Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 6 of 6

Full-Text Articles in Life Sciences

Metabolic Foundations Of Exercise-Induced Cardiac Growth., Kyle Fulghum Dec 2022

Metabolic Foundations Of Exercise-Induced Cardiac Growth., Kyle Fulghum

Electronic Theses and Dissertations

Regular aerobic exercise promotes physiological cardiac growth, which is an adaptive response thought to enable the heart to meet higher physical demands. Cardiac growth involves coordination of catabolic and anabolic activities to support ATP generation, macromolecule biosynthesis, and myocyte hypertrophy. Although previous studies suggest that exercise-induced reductions in cardiac glycolysis are critical for physiological myocyte hypertrophy, it remains unclear how exercise influences the many interlinked pathways of metabolism that support adaptive remodeling of the heart. In this thesis project, we tested the general hypothesis that aerobic exercise promotes physiological cardiac growth by coordinating myocardial metabolism to promote glucose-supported anabolic pathway …


Zebrafish As A Model To Understand The Impact Of Inactivity And Neuromuscular Electrical Stimulation On Duchenne Muscular Dystrophy, Elisabeth Kilroy Aug 2020

Zebrafish As A Model To Understand The Impact Of Inactivity And Neuromuscular Electrical Stimulation On Duchenne Muscular Dystrophy, Elisabeth Kilroy

Electronic Theses and Dissertations

Skeletal muscle plasticity is imperative for functional adaptation to changing demands in activity. Although a great deal is known about the structural and functional plasticity of healthy skeletal muscle, far less is known about plasticity in diseased muscle. Here, we combined the power of the zebrafish model with the adaptability of neuromuscular electrical stimulation (NMES) to study the basic mechanisms of plasticity in the zebrafish model of Duchenne Muscular Dystrophy (DMD). Four NMES paradigms, defined by their frequency, delay, and voltage, were designed to emulate the repetition and load schemes of human resistance training programs. Additionally, two inactivity paradigms were …


Comparison Of An Acute Bout Of Exercise To A Sugary Snack On Energy, Mood And Cognitive Performance, Erica Knowles May 2019

Comparison Of An Acute Bout Of Exercise To A Sugary Snack On Energy, Mood And Cognitive Performance, Erica Knowles

Electronic Theses and Dissertations

Low perceived energy and a decline in cognitive performance throughout the day are common issues, though exercise and food consumption are suggested to improve mood and cognition. The present study compares effects of acute exercise to consuming sugar on mood, energy, and cognitive performance. Subjects underwent blood glucose testing, completed an Abbreviated Profile of Mood States Questionnaire, and Automated Operation Span (OSPAN) and Digit Span tests to measure memory and attention. On two separate days subjects consumed candy or walked on a treadmill for 10 minutes, then measurements were repeated at 30-min, 60-min, and 120-min post. Two-way ANOVA over time …


The Effect Of Wild Blueberry Consumption On The Inflammatory Response, Oxidative Stress And Dna Damage Associated With Exercise, Taylor K. Bloedon Dec 2013

The Effect Of Wild Blueberry Consumption On The Inflammatory Response, Oxidative Stress And Dna Damage Associated With Exercise, Taylor K. Bloedon

Electronic Theses and Dissertations

At all levels of intensity and duration, exercise is known to cause an increase in the generation of reactive oxygen species (ROS). When derivatives of oxygen occur and exist independently with one or more unpaired electrons they are known as “free radicals” (Halliwell and Gutteridge 2007). Since atoms possess electrons that are usually associated in pairs, free radicals have the potential to act negatively in the body. Reactive oxygen species refer to oxygen-centered radicals as well as nonradical but reactive derivatives of oxygen (Halliwell and Gutteridge 2007). When ROS are created in excess, resulting in the disruption of the pro-oxidant/antioxidant …


Exercise Participation During Weight Loss On A High Protein – Low Carbohydrate Diet Plan In Females Aged 15-25 Years, Margaret Mobley-Meulman Aug 2013

Exercise Participation During Weight Loss On A High Protein – Low Carbohydrate Diet Plan In Females Aged 15-25 Years, Margaret Mobley-Meulman

Electronic Theses and Dissertations

Weight gain due to poor diet and lack of exercise is responsible for over 300,000 deaths each year (U.S. Department of Health and Human Services, 2010). Obese adults have an increased risk for serious health conditions including high blood pressure and cholesterol, type 2 diabetes, coronary heart disease, stroke, gallbladder disease, osteoarthritis, sleep apnea, respiratory problems, and certain cancers (National Cancer Institute, 2012). Participation in exercise can help control weight, strengthen muscles and bones, and reduce the incidence of cardiac events, stroke, hypertension, type 2 diabetes, colon and breast cancers, osteoporotic fractures, gallbladder disease, obesity, depression, anxiety, and delay mortality …


Effectiveness Of A Training Program Using An Alter-G Treadmill To Improve Physiological And Psychosocial Measures In Female Breast Cancer Survivors, Ciaran Fairman Jan 2013

Effectiveness Of A Training Program Using An Alter-G Treadmill To Improve Physiological And Psychosocial Measures In Female Breast Cancer Survivors, Ciaran Fairman

Electronic Theses and Dissertations

Breast survivors often experience lower bone mineral density following treatment, and may be at a higher risk for osteoporosis and consequent falls and injuries. This study aimed to build on previous research using lower impact exercise programs by using an anti-gravity (Alter-G®) treadmill to administer cardiovascular training. PURPOSE: The purpose of this study was to determine the effectiveness a physical activity program, including an anti-gravity (Alter-G) treadmill at improving physiological and psychosocial measures in female breast cancer survivors. METHODS: Five female breast cancer survivors were recruited to participate in the study. A 14-week intervention using an AB-AB study …