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Full-Text Articles in Life Sciences
Characterizing The Developmental And Reproductive Toxicities Of Cannabidiol And Δ9-Tetrahydrocannabinol, Dennis Ray Carty
Characterizing The Developmental And Reproductive Toxicities Of Cannabidiol And Δ9-Tetrahydrocannabinol, Dennis Ray Carty
Electronic Theses and Dissertations
Medical marijuana is legal in twenty-nine of the United States and an additional nineteen states have passed legislation for cannabidiol (CBD) treatment of drug-resistant epilepsy, such as Dravet Syndrome (DS) which is diagnosed in children as young as two months. While CBD has shown anecdotal and recently clinical trial efficacy in reducing seizure frequency in DS patients, little is known about the potential adverse side-effects on child physiology, brain development, adult disease, or subsequent generations. Moreover, CBD is rarely administered without including low concentrations of Δ9-tetrahydrocannabinol (THC). The goal of this project is to characterize the relative morphological, behavioral, reproductive, …
Macgillivray's Seaside Sparrow (Ammodramus Maritimus Macgillivraii) Breeding Biology & Population Density At Tom Yawkey Wildlife Center, Yianni P. Laskaris
Macgillivray's Seaside Sparrow (Ammodramus Maritimus Macgillivraii) Breeding Biology & Population Density At Tom Yawkey Wildlife Center, Yianni P. Laskaris
Electronic Theses and Dissertations
MacGillivray's Seaside Sparrow (Ammodramus maritimus macgillivraii) is a coastal marsh species sensitive to habitat alteration and threatened by coastal wetland loss. Data on seaside sparrow distribution, breeding success, and critical habitats are lacking in South Carolina. To better understand the demographics and incubation behavior of the species, I monitored breeding success, densities, song output, and presence of predators at three 7-hectare plots at the densest known population in the state. I also placed temperature data-loggers in a subset of nests to discern any links between incubation behavior and nest fate. Densities varied from a low of 5 birds/ha in a …
Benzo[A]Pyrene Effects On Fundulus Heteroclitus Reproductive Endpoints, Frank Booc
Benzo[A]Pyrene Effects On Fundulus Heteroclitus Reproductive Endpoints, Frank Booc
Electronic Theses and Dissertations
Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) that modulates aromatase enzyme function and, thus, potentially interrupts normal reproductive function. The aim of this study was to use a fish model, Fundulus heteroclitus, to assess whether BaP exposure adversely impacted reproduction. Adult fish were exposed to waterborne BaP concentrations of (0, 1 or 10 μg/L) for 28 days. Males and females were combined for the second half of the exposure (days 14-28) in order to quantitate egg production and fertilization success. Egg fertilization and subsequent hatching success of F1 embryos was significantly decreased by 10 μg/L BaP. In males, both …