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The Behavioral And Physiological Effects Of High-Fat Diet And Alcohol Consumption: Sex Differences In C57bl6/J Mice, Rachel R. Gelineau, Nicole L. Arruda, Jasmin A. Hicks, Isabella Monteiro De Pina, Aikaterini Hatzidis, Joseph A. Seggio
The Behavioral And Physiological Effects Of High-Fat Diet And Alcohol Consumption: Sex Differences In C57bl6/J Mice, Rachel R. Gelineau, Nicole L. Arruda, Jasmin A. Hicks, Isabella Monteiro De Pina, Aikaterini Hatzidis, Joseph A. Seggio
Biological Sciences Faculty Publications
Background and Objective: Animal studies can be a great tool to investigate sex differences in a variety of different ways, including behavioral and physiological responses to drug treatments and different “lifestyle variables” such as diets. Consumption of both high-fat diets and alcohol is known to affect anxiety behaviors and overall health. This project investigated how high-fat diet and alcohol access and its combination affected the behavior and physiology of male and female C57BL/6J mice.
Method: Mice were separated into three food groups: high-fat diet, 10% fat diet, and regular chow, and each group was paired with either water or 10% …