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Full-Text Articles in Life Sciences
Computational Labeling, Partitioning, And Balancing Of Molecular Networks, Biaobin Jiang
Computational Labeling, Partitioning, And Balancing Of Molecular Networks, Biaobin Jiang
Open Access Dissertations
Recent advances in high throughput techniques enable large-scale molecular quantification with high accuracy, including mRNAs, proteins and metabolites. Differential expression of these molecules in case and control samples provides a way to select phenotype-associated molecules with statistically significant changes. However, given the significance ranking list of molecular changes, how those molecules work together to drive phenotype formation is still unclear. In particular, the changes in molecular quantities are insufficient to interpret the changes in their functional behavior. My study is aimed at answering this question by integrating molecular network data to systematically model and estimate the changes of molecular functional …
Learning From Data: Plant Breeding Applications Of Machine Learning, Alencar Xavier
Learning From Data: Plant Breeding Applications Of Machine Learning, Alencar Xavier
Open Access Dissertations
Increasingly, new sources of data are being incorporated into plant breeding pipelines. Enormous amounts of data from field phenomics and genotyping technologies places data mining and analysis into a completely different level that is challenging from practical and theoretical standpoints. Intelligent decision-making relies on our capability of extracting from data useful information that may help us to achieve our goals more efficiently. Many plant breeders, agronomists and geneticists perform analyses without knowing relevant underlying assumptions, strengths or pitfalls of the employed methods. The study endeavors to assess statistical learning properties and plant breeding applications of supervised and unsupervised machine learning …