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Exploring The Glucocorticoid Actions Of 1Α-Hydroxycorticosterone (1Α-Oh-B) In The Elasmobranch Fishes, Faith Nichole Lambert
Exploring The Glucocorticoid Actions Of 1Α-Hydroxycorticosterone (1Α-Oh-B) In The Elasmobranch Fishes, Faith Nichole Lambert
Master's Theses
The corticosteroid 1α-hydroxycorticosterone (1α-OH-B) is unique to the elasmobranch fishes. It is thought that 1α-OH-B acts as both the primary glucocorticoid (GC) and mineralocorticoid (MC) in these fishes, a dual role analogous to that of cortisol in the teleost fishes. The MC characteristics of 1α-OH-B are well supported, but data supporting its GC functions are lacking. In this study, the putative GC actions of 1α-OH-B were examined. The first experiment characterized the physiological stress response of the Atlantic stingray (Dasyatis sabina) to air exposure, with particular regards to the roles of corticosteroids and metabolic fuels. Results demonstrate that …