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Full-Text Articles in Life Sciences
Ultrastructure Of Dentin Matrix In Heritable Dentin Defects, J. Waltimo, H. Ranta, P. -L. Lukinmaa
Ultrastructure Of Dentin Matrix In Heritable Dentin Defects, J. Waltimo, H. Ranta, P. -L. Lukinmaa
Scanning Microscopy
Heritable dentin defects form a group of diseases which exclusively affect dentin among the various dental tissues. While one type is associated with the generalized connective tissue disorder, osteogenesis imperfecta, other types occur as single traits. The clinical manifestations of the dentin defects vary from insignificant to severe enough to cause aesthetical and functional failure of the teeth. Scanning and transmission electron microscopic studies, reviewed in this paper, have markedly clarified the ultrastructure of the aberrant dentin matrix. Both similar and different changes seem to occur in the various forms of heritable dentin defects. Abnormalities in the appearance and organization …
Scanning Electron Microscopic Study Of The Collagen Sheath Of The Human Thyroid Gland And Its Disorders, Masao Morita, Takuro Ogata, Keijiro Araki
Scanning Electron Microscopic Study Of The Collagen Sheath Of The Human Thyroid Gland And Its Disorders, Masao Morita, Takuro Ogata, Keijiro Araki
Scanning Microscopy
A cell-maceration/scanning electron microscope (SEM) method was employed to demonstrate the collagen sheath around follicles (perifollicular sheath) of the human thyroid gland and its disorders. In the normal thyroid gland, the follicles were surrounded by spherical collagen sheaths composed of a framework of thick collagen bands 1-5 μm in width and fine solitary collagen fibrils 50-70 nm in diameter. In benign thyroid diseases (Graves' disease, Hashimoto's thyroiditis and adenomatous goiter), the perifollicular sheaths differed in size and in shape according to the disease, but they were always composed of thick collagen bands and fine fibrils as in the normal thyroid. …
Scanning Electron Microscopic Study Of The Three-Dimensional Structure Of The Collagen Networks Of Gastric Cancer, Masuki Iyoki, Keijiro Araki, Takuro Ogata
Scanning Electron Microscopic Study Of The Three-Dimensional Structure Of The Collagen Networks Of Gastric Cancer, Masuki Iyoki, Keijiro Araki, Takuro Ogata
Scanning Microscopy
The three-dimensional structure of the collagen networks in human gastric carcinoma was examined by scanning electron microscopy (SEM) after treatment with the cell-maceration method using a low temperature NaOH solution. Based on stromal content, the poorly differentiated adenocarcinoma can be divided into the medullary carcinoma area and the scirrhous carcinoma area. In the medullary carcinoma, the collagen sheath around the small tumor cell acinus formed spherical chambers (20-30 μm in diameter) with fenestrations (about 5 μm in diameter) connecting the chambers. The collagen sheath was composed of fine collagen fibrils (about 50 nm in diameter). In the scirrhous area, there …
Radiation-Induced Fibrosis: The Structure/Function Relationship, J. C. Murray
Radiation-Induced Fibrosis: The Structure/Function Relationship, J. C. Murray
Scanning Microscopy
Fibrosis is a frequent complication of therapeutic radiation delivered to organ sites such as the thorax and pelvic region. We investigated the relationship between function, and biochemical and structural changes in the lung and colon of CBA mice irradiated with 240 kV X-rays. Progressive changes in lung function, as evidenced by increased breathing rates were observed out to 6 months post-irradiation. Biochemical studies demonstrated increased metabolism (synthesis and breakdown) of collagen around 6 months after irradiation, but provided no evidence of net collagen accumulation. Analysis of collagen isotypes revealed a slight increase in the ratio of types I and Ill. …