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Articles 1 - 3 of 3
Full-Text Articles in Life Sciences
Unravelling Organelle Genome Transcription Using Publicly Available Rna-Sequencing Data, Matheus Sanita Lima
Unravelling Organelle Genome Transcription Using Publicly Available Rna-Sequencing Data, Matheus Sanita Lima
Electronic Thesis and Dissertation Repository
The study of organelles helped forge theories of genome evolution because of their unconventional genomes and gene expression regimes. The organelle genomics field (~35 years old) has seen the development of next generation sequencing (NGS) techniques and the consequent skyrocketing of genomic and transcriptomic data. However, these data are being underused in the studies of organelle genome transcription. My thesis investigates how NGS has affected the field of organelle genomics at both the DNA and RNA levels. First, I demonstrate that although organelle genomes are being sequenced as never before, they are un-characterized as they are published mostly as “organelle …
Dynamic Functional Connectivity Reveals Temporal Differences In Wake And Stage-2 Sleep, Mazen El-Baba
Dynamic Functional Connectivity Reveals Temporal Differences In Wake And Stage-2 Sleep, Mazen El-Baba
Electronic Thesis and Dissertation Repository
The transition from wakefulness to sleep is marked by changes in neurophysiology, suggesting that changes in consciousness might be accompanied by changes in functional network organization. Brain activity of 21 healthy participants was measured via simultaneous EEG-fMRI as participants transitioned from wakefulness into sleep. All fMRI volumes were ICA-decomposed, yielding 42 neurophysiological sources. Independent component time courses were used to estimate mean functional connectivity (FC) and dynamic FC using a sliding window technique. Windowed matrices were submitted to k-means clustering (k = 7, L2-norm). Mean FC in Wake and Stage-2 Sleep (S2S) were similar. Dynamic analysis revealed differences in temporal …
Evolutionary Genetic Aspects Of Host Association In Generalist Ectoparasites, Benoit Talbot
Evolutionary Genetic Aspects Of Host Association In Generalist Ectoparasites, Benoit Talbot
Electronic Thesis and Dissertation Repository
Despite the use of the host for dispersal by most parasite species, the extremely loose relationship typical between highly mobile hosts and generalist ectoparasites may lead to very different gene flow patterns between the two, leading in turn to different spatial genetic structure, and potentially different demographic history. I examined how similar gene flow patterns are between Cimex adjunctus, a generalist ectoparasite of bats present throughout North America, and two of its key bat hosts. I first analyzed the continent-scale genetic structure and demographic history of C. adjunctus and compared it to that of two of its hosts, the …