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Full-Text Articles in Life Sciences

Unraveling The Functional Role Of The Orphan Solute Carrier, Slc22a24 In The Transport Of Steroid Conjugates Through Metabolomic And Genome-Wide Association Studies, Sook Wah Yee, Adrian Stecula, Huan-Chieh Chien, Ling Zou, Elena V Feofanova, Marjolein Van Borselen, Kit Wun Kathy Cheung, Noha A Yousri, Karsten Suhre, Jason M Kinchen, Eric Boerwinkle, Roshanak Irannejad, Bing Yu, Kathleen M Giacomini Sep 2019

Unraveling The Functional Role Of The Orphan Solute Carrier, Slc22a24 In The Transport Of Steroid Conjugates Through Metabolomic And Genome-Wide Association Studies, Sook Wah Yee, Adrian Stecula, Huan-Chieh Chien, Ling Zou, Elena V Feofanova, Marjolein Van Borselen, Kit Wun Kathy Cheung, Noha A Yousri, Karsten Suhre, Jason M Kinchen, Eric Boerwinkle, Roshanak Irannejad, Bing Yu, Kathleen M Giacomini

Journal Articles

Variation in steroid hormone levels has wide implications for health and disease. The genes encoding the proteins involved in steroid disposition represent key determinants of interindividual variation in steroid levels and ultimately, their effects. Beginning with metabolomic data from genome-wide association studies (GWAS), we observed that genetic variants in the orphan transporter, SLC22A24 were significantly associated with levels of androsterone glucuronide and etiocholanolone glucuronide (sentinel SNPs p-value


Saving Species, One Individual At A Time: Zoo Veterinarians Between Welfare And Conservation, Irus Braverman Apr 2018

Saving Species, One Individual At A Time: Zoo Veterinarians Between Welfare And Conservation, Irus Braverman

Journal Articles

The role of zoo veterinarians has changed significantly in the last several decades, reflecting and revealing broader transformations in zoo culture, especially among North American accredited zoos. This article draws on several interviews with prominent zoo vets, as well as on regulations that pertain to their work, to highlight their current position at the nexus of animal health and welfare, on the one hand, and of species conservation, on the other hand. The transformation of zoos into conservation institutions in particular has resulted in the vets’ novel focus on the sustainability of populations and their intensified involvement in in situ …


Global Patterns Of Freshwater Species Diversity, Threat And Cross-Taxon Congruence, Ben Collen Phd, Felix Whitton Phd, Ellie E. Dyer, Jonathan E.M. Baillie Phd, Neil Cumberlidge, William Darwall, Caroline Pollack, Nadia Richman Phd, Anne-Marie Soulsby, Monica Bohm Phd Jan 2014

Global Patterns Of Freshwater Species Diversity, Threat And Cross-Taxon Congruence, Ben Collen Phd, Felix Whitton Phd, Ellie E. Dyer, Jonathan E.M. Baillie Phd, Neil Cumberlidge, William Darwall, Caroline Pollack, Nadia Richman Phd, Anne-Marie Soulsby, Monica Bohm Phd

Journal Articles

Aim Global-scale studies are required to identify broad-scale patterns in the distributions of species, to evaluate the processes that determine diversity and to determine how similar or different these patterns and processes are among different groups of freshwater species. Broad-scale patterns of spatial variation in species distribution are central to many fundamental questions in macroecology and conservation biology. We aimed to evaluate how congruent three commonly used metrics of diversity were among taxa for six groups of freshwater species.

Location Global.

Methods We compiled geographical range data on 7083 freshwater species of mammals, amphibians, reptiles, fishes, crabs and crayfish to …


Looking At Zoos, Irus Braverman Oct 2011

Looking At Zoos, Irus Braverman

Journal Articles

Looking at zoos from the perspective of zoo personnel, this article explores the importance of vision in the zoo’s presentation of its animals as well as the major technologies that the zoo uses to intensify such animal visions. On the one end of the spectrum, zoogeography and immersion design are used at the zoo exhibit to enable zoogoers to see animals in their naturalistic settings. On the opposite end of the spectrum, animals are caged and cared for in the highly artificial settings of the zoo’s holding area, with little or no exposure to the public gaze. In between these …


"Insular Species Of Afrotropical Freshwater Crabs With Special Reference To Madagascar And The Seychelles" , Neil Cumberlidge Jan 2008

"Insular Species Of Afrotropical Freshwater Crabs With Special Reference To Madagascar And The Seychelles" , Neil Cumberlidge

Journal Articles

No abstract provided.