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Full-Text Articles in Life Sciences
Local And Systemic Actions Of Gnrh Relating To Estradiol And Associated Reproductive Parameters In Beef Cattle, Jerica J.J. Rich
Local And Systemic Actions Of Gnrh Relating To Estradiol And Associated Reproductive Parameters In Beef Cattle, Jerica J.J. Rich
Electronic Theses and Dissertations
In cattle, estradiol is responsible for modulating many mechanisms involved in successful reproduction. Specifically estradiol is the primary signal for the initiation of standing estrus (Allrich, 1994), and cattle expressing estrus prior to fixed time AI (FTAI) have been reported to have increased preovulatory estradiol concentrations (Perry and Perry, 2008) and increased pregnancy success compared to animals that did not exhibit estrus (Richardson et al., 2016). Gonadotropin releasing hormone, classically, stimulates estradiol production via the two-cell two-gonadotropin hypothesis (Fortune and Quirk, 1988), and GnRH administered systemically in small doses (5 μg) has been reported to elicit an LH pulse similar …
Characterizing The Developmental And Reproductive Toxicities Of Cannabidiol And Δ9-Tetrahydrocannabinol, Dennis Ray Carty
Characterizing The Developmental And Reproductive Toxicities Of Cannabidiol And Δ9-Tetrahydrocannabinol, Dennis Ray Carty
Electronic Theses and Dissertations
Medical marijuana is legal in twenty-nine of the United States and an additional nineteen states have passed legislation for cannabidiol (CBD) treatment of drug-resistant epilepsy, such as Dravet Syndrome (DS) which is diagnosed in children as young as two months. While CBD has shown anecdotal and recently clinical trial efficacy in reducing seizure frequency in DS patients, little is known about the potential adverse side-effects on child physiology, brain development, adult disease, or subsequent generations. Moreover, CBD is rarely administered without including low concentrations of Δ9-tetrahydrocannabinol (THC). The goal of this project is to characterize the relative morphological, behavioral, reproductive, …