And Proteinuria, Kamolpat Chaiyakittisopon, Wiwat Thavornwattanayong, Jadesada Lertsirimunkong, Supitchaya Senbut
The Thai Journal of Pharmaceutical Sciences
Objectives: Diabetes and hypertension are the most common causes of chronic kidney disease. Calcium channel blockers are beneficial in blood pressure reduction while also stall kidney degeneration. The aim of this study was to compare the cost-effectiveness of manidipine to amlodipine as an add-on to renin-angiotensin system blockers (RASBs) to slow down kidney degeneration in hypertensive patients with diabetes mellitus and proteinuria. Methods: A lifetime Markov decision model was used to evaluate total costs and quality-adjusted life-years (QALYs) from published data on clinical outcomes and Thai data on cost and humanistic outcomes. This study adopted a societal perspective. Results: The …
High Dietary Salt Intake Alleviates Fasting Blood Glucose In Streptozotocin-Induced Diabetic Male Wistar Rats, Jerome Ndudi Asiwe, Kenneth Kelechi Anachuna, Emuesiri Goodies Moke, Kamaldeen Olalekan Sanusi, David Ehikhuemen Okonofua, Oghenerukevwe Omeru, Adesoji Adedipe Fasanmade
High Dietary Salt Intake Alleviates Fasting Blood Glucose In Streptozotocin-Induced Diabetic Male Wistar Rats, Jerome Ndudi Asiwe, Kenneth Kelechi Anachuna, Emuesiri Goodies Moke, Kamaldeen Olalekan Sanusi, David Ehikhuemen Okonofua, Oghenerukevwe Omeru, Adesoji Adedipe Fasanmade
The Thai Journal of Pharmaceutical Sciences
Objectives: Hypertension and type 2 diabetes are common comorbidities. Studies have shown that hypertension is twofold as common in diabetic patients compared with non-diabetics. Excessive intake of dietary salt has reportedly caused increase in blood pressure. This study investigated the effects of high dietary salt intake on diabetic rats. Materials and Methods: Twenty-eight animals were randomly selected into four groups (n = 7). Group 1 (normal control), fed with standard rats’ feed; Group 2 (diabetic control), streptozotocin-induced diabetic rats fed with normal diet; Group 3 (salt control), fed with 8% salt (high salt) diet; Group 4 (test group), streptozotocin-induced diabetic …
Hypoglycemic Activity Of Tridaxprocumbens Linn, In Rats(ฤทธิ์ของตีนตุ๊กแก ( Tridax Procumbens Linn.) ในการลดระดับนํ้าตาลในเลือดของหนูขาว), Kalaya Anulukanapakom, Orasa Pancharoen, Uraiwan Permpipat
Hypoglycemic Activity Of Tridaxprocumbens Linn, In Rats(ฤทธิ์ของตีนตุ๊กแก ( Tridax Procumbens Linn.) ในการลดระดับนํ้าตาลในเลือดของหนูขาว), Kalaya Anulukanapakom, Orasa Pancharoen, Uraiwan Permpipat
The Thai Journal of Pharmaceutical Sciences
In the Northeastern Thailand, an aqueous extract of a mixture of Tridax procumbens Linn. and Euphorbia hirta Linn, is taken orally to treat diabetes mellitus. In the present study, 95% ethanolic extract of T. procumbens (TP-1) was tested for hypoglycemic...