Life Sciences Commons^™

Impact Of Fish Oil On Intestinal Permeability, Inflammation, And Performance In Swine, Anthony Fernando Alberto

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Our research examined the effects of fish oil supplementation on intestinal permeability, systemic inflammation and performance in piglets. An lipopolysaccharide (LPS) challenge was done to stimulate the synthesis and release of the cytokines, in an effort to mimic the immune response that piglets would have when facing stress or pathogen challenge. Fish oil increased feed intake but did not affect growth when compared to control. Total fatty acid digestibility increased by 6% when fish oil was included in the diet. Also, we observed a 16% increase on 16-carbon fatty acids digestibility. Fish oil did not affect the plasma …

Effect Of Dietary Maillard Reaction Products On Insulin Sensitivity, Metabolic Inflammation And Intestinal Inflammation In Mice Fed The Total Western Diet, Siyu Xiao

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Maillard reaction products (MRPs) are generated when proteins or amino acids are heated with reducing sugars. In previous studies, baking whole diet pellets at a high temperature has been the most common way to promote MRP formation. However, baking diets also induces other chemical reactions besides MRP production, for example lipid oxidation. In this study, only casein and sugars were cooked to generate MRPs. Thus, a complementary experiment was conducted to determine how baking diet pellets affects lipid oxidation.

Previous rodent studies showed MRPs either induced weight gain and or impaired glucose tolerance. On the other hand, dietary MRPs were …