Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 4 of 4
Full-Text Articles in Life Sciences
Increased Contagious Itch In Children With Autism Spectrum Disorder (Asd), Molly Schineller
Increased Contagious Itch In Children With Autism Spectrum Disorder (Asd), Molly Schineller
Senior Theses and Projects
It has been previously demonstrated that contagion of yawning and laughter is significantly reduced in individuals with Autism Spectrum Disorder (ASD) in comparison to age-matched typically developing (TD) children, but contagion of itch has not been studied in this population. In this study, 55 children with ASD and 55 TD children, all aged 9-14, were exposed to video clips depicting actors yawning, laughing, and itching. In line with previous data, children with ASD demonstrated decreased contagious yawning and laughter in comparison to their TD peers. Surprisingly, they demonstrated increased contagious itch compared to their TD peers. However, susceptibility to contagion …
Does Gut Flora Change In A Mouse Model Of Autism Spectrum Disorders On A Ketogenic Diet?, Shelby A. Labe
Does Gut Flora Change In A Mouse Model Of Autism Spectrum Disorders On A Ketogenic Diet?, Shelby A. Labe
Senior Theses and Projects
The normal bacterial flora of an organism includes the non-disease causing bacteria that inhabit the human body under normal conditions. These bacteria are important for numerous reasons; for example, they excrete vitamins and prevent colonization by pathogens. Autism spectrum disorders (ASDs) are neurodevelopmental disorders that are characterized by social challenges, repetitive behaviors, and communication deficits. Comorbid conditions including gastrointestinal (GI) issues, depression, and anxiety are common. One popular way to attempt to alleviate the behavioral symptoms of ASDs is maintaining a ketogenic diet, which is seventy-five percent fat. Such a diet induces ketosis, a metabolic state when ketone bodies, not …
Effects Of Ketogenic Diets On Autistic Symptoms Of Female El Mice, Subrina N. Bisnauth
Effects Of Ketogenic Diets On Autistic Symptoms Of Female El Mice, Subrina N. Bisnauth
Senior Theses and Projects
The ketogenic diet (KD) is a restricted carbohydrate, high fat and sufficient protein metabolic therapy that elevates ketones as an alternative fuel source, and that reduces seizures in persons with epilepsy which is often comorbid with autism. Autism is characterized by communication deficits, decreased sociability and repetitive behaviours. A restrictive KD reverses symptoms in the BTBR mouse model of autism but its severity is a factor in its clinical applicability. In a study with the EL mouse model of epilepsy and autism, sex-dependent effects were found where only females displayed the behavioural effects of the KD. In the current study, …
The Effects Of Even- And Odd-Numbered Medium Chain Triglyceride Ketogenic Diets On Autistic Behaviors In A Mouse Model, Lisa Saa
Senior Theses and Projects
BACKGROUND: A ketogenic diet (KD), which has restricted carbohydrates, sufficient protein, and a very high fat content, causes the body to switch from a glucose-based metabolism to a ketone-based metabolism. The KD has been effective at reducing seizures in epileptic patients. Autism is comorbid with epilepsy and characterized by restricted and repetitive behaviors, low sociability, and deficits in communication. A strict version of the long-chain triglyceride (LCT) KD has been effective at reducing autistic symptoms in BTBR T+tf/J, an autistic model of mice. However, a more moderate and clinically relevant version of the LCT KD has been shown to be …