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Lysine Mediation Of Neuroendocrine Food Regulation In Guinea Fowl, Ashley C. Payne, Xiaofei Wang, Michael T. Ivy, A. Stewart, Kiimya Nelson, Carl E. Darris, Samuel N. Nahashon
Lysine Mediation Of Neuroendocrine Food Regulation In Guinea Fowl, Ashley C. Payne, Xiaofei Wang, Michael T. Ivy, A. Stewart, Kiimya Nelson, Carl E. Darris, Samuel N. Nahashon
Biology Faculty Research
In poultry, obesity is partly influenced by food intake, and is increasingly becoming a nationwide problem. Hypothalamic food intake mechanisms are involved metabolically and neurologically via two peptide hormones, leptin and ghrelin, and the amino acid glutamate, which is enzymatically derived from lysine metabolism. We hypothesize that lysine homeostasis mediates regulation of feed intake and performance characteristics via the brain–liver axis through glutamate sensing. The objective was to examine the effects of lysine homeostasis in avian food regulation and performance through neuroendocrine signaling. One-day-old male French Guinea fowl (GF) keets (n = 270) were weighed and randomly assigned to 5 …